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Volumn 652, Issue 1-3, 2011, Pages 121-125

Protective effect of geranylgeranylacetone against loxoprofen sodium-induced small intestinal lesions in rats

Author keywords

Enterobacteria; Geranylgeranylacetone (GGA); NSAID; Sialomucin; Small intestine

Indexed keywords

LOXOPROFEN; MUCIN; SIALOMUCIN; TEPRENONE;

EID: 78650921172     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.11.020     Document Type: Article
Times cited : (15)

References (32)
  • 1
    • 0019846683 scopus 로고
    • Efficacy of anti-ulcer drugs on the recovery of gastric mucosal glycoproteins with aspirin-induced gastric damage in rat
    • Y. Azuumi, K. Ishihara, S. Ohara, H. Okabe, and K. Hotta Efficacy of anti-ulcer drugs on the recovery of gastric mucosal glycoproteins with aspirin-induced gastric damage in rat Gastroenterol. Jpn 16 1981 331 334
    • (1981) Gastroenterol. Jpn , vol.16 , pp. 331-334
    • Azuumi, Y.1    Ishihara, K.2    Ohara, S.3    Okabe, H.4    Hotta, K.5
  • 3
    • 0034899291 scopus 로고    scopus 로고
    • Geranylgeranylacetone promotes induction and secretion of thioredoxin in gastric mucosal cells and peripheral blood lymphocytes
    • H. Dekigai, H. Nakamura, J. Bai, M. Tanito, H. Masutani, K. Hirota, H. Matsui, M. Murakami, and J. Yodoi Geranylgeranylacetone promotes induction and secretion of thioredoxin in gastric mucosal cells and peripheral blood lymphocytes Free Radic. Res. 35 2001 23 30
    • (2001) Free Radic. Res. , vol.35 , pp. 23-30
    • Dekigai, H.1    Nakamura, H.2    Bai, J.3    Tanito, M.4    Masutani, H.5    Hirota, K.6    Matsui, H.7    Murakami, M.8    Yodoi, J.9
  • 4
    • 0020043538 scopus 로고
    • Effects of geranylgeranylacetone on gastrointestinal secretion in rats
    • M. Fujimoto, T. Yamanaka, M. Bessho, and T. Igarashi Effects of geranylgeranylacetone on gastrointestinal secretion in rats Eur. J. Pharmacol. 77 1982 113 118
    • (1982) Eur. J. Pharmacol. , vol.77 , pp. 113-118
    • Fujimoto, M.1    Yamanaka, T.2    Bessho, M.3    Igarashi, T.4
  • 5
    • 0030038266 scopus 로고    scopus 로고
    • Geranylgeranylacetone induces heat shock proteins in cultured guinea pig gastric mucosal cells and rat gastric mucosa
    • DOI 10.1053/gast.1996.v111.pm8690199
    • T. Hirakawa, K. Rokutan, T. Nikawa, and K. Kishi Geranylgeranylacetone induces heat shock proteins in cultured guinea pig gastric mucosal cells and rat gastric mucosa Gastroenterology 111 1996 345 357 (Pubitemid 26256722)
    • (1996) Gastroenterology , vol.111 , Issue.2 , pp. 345-357
    • Hirakawa, T.1    Rokutan, K.2    Nikawa, T.3    Kishi, K.4
  • 6
    • 0032492576 scopus 로고    scopus 로고
    • Lipopolysaccharide activates endothelial nitric oxide synthase through protein tyrosine kinase
    • K.T. Huang, L. Kuo, and J.C. Liao Lipopolysaccharide activates endothelial nitric oxide synthase through protein tyrosine kinase Biochem. Biophys. Res. Commun. 245 1998 33 37
    • (1998) Biochem. Biophys. Res. Commun. , vol.245 , pp. 33-37
    • Huang, K.T.1    Kuo, L.2    Liao, J.C.3
  • 7
    • 0028013354 scopus 로고
    • Effects of acid-inhibitory antiulcer drugs on mucin biosynthesis in the rat stomach
    • T. Ichikawa, K. Ishihara, K. Saigenji, and K. Hotta Effects of acid-inhibitory antiulcer drugs on mucin biosynthesis in the rat stomach Eur. J. Pharmacol. 251 1994 107 111
    • (1994) Eur. J. Pharmacol. , vol.251 , pp. 107-111
    • Ichikawa, T.1    Ishihara, K.2    Saigenji, K.3    Hotta, K.4
  • 8
