메뉴 건너뛰기




Volumn 24, Issue 1, 2011, Pages 90-97

Stem cell markers (cytokeratin 15, cytokeratin 19 and p63) in in situ and invasive cutaneous epithelial lesions

Author keywords

actinic keratosis; bowenoid papulosis; CK15; CK19; p63; squamous cell carcinoma; squamous cell carcinoma in situ

Indexed keywords

BIOLOGICAL MARKER; CYTOKERATIN 15; CYTOKERATIN 19; PROTEIN P63;

EID: 78650920411     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2010.180     Document Type: Article
Times cited : (49)

References (40)
  • 1
    • 70849134501 scopus 로고    scopus 로고
    • Epidermal stem cells: Practical perspectives and potential uses
    • Abbas O, Mahalingam M. Epidermal stem cells: practical perspectives and potential uses. Br J Dermatol 2009;161:228-236.
    • (2009) Br J Dermatol , vol.161 , pp. 228-236
    • Abbas, O.1    Mahalingam, M.2
  • 2
    • 44949254968 scopus 로고    scopus 로고
    • Immuno-phenotyping of the human bulge region: The quest to define useful in situ markers for human epithelial hair follicle stem cells and their niche
    • Kloepper JE, Tiede S, Brinckmann J, et al. Immuno-phenotyping of the human bulge region: the quest to define useful in situ markers for human epithelial hair follicle stem cells and their niche. Exp Dermatol 2008;17:592-609.
    • (2008) Exp Dermatol , vol.17 , pp. 592-609
    • Kloepper, J.E.1    Tiede, S.2    Brinckmann, J.3
  • 3
    • 33947120191 scopus 로고    scopus 로고
    • Putative cancer stem cells in cutaneous malignancies
    • Kamstrup MR, Gniadecki R, Skovgaard GL. Putative cancer stem cells in cutaneous malignancies. Exp Dermatol 2007;16:297-301.
    • (2007) Exp Dermatol , vol.16 , pp. 297-301
    • Kamstrup, M.R.1    Gniadecki, R.2    Skovgaard, G.L.3
  • 4
    • 33845702260 scopus 로고    scopus 로고
    • Increased expression of stem cell markers in malignant melanoma
    • Klein WM, Wu BP, Zhao S, et al. Increased expression of stem cell markers in malignant melanoma. Mod Pathol 2007;20:102-107.
    • (2007) Mod Pathol , vol.20 , pp. 102-107
    • Klein, W.M.1    Wu, B.P.2    Zhao, S.3
  • 5
    • 52649180613 scopus 로고    scopus 로고
    • Expression of the hair stem cell-specific marker nestin in epidermal and follicular tumors
    • Kanoh M, Amoh Y, Sato Y, et al. Expression of the hair stem cell-specific marker nestin in epidermal and follicular tumors. Eur J Dermatol 2008;18:518-523.
    • (2008) Eur J Dermatol , vol.18 , pp. 518-523
    • Kanoh, M.1    Amoh, Y.2    Sato, Y.3
  • 6
    • 0242460440 scopus 로고    scopus 로고
    • Manipulation of stem cell proliferation and lineage commitment: Visualisation of label-retaining cells in whole mounts of mouse epidermis
    • Braun KM, Niemann C, Jensen UB, et al. Manipulation of stem cell proliferation and lineage commitment: visualisation of label-retaining cells in whole mounts of mouse epidermis. Development 2003;130: 5241-5255.
    • (2003) Development , vol.130 , pp. 5241-5255
    • Braun, K.M.1    Niemann, C.2    Jensen, U.B.3
  • 7
    • 0031721687 scopus 로고    scopus 로고
    • The C8 144B monoclonal antibody recognizes cytokeratin 15 and defines the location of human hair follicle stem cells
    • Lyle S, Christofidou-Solomidou M, Liu Y, et al. The C8 144B monoclonal antibody recognizes cytokeratin 15 and defines the location of human hair follicle stem cells. J Cell Sci 1998;111:3179-3188.
    • (1998) J Cell Sci , vol.111 , pp. 3179-3188
    • Lyle, S.1    Christofidou-Solomidou, M.2    Liu, Y.3
  • 8
    • 60449118357 scopus 로고    scopus 로고
    • Stem cell markers (cytokeratin 15, CD34 and nestin) in primary scarring and nonscarring alopecia
    • Hoang MP, Keady M, Mahalingam M. Stem cell markers (cytokeratin 15, CD34 and nestin) in primary scarring and nonscarring alopecia. Br J Dermatol 2009; 160:609-615.
    • (2009) Br J Dermatol , vol.160 , pp. 609-615
    • Hoang, M.P.1    Keady, M.2    Mahalingam, M.3
  • 9
    • 51649104164 scopus 로고    scopus 로고
    • Involvement of the bulge region in primary scarring alopecia
    • Pozdnyakova O, Mahalingam M. Involvement of the bulge region in primary scarring alopecia. J Cutan Pathol 2008;35:922-925.
