Protein kinase D1 mediates stimulation of DNA synthesis and proliferation in intestinal epithelial IEC-18 cells and in mouse intestinal crypts

Journal of Biological Chemistry

Volumn 286, Issue 1, 2011, Pages 511-520

  Sinnett Smith, James ^a   Rozengurt, Nora ^a   Kui, Robert ^a   Huang, Carlos ^a   Rozengurt, Enrique ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION LOOPS; ANGIOTENSIN II; AUTOPHOSPHORYLATION; CATALYTIC ACTIVITY; COUPLED RECEPTORS; CRYPT CELLS; DEOXYURIDINE; DNA SYNTHESISS; GENE SILENCING; IN-VITRO; IN-VIVO; INTESTINAL EPITHELIAL CELLS; INTESTINAL EPITHELIUM; MORPHOMETRIC ANALYSIS; PROTEIN KINASE; PROTEIN KINASE D1; SMALL INTERFERING RNA; TRANSGENIC MICE; TRANSGENICS;

BIOMATERIALS; CATALYST ACTIVITY; DNA; GENETIC ENGINEERING; PHOSPHORYLATION; PROTEINS;

CELL PROLIFERATION;

G PROTEIN COUPLED RECEPTOR; PROTEIN C FOS; PROTEIN KINASE C; PROTEIN KINASE D; PROTEIN KINASE D1; PROTEIN KINASE D2; SERINE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOPHOSPHORYLATION; CATALYSIS; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVATION; GENE SILENCING; INTESTINE CRYPT; INTESTINE EPITHELIUM CELL; INTESTINE MUCOSA; MORPHOMETRICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION;

ANIMALS; BIOCATALYSIS; CELL LINE; CELL PROLIFERATION; DNA; ENZYME ACTIVATION; GENE KNOCKDOWN TECHNIQUES; INTESTINAL MUCOSA; KINETICS; MICE; MICE, TRANSGENIC; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RECEPTORS, G-PROTEIN-COUPLED;

MUS; MUS MUSCULUS;

EID: 78650950730     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.167528     Document Type: Article

References (55)

