Activation of imidazoline I2B receptors by guanidine to increase glucose uptake in skeletal muscle of rats

Neuroscience Letters

Volumn 467, Issue 2, 2009, Pages 147-149

  Chang, Chin Hong ^a   Tsao, Chiung Wen ^b   Huang, Su Ying ^c   Cheng, Juei Tang ^a,c,d  

^a CHI MEI MEDICAL CENTER   (Taiwan)

^b CHUNG HWA UNIVERSITY OF MEDICAL TECHNOLOGY   (Taiwan)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^d CHANG JUNG CHRISTIAN UNIVERSITY   (Taiwan)

Author keywords

Amiloride; Diabetic rats; Glucose uptake; Guanidine; Imidazoline receptor; Plasma glucose

Indexed keywords

2 (2 IMIDAZOLIN 2 YL)QUINOLINE; AMILORIDE; GLUCOSE; GUANIDINE; IMIDAZOLINE I2B RECEPTOR; IMIDAZOLINE RECEPTOR; MU OPIATE RECEPTOR; NALOXONAZINE; NALOXONE; OPIATE; STREPTOZOCIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; DRUG RESPONSE; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; INSULIN DEPENDENT DIABETES MELLITUS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; SKELETAL MUSCLE; STREPTOZOCIN DIABETES; WISTAR RAT;

AMILORIDE; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; GLUCOSE; GUANIDINE; HYPOGLYCEMIC AGENTS; IMIDAZOLES; IMIDAZOLINE RECEPTORS; LIGANDS; MALE; MUSCLE, SKELETAL; RATS; RATS, WISTAR;

EID: 70350780057     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2009.10.026     Document Type: Article

References (18)

1. Cheng J.T., Liu I.M., Tzeng T.F., Tsai C.C., and Lai T.Y. Plasma glucose-lowering effect of beta-endorphin in streptozotocin-induced diabetic rats. Horm. Metab. Res. 34 (2002) 570-576
2. 2-imidazoline binding sites. Bioorg. Med. Chem. 14 (2006) 6570-6580
3. Dardonville C., and Rozas I. Imidazoline binding sites and their ligands: an overview of the different chemical structures. Med. Res. Rev. 24 (2004) 639-661
4. Diamant S., Eldar-Geva T., and Atlas D. Imidazoline binding sites in human placenta: evidence for heterogeneity and a search for physiological function. Br. J. Pharmacol. 106 (1992) 101-108
5. Hwang S.L., Liu I.M., Tzeng T.F., and Cheng J.T. Activation of imidazoline receptors in adrenal gland to lower plasma glucose in streptozotocin-induced diabetic rats. Diabetologia 48 (2005) 767-775
6. Jou S.B., Liu I.M., and Cheng J.T. Activation of imidazoline receptor by agmatine to lower plasma glucose in streptozotocin-induced diabetic rats. Neurosci. Lett. 358 (2004) 111-114
7. Ko W.C., Liu I.M., Chung H.H., and Cheng J.T. Activation of I(2)-imidazoline receptors may ameliorate insulin resistance in fructose-rich chow-fed rats. Neurosci. Lett. 448 (2008) 90-93
8. Liu I.M., Chi T.C., Chen Y.C., Lu F.H., and Cheng J.T. Activation of opioid mu-receptor by loperamide to lower plasma glucose in streptozotocin-induced diabetic rats. Neurosci. Lett. 265 (1999) 183-186
9. Molderings G.J., Likungu J., Jakschik J., and Gothert M. Presynaptic imidazoline receptors and non-adrenoceptor [3H]-idazoxan binding sites in human cardiovascular tissues. Br. J. Pharmacol. 122 (1997) 43-50
10. Oh S.J., Kim D.S., Head T.C., and Claussen G.C. Low-dose guanidine and pyridostigmine: relatively safe and effective long-term symptomatic therapy in Lambert-Eaton myasthenic syndrome. Muscle Nerve 20 (1997) 1146-1152
11. Raasch W., Schafer U., Chun J., and Dominiak P. Biological significance of agmatine, an endogenous ligand at imidazoline binding sites. Br. J. Pharmacol. 133 (2001) 755-780
12. Su C.F., Chang Y.Y., Pai H.H., Liu I.M., Lo C.Y., and Cheng J.T. Infusion of beta-endorphin improves insulin resistance in fructose-fed rats. Horm. Metab. Res. 36 (2004) 571-577
13. 2-imidazoline receptors by agmatine improved insulin sensitivity through two mechanisms in type-2 diabetic rats. Neurosci. Lett. 457 (2009) 125-128
14. Tzeng T.F., Lo C.Y., Cheng J.T., and Liu I.M. Activation of mu-opioid receptors improves insulin sensitivity in obese Zucker rats. Life Sci. 80 (2007) 1508-1516
15. 2-receptors. Ann. N. Y. Acad. Sci. 763 (1995) 43-56
16. Witters L.A. The blooming of the French lilac. J. Clin. Invest. 108 (2001) 1105-1107
17. Wu N., Su R.B., and Li J. Agmatine and imidazoline receptors: their role in opioid analgesia, tolerance and dependence. Cell Mol. Neurobiol. 28 (2008) 629-641
18. Yildiz G., Demiryurek A.T., Sahin-Erdemli I., and Kanzik I. Comparison of antioxidant activities of aminoguanidine, methylguanidine and guanidine by luminol-enhanced chemiluminescence. Br. J. Pharmacol. 124 (1998) 905-910