    • (2008) J Cutan Pathol , vol.35 , pp. 922-925
    • Pozdnyakova, O.1    Mahalingam, M.2
  • 10
    • 0342517272 scopus 로고    scopus 로고
    • Human hair follicle bulge cells are biochemically distinct and possess an epithelial stem cell phenotype
    • Lyle S, Christofidou-Solomidou M, Liu Y, et al. Human hair follicle bulge cells are biochemically distinct and possess an epithelial stem cell phenotype. J Investig Dermatol Symp Proc 1999;4:296-301.
    • (1999) J Investig Dermatol Symp Proc , vol.4 , pp. 296-301
    • Lyle, S.1    Christofidou-Solomidou, M.2    Liu, Y.3
  • 11
    • 0029970965 scopus 로고    scopus 로고
    • Keratin 19 as a biochemical marker of skin stem cells in vivo and in vitro: Keratin 19 expressing cells are differentially localized in function of anatomic sites, and their number varies with donor age and culture stage
    • Michel M, Török N, Godbout MJ, et al. Keratin 19 as a biochemical marker of skin stem cells in vivo and in vitro: keratin 19 expressing cells are differentially localized in function of anatomic sites, and their number varies with donor age and culture stage. J Cell Sci 1996;109:1017-1028.
    • (1996) J Cell Sci , vol.109 , pp. 1017-1028
    • Michel, M.1    Török, N.2    Godbout, M.J.3
  • 12
    • 21644485644 scopus 로고    scopus 로고
    • A perspective on keratinocyte stem cells as targets for skin carcinogenesis
    • Morris RJ. A perspective on keratinocyte stem cells as targets for skin carcinogenesis. Differentiation 2004;72: 381-386.
    • (2004) Differentiation , vol.72 , pp. 381-386
    • Morris, R.J.1
  • 15
    • 33644686446 scopus 로고    scopus 로고
    • P63 deficiency: A failure of lineage commitment or stem cell maintenance?
    • Koster MI, Kim S, Roop DR. p63 deficiency: a failure of lineage commitment or stem cell maintenance? J Investig Dermatol Symp Proc 2005;10:118-123.
    • (2005) J Investig Dermatol Symp Proc , vol.10 , pp. 118-123
    • Koster, M.I.1    Kim, S.2    Roop, D.R.3
  • 16
    • 0032957338 scopus 로고    scopus 로고
    • Cytokeratin 15 expression in trichoepitheliomas and a subset of basal cell carcinomas suggests they originate from hair follicle stem cells
    • Jih DM, Lyle S, Elenitsas R, et al. Cytokeratin 15 expression in trichoepitheliomas and a subset of basal cell carcinomas suggests they originate from hair follicle stem cells. J Cutan Pathol 1999;26:113-118.
    • (1999) J Cutan Pathol , vol.26 , pp. 113-118
    • Jih, D.M.1    Lyle, S.2    Elenitsas, R.3
  • 17
    • 33846264532 scopus 로고    scopus 로고
    • Sebaceous tumours contain a subpopulation of cells expressing the keratin 15 stem cell marker
    • Bieniek R, Lazar AJ, Photopoulos C, et al. Sebaceous tumours contain a subpopulation of cells expressing the keratin 15 stem cell marker. Br J Dermatol 2007;156:378-380.
    • (2007) Br J Dermatol , vol.156 , pp. 378-380
    • Bieniek, R.1    Lazar, A.J.2    Photopoulos, C.3
  • 18
    • 38649096944 scopus 로고    scopus 로고
    • Microcystic adnexal carcinoma: An immunohistochemical reappraisal
    • Hoang MP, Dresser KA, Kapur P, et al. Microcystic adnexal carcinoma: an immunohistochemical reappraisal. Mod Pathol 2008;21:178-185.
    • (2008) Mod Pathol , vol.21 , pp. 178-185
    • Hoang, M.P.1    Dresser, K.A.2    Kapur, P.3
  • 19
    • 0029919109 scopus 로고    scopus 로고
    • Hereditary cancer: Two hits revisited
    • Knudson AG. Hereditary cancer: two hits revisited. J Cancer Res Clin Oncol 1996;122:135-140.
    • (1996) J Cancer Res Clin Oncol , vol.122 , pp. 135-140
    • Knudson, A.G.1
  • 20
    • 34250844983 scopus 로고    scopus 로고
    • Hair follicle stem cells: Walking the maze
    • Tiede S, Kloepper JE, Bodo E, et al. Hair follicle stem cells: walking the maze. Eur J Cell Biol 2007;86: 355-376.
    • (2007) Eur J Cell Biol , vol.86 , pp. 355-376
    • Tiede, S.1    Kloepper, J.E.2    Bodo, E.3
  • 21
    • 28444486367 scopus 로고    scopus 로고
    • Stem cell niche: Structure and function
    • Li L, Xie T. Stem cell niche: structure and function. Annu Rev Cell Dev Biol 2005;21:605-631.