    • 1542323256 scopus 로고    scopus 로고
    • Immunohistchemical localization in rat gastrointestinal tract of a sialomucin species recognized by HCM31, a new anti-mucin monoclonal antibody
    • T. Ikezawa, Y. Goso, T. Ichikawa, H. Hayashida, T. Nakamura, M. Kurihara, I. Okayasu, K. Saigenji, and K. Ishihara Immunohistchemical localization in rat gastrointestinal tract of a sialomucin species recognized by HCM31, a new anti-mucin monoclonal antibody Biomed. Res. 23 2002 63 68
    • (2002) Biomed. Res. , vol.23 , pp. 63-68
    • Ikezawa, T.1    Goso, Y.2    Ichikawa, T.3    Hayashida, H.4    Nakamura, T.5    Kurihara, M.6    Okayasu, I.7    Saigenji, K.8    Ishihara, K.9
  • 9
    • 0022621236 scopus 로고
    • Increasing action of teprenone, a new antiulcer agent, on high-molecular-weight glycoprotein in gastric mucus during the healing process of acetic acid-induced ulcer in rats
    • M. Ito, T. Tanaka, and Y. Suzuki Increasing action of teprenone, a new antiulcer agent, on high-molecular-weight glycoprotein in gastric mucus during the healing process of acetic acid-induced ulcer in rats Jpn J. Pharmacol. 41 1986 117 125
    • (1986) Jpn J. Pharmacol. , vol.41 , pp. 117-125
    • Ito, M.1    Tanaka, T.2    Suzuki, Y.3
  • 10
    • 84940363565 scopus 로고    scopus 로고
    • Effects of indomethacin on the rat small intestinal mucosa: Immunohistochemical and biochemical studies using anti-mucin monoclonal antibodies
    • T. Iwai, T. Ichikawa, Y. Goso, T. Ikezawa, Y. Saegusa, I. Okayasu, K. Saigenji, and K. Ishihara Effects of indomethacin on the rat small intestinal mucosa: immunohistochemical and biochemical studies using anti-mucin monoclonal antibodies J. Gastroenterol. 44 2009 277 284
    • (2009) J. Gastroenterol. , vol.44 , pp. 277-284
    • Iwai, T.1    Ichikawa, T.2    Goso, Y.3    Ikezawa, T.4    Saegusa, Y.5    Okayasu, I.6    Saigenji, K.7    Ishihara, K.8
  • 11
    • 0032962224 scopus 로고    scopus 로고
    • Nitric oxide, superoxide radicals and mast cells in pathogenesis of indomethacin-induced small intestinal lesions in rats
    • A. Konaka, M. Nishijima, A. Tanaka, T. Kunikata, S. Kato, and K. Takeuchi Nitric oxide, superoxide radicals and mast cells in pathogenesis of indomethacin-induced small intestinal lesions in rats J. Physiol. Pharmacol. 50 1999 25 38 (Pubitemid 29162052)
    • (1999) Journal of Physiology and Pharmacology , vol.50 , Issue.1 , pp. 25-38
    • Konaka, A.1    Nishijima, M.2    Tanaka, A.3    Kunikata, T.4    Kato, S.5    Takeuchi, K.6
  • 12
    • 35748970752 scopus 로고    scopus 로고
    • Long-term effects of nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 selective agents on the small bowel: A cross-sectional capsule enteroscopy study
    • L. Maiden, B. Thjodleifsson, A. Seigal, I.I. Bjarnason, D. Scott, S. Birgisson, and I. Bjarnason Long-term effects of nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 selective agents on the small bowel: a cross-sectional capsule enteroscopy study Clin. Gastroenterol. Hepatol. 5 2007 1040 1045
    • (2007) Clin. Gastroenterol. Hepatol. , vol.5 , pp. 1040-1045
    • Maiden, L.1    Thjodleifsson, B.2    Seigal, A.3    Bjarnason, I.I.4    Scott, D.5    Birgisson, S.6    Bjarnason, I.7
  • 15
    • 0033027343 scopus 로고    scopus 로고
    • Suppression of ethanol-induced apoptotic DNA fragmentation by geranylgeranylacetone in cultured guinea pig gastric mucosal cells