1. van der Flier, L. G., and Clevers, H. (2009) Annu. Rev. Physiol. 71, 241-260
2. Rozengurt, E., and Sternini, C. (2007) Curr. Opin. Pharmacol. 7, 557-562
3. Podolsky, D. K. (1999) Am. J. Physiol. 277, G495-G499
4. Rozengurt, E., Rey, O., and Waldron, R. T. (2005) J. Biol. Chem. 280, 13205-13208
5. Iglesias, T., and Rozengurt, E. (1998) J. Biol. Chem. 273, 410-416
6. Iglesias, T., and Rozengurt, E. (1999) FEBS Lett. 454, 53-56
7. Waldron, R. T., and Rozengurt, E. (2003) J. Biol. Chem. 278, 154-163
8. Zugaza, J. L., Waldron, R. T., Sinnett-Smith, J., and Rozengurt, E. (1997) J. Biol. Chem. 272, 23952-23960
9. Zhukova, E., Sinnett-Smith, J., and Rozengurt, E. (2001) J. Biol. Chem. 276, 40298-40305
10. Zhukova, E., Sinnett-Smith, J., Wong, H., Chiu, T., and Rozengurt, E. (2001) J. Cell. Physiol. 189, 291-305
11. Chiu, T., and Rozengurt, E. (2001) FEBS Lett. 489, 101-106
12. Chiu, T., and Rozengurt, E. (2001) Am. J. Physiol. Cell Physiol. 280, C929-C942
13. Chiu, T., Wu, S. S., Santiskulvong, C., Tangkijvanich, P., Yee, H. F., Jr., and Rozengurt, E. (2002) Am. J. Physiol. Cell Physiol. 282, C434-C450
14. Guha, S., Rey, O., and Rozengurt, E. (2002) Cancer Res. 62, 1632-1640
15. Sinnett-Smith, J., Zhukova, E., Hsieh, N., Jiang, X., and Rozengurt, E. (2004) J. Biol. Chem. 279, 16883-16893
16. Waldron, R. T., Rey, O., Iglesias, T., Tugal, T., Cantrell, D., and Rozengurt, E. (2001) J. Biol. Chem. 276, 32606-32615
17. Yuan, J., Slice, L. W., and Rozengurt, E. (2001) J. Biol. Chem. 276, 38619-38627
18. Paolucci, L., Sinnett-Smith, J., and Rozengurt, E. (2000) Am. J. Physiol. Cell Physiol. 278, C33-C39
19. Yuan, J., Slice, L. W., Gu, J., and Rozengurt, E. (2003) J. Biol. Chem. 278, 4882-4891
20. Chiu, T. T., Leung, W. Y., Moyer, M. P., Strieter, R. M., and Rozengurt, E. (2007) Am. J. Physiol. Cell Physiol. 292, C767-C777
21. Yuan, J., Slice, L., Walsh, J. H., and Rozengurt, E. (2000) J. Biol. Chem. 275, 2157-2164
22. Yuan, J., Rey, O., and Rozengurt, E. (2006) Cell. Signal. 18, 1051-1062
23. Abedi, H., Rozengurt, E., and Zachary, I. (1998) FEBS Lett. 427, 209-212
24. Matthews, S. A., Iglesias, T., Rozengurt, E., and Cantrell, D. (2000) EMBO J. 19, 2935-2945
25. Matthews, S. A., Rozengurt, E., and Cantrell, D. (2000) J. Exp. Med. 191, 2075-2082
26. Matthews, S. A., Rozengurt, E., and Cantrell, D. (1999) J. Biol. Chem. 274, 26543-26549
27. Waldron, R. T., and Rozengurt, E. (2000) J. Biol. Chem. 275, 17114-17121
28. Waldron, R. T., Rey, O., Zhukova, E., and Rozengurt, E. (2004) J. Biol. Chem. 279, 27482-27493
29. Iglesias, T., Waldron, R. T., and Rozengurt, E. (1998) J. Biol. Chem. 273, 27662-27667
30. Jacamo, R., Sinnett-Smith, J., Rey, O., Waldron, R. T., and Rozengurt, E. (2008) J. Biol. Chem. 283, 12877-12887
31. Sinnett-Smith, J., Jacamo, R., Kui, R., Wang, Y. M., Young, S. H., Rey, O., Waldron, R. T., and Rozengurt, E. (2009) J. Biol. Chem. 284, 13434-13445
32. Brändlin, I., Hübner, S., Eiseler, T., Martinez-Moya, M., Horschinek, A., Hausser, A., Link, G., Rupp, S., Storz, P., Pfizenmaier, K., and Johannes, F. J. (2002) J. Biol. Chem. 277, 6490-6496
33. Sinnett-Smith, J., Zhukova, E., Rey, O., and Rozengurt, E. (2007) J. Cell. Physiol. 211, 781-790
34. Wang, Y., Waldron, R. T., Dhaka, A., Patel, A., Riley, M. M., Rozengurt, E., and Colicelli, J. (2002) Mol. Cell. Biol. 22, 916-926
35. Matthews, S. A., Liu, P., Spitaler, M., Olson, E. N., McKinsey, T. A., Cantrell, D. A., and Scharenberg, A. M. (2006) Mol. Cell. Biol. 26, 1569-1577
36. Storz, P., and Toker, A. (2003) EMBO J. 22, 109-120
37. Mihailovic, T., Marx, M., Auer, A., Van Lint, J., Schmid, M., Weber, C., and Seufferlein, T. (2004) Cancer Res. 64, 8939-8944
38. Quaroni, A., Wands, J., Trelstad, R. L., and Isselbacher, K. J. (1979) J. Cell Biol. 80, 248-265
39. Quaroni, A., and May, R. J. (1980) Methods Cell Biol. 21B, 403-427
40. Chiu, T., Santiskulvong, C., and Rozengurt, E. (2003) Am. J. Physiol. Gastrointest. Liver Physiol. 285, G1-G11
41. Chiu, T., Santiskulvong, C., and Rozengurt, E. (2005) Am. J. Physiol. Gastrointest. Liver Physiol. 288, G182-G194
42. Rey, O., Zhukova, E., Sinnett-Smith, J., and Rozengurt, E. (2003) J. Cell. Physiol. 196, 483-492
43. Santiskulvong, C., and Rozengurt, E. (2007) Cell. Signal. 19, 1348-1357
44. Jiang, X., Sinnett-Smith, J., and Rozengurt, E. (2007) Cell. Signal. 19, 1000-1010
45. Simon, T. C., Cho, A., Tso, P., and Gordon, J. I. (1997) J. Biol. Chem. 272, 10652-10663
46. Zugaza, J. L., Sinnett-Smith, J., Van Lint, J., and Rozengurt, E. (1996) EMBO J. 15, 6220-6230
47. Rozengurt, E., Rodriguez-Pena, M., and Smith, K. A. (1983) Proc. Natl. Acad. Sci. U.S.A. 80, 7244-7248
48. Brooks, S. F., Herget, T., Erusalimsky, J. D., and Rozengurt, E. (1991) EMBO J. 10, 2497-2505
49. Brooks, S. F., Herget, T., Broad, S., and Rozengurt, E. (1992) J. Biol. Chem. 267, 14212-14218
50. Erusalimsky, J. D., Brooks, S. F., Herget, T., Morris, C., and Rozengurt, E. (1991) J. Biol. Chem. 266, 7073-7080
51. Young, L. H., Balin, B. J., and Weis, M. T. (2005) Cardiovasc. Drug Rev. 23, 255-272
52. Van Lint, J. V., Sinnett-Smith, J., and Rozengurt, E. (1995) J. Biol. Chem. 270, 1455-1461
53. Valverde, A. M., Sinnett-Smith, J., Van Lint, J., and Rozengurt, E. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 8572-8576
54. Crosnier, C., Stamataki, D., and Lewis, J. (2006) Nat. Rev. Genet. 7, 349-359
55. Bostick, R. M., Fosdick, L., Grandits, G. A., Lillemoe, T. J., Wood, J. R., Grambsch, P., Louis, T. A., and Potter, J. D. (1997) Cancer Epidemiol. Biomarkers Prev. 6, 1011-1019