    • T. Mizushima, S. Tsutsumi, K. Rokutan, and T. Tsuchiya Suppression of ethanol-induced apoptotic DNA fragmentation by geranylgeranylacetone in cultured guinea pig gastric mucosal cells Dig. Dis. Sci. 44 1999 510 514 (Pubitemid 29137959)
    • (1999) Digestive Diseases and Sciences , vol.44 , Issue.3 , pp. 510-514
    • Mizushima, T.1    Tsutsumi, S.2    Rokutan, K.3    Tsuchiya, T.4
  • 16
    • 0019508881 scopus 로고
    • Antiulcer effect of geranylgeranylacetone, a new acyclic polyisoprenoid on experimentally induced gastric and duodenal ulcers in rats
    • M. Murakami, K. Oketani, H. Fujisaki, T. Wakabayashi, and T. Ohgo Antiulcer effect of geranylgeranylacetone, a new acyclic polyisoprenoid on experimentally induced gastric and duodenal ulcers in rats Arzneimittelforschung 31 1981 799 804
    • (1981) Arzneimittelforschung , vol.31 , pp. 799-804
    • Murakami, M.1    Oketani, K.2    Fujisaki, H.3    Wakabayashi, T.4    Ohgo, T.5
  • 17
    • 0020026655 scopus 로고
    • Effects of the antiulcer drug geranylgeranylacetone on aspirin-induced gastric ulcers in rats
    • M. Murakami, K. Oketani, H. Fujisaki, T. Wakabayashi, T. Ohgo, and S. Okabe Effects of the antiulcer drug geranylgeranylacetone on aspirin-induced gastric ulcers in rats Jpn J. Pharmacol. 32 1982 299 306
    • (1982) Jpn J. Pharmacol. , vol.32 , pp. 299-306
    • Murakami, M.1    Oketani, K.2    Fujisaki, H.3    Wakabayashi, T.4    Ohgo, T.5    Okabe, S.6
  • 21
    • 0026586024 scopus 로고
    • Alternating laminated array of two types of mucin in the human gastric surface mucous layer
    • H. Ota, and T. Katsuyama Alternating laminated array of two types of mucin in the human gastric surface mucous layer Histochem. J. 24 1992 86 92
    • (1992) Histochem. J. , vol.24 , pp. 86-92
    • Ota, H.1    Katsuyama, T.2
  • 22
    • 0031014088 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drug enteropathy in rats: Role of permeability, bacteria, and enterohepatic circulation
    • B.K. Reuter, N.M. Davies, and J.L. Wallace Nonsteroidal anti-inflammatory drug enteropathy in rats: role of permeability, bacteria, and enterohepatic circulation Gastroenterology 112 1997 109 117
    • (1997) Gastroenterology , vol.112 , pp. 109-117
    • Reuter, B.K.1    Davies, N.M.2    Wallace, J.L.3
  • 23
    • 0016774453 scopus 로고
    • An intestinal disease produced experimentally by a prostaglandin deficiency
    • A. Robert An intestinal disease produced experimentally by a prostaglandin deficiency Gastroenterology 69 1975 1045 1047
    • (1975) Gastroenterology , vol.69 , pp. 1045-1047
    • Robert, A.1
  • 24
    • 0033774810 scopus 로고    scopus 로고
    • Geranylgeranylacetone stimulates mucin synthesis in cultured guinea pig gastric pit cells by inducing a neuronal nitric oxide synthase
    • K. Rokutan, S. Teshima, T. Kawai, T. Kawahara, K. Kusumoro, T. Mizushima, and K. Kishi Geranylgeranylacetone stimulates mucin synthesis in cultured guinea pig gastric pit cells by inducing a neuronal nitric oxide synthase J. Gastroenterol. 35 2000 673 681
    • (2000) J. Gastroenterol. , vol.35 , pp. 673-681
    • Rokutan, K.1    Teshima, S.2    Kawai, T.3    Kawahara, T.4    Kusumoro, K.5    Mizushima, T.6    Kishi, K.7
  • 25
    • 11144267102 scopus 로고    scopus 로고
    • 2-Aminopurine inhibits lipopolysaccharide-induced nitric oxide production by preventing IFN-β production
    • T. Sugiyama, M. Fujita, N. Koide, I. Mori, T. Yoshida, H. Mori, and T. Yokochi 2-aminopurine inhibits lipopolysaccharide-induced nitric oxide production by preventing IFN-beta production Microbiol. Immunol. 48 2004 957 963 (Pubitemid 40040703)
    • (2004) Microbiology and Immunology , vol.48 , Issue.12 , pp. 957-963
    • Sugiyama, T.1    Fujita, M.2    Koide, N.3    Mori, I.4    Yoshida, T.5    Mori, H.6    Yokochi, T.7
  • 26
    • 0036970711 scopus 로고    scopus 로고
    • Pathogenic importance of intestinal hypermotility in NSAID-induced small intestinal damage in rats
    • K. Takeuchi, T. Miyazawa, A. Tanaka, S. Kato, and T. Kunikata Pathogenic importance of intestinal hypermotility in NSAID-induced small intestinal damage in rats Digestion 66 2002 30 41
    • (2002) Digestion , vol.66 , pp. 30-41
    • Takeuchi, K.1    Miyazawa, T.2    Tanaka, A.3    Kato, S.4    Kunikata, T.5
  • 27
    • 0022533634 scopus 로고
    • Protective action of tetraprenylacetone against ethanol-induced damage in rat gastric mucosa
    • A. Terano, J. Shiga, H. Hiraishi, S. Ota, and T. Sugimoto Protective action of tetraprenylacetone against ethanol-induced damage in rat gastric mucosa Digestion 35 1986 182 188
    • (1986) Digestion , vol.35 , pp. 182-188
    • Terano, A.1    Shiga, J.2    Hiraishi, H.3    Ota, S.4    Sugimoto, T.5
  • 28
    • 33947240786 scopus 로고    scopus 로고
    • A monoclonal antibody, PGM34, against 6-sulfated blood-group H type 2 antigen, on the carbohydrate moiety of mucin
    • D. Tsubokawa, Y. Goso, A. Sawaguchi, M. Kurihara, T. Ichikawa, N. Sato, T. Suganuma, K. Hotta, and K. Ishihara A monoclonal antibody, PGM34, against 6-sulfated blood-group H type 2 antigen, on the carbohydrate moiety of mucin FEBS J. 274 2007 1833 1848
    • (2007) FEBS J. , vol.274 , pp. 1833-1848
    • Tsubokawa, D.1    Goso, Y.2    Sawaguchi, A.3    Kurihara, M.4    Ichikawa, T.5    Sato, N.6    Suganuma, T.7    Hotta, K.8    Ishihara, K.9
  • 29
    • 70349968218 scopus 로고    scopus 로고
    • Nippostrongylus brasiliensis: Increase of sialomucins reacting with anti-mucin monoclonal antibody HCM31 in rat small intestinal mucosa with primary infection and reinfection
    • D. Tsubokawa, T. Nakamura, Y. Goso, Y. Takano, M. Kurihara, and K. Ishihara Nippostrongylus brasiliensis: increase of sialomucins reacting with anti-mucin monoclonal antibody HCM31 in rat small intestinal mucosa with primary infection and reinfection Exp. Parasitol. 123 2009 319 325
    • (2009) Exp. Parasitol. , vol.123 , pp. 319-325
    • Tsubokawa, D.1    Nakamura, T.2    Goso, Y.3    Takano, Y.4    Kurihara, M.5    Ishihara, K.6
  • 31
    • 0021967179 scopus 로고
    • Indometacin-induced gastrointestinal lesions in relation to tissue concentration, food intake and bacterial invasion in the rat
    • U. Weissenborn, S. Maedge, D. Buettner, and K.F. Sewing Indometacin-induced gastrointestinal lesions in relation to tissue concentration, food intake and bacterial invasion in the rat Pharmacology 30 1985 32 39
    • (1985) Pharmacology , vol.30 , pp. 32-39
    • Weissenborn, U.1    Maedge, S.2    Buettner, D.3    Sewing, K.F.4
  • 32
    • 24944433414 scopus 로고    scopus 로고
    • Correlation of gastric mucosal damage with sialic acid profile in rats: Effect of hydrochloric acid, pepsin and hypertonic saline
    • S. Yusuf, A.J. Nok, D.A. Ameh, A.B. Adelaiye, and E.O. Balogun Correlation of gastric mucosal damage with sialic acid profile in rats: effect of hydrochloric acid, pepsin and hypertonic saline Cell Biochem. Funct. 23 2005 339 345
    • (2005) Cell Biochem. Funct. , vol.23 , pp. 339-345
    • Yusuf, S.1    Nok, A.J.2    Ameh, D.A.3    Adelaiye, A.B.4    Balogun, E.O.5


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