    • (2005) Annu Rev Cell Dev Biol , vol.21 , pp. 605-631
    • Li, L.1    Xie, T.2
  • 22
    • 24644494270 scopus 로고    scopus 로고
    • Asymmetric cell divisions promote stratification and differentiation of mammalian skin
    • Lechler T, Fuchs E. Asymmetric cell divisions promote stratification and differentiation of mammalian skin. Nature 2005;437:275-280.
    • (2005) Nature , vol.437 , pp. 275-280
    • Lechler, T.1    Fuchs, E.2
  • 23
    • 13344262695 scopus 로고    scopus 로고
    • Normal and leukemic SCID-repopulating cells (SRC) coexist in the bone marrow and peripheral blood from CML patients in chronic phase, whereas leukemic SRC are detected in blast crisis
    • Sirard C, Lapidot T, Vormoor J, et al. Normal and leukemic SCID-repopulating cells (SRC) coexist in the bone marrow and peripheral blood from CML patients in chronic phase, whereas leukemic SRC are detected in blast crisis. Blood 1996;87:1539-1548.
    • (1996) Blood , vol.87 , pp. 1539-1548
    • Sirard, C.1    Lapidot, T.2    Vormoor, J.3
  • 24
    • 0034141934 scopus 로고    scopus 로고
    • A primitive hematopoietic cell is the target for the leukemic transformation in human philadelphia-positive acute lymphoblastic leukemia
    • Cobaleda C, Gutiérrez-Cianca N, Pérez-Losada J, et al. A primitive hematopoietic cell is the target for the leukemic transformation in human philadelphia-positive acute lymphoblastic leukemia. Blood 2000;95: 1007-1013.
    • (2000) Blood , vol.95 , pp. 1007-1013
    • Cobaleda, C.1    Gutiérrez-Cianca, N.2    Pérez-Losada, J.3
  • 25
    • 0141842674 scopus 로고    scopus 로고
    • Identification of a cancer stem cell in human brain tumors
    • Singh SK, Clarke ID, Terasaki M, et al. Identification of a cancer stem cell in human brain tumors. Cancer Res 2003;63:5821-5828.
    • (2003) Cancer Res , vol.63 , pp. 5821-5828
    • Singh, S.K.1    Clarke, I.D.2    Terasaki, M.3
  • 26
    • 0028534860 scopus 로고
    • The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype
    • Morrison SJ, Weissman IL. The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype. Immunity 1994;1: 661-673.
    • (1994) Immunity , vol.1 , pp. 661-673
    • Morrison, S.J.1    Weissman, I.L.2
  • 28
    • 69849099673 scopus 로고    scopus 로고
    • Biology of glioma cancer stem cells
    • Park DM, Rich JN. Biology of glioma cancer stem cells. Mol Cells 2009;28:7-12.
    • (2009) Mol Cells , vol.28 , pp. 7-12
    • Park, D.M.1    Rich, J.N.2
  • 29
    • 34547915240 scopus 로고    scopus 로고
    • Increased CK19 expression correlated with pathologic differentiation grade and prognosis in oral squamous cell carcinoma patients
    • Zhong LP, Chen WT, Zhang CP, et al. Increased CK19 expression correlated with pathologic differentiation grade and prognosis in oral squamous cell carcinoma patients. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;104:377-384.
    • (2007) Oral Surg Oral Med Oral Pathol Oral Radiol Endod , vol.104 , pp. 377-384
    • Zhong, L.P.1    Chen, W.T.2    Zhang, C.P.3
  • 30
    • 33745061991 scopus 로고    scopus 로고
    • Immuno-histological evaluation of Ki-67, p63, CK19 and p53 expression in oral epithelial dysplasias
    • Takeda T, Sugihara K, Hirayama Y, et al. Immuno-histological evaluation of Ki-67, p63, CK19 and p53 expression in oral epithelial dysplasias. J Oral Pathol Med 2006;35:369-375.
    • (2006) J Oral Pathol Med , vol.35 , pp. 369-375
    • Takeda, T.1    Sugihara, K.2    Hirayama, Y.3
  • 31
    • 0037377611 scopus 로고    scopus 로고
    • Pagetoid squamous cell carcinoma in situ (pagetoid Bowen's disease) of the external genitalia
    • Raju RR, Goldblum JR, Hart WR. Pagetoid squamous cell carcinoma in situ (pagetoid Bowen's disease) of the external genitalia. Int J Gynecol Pathol 2003;22: 127-135.
    • (2003) Int J Gynecol Pathol , vol.22 , pp. 127-135
    • Raju, R.R.1    Goldblum, J.R.2    Hart, W.R.3
  • 32
    • 51849121584 scopus 로고    scopus 로고
    • Increased expression of an epidermal stem cell marker, cytoker-atin 19, in cutaneous squamous cell carcinoma
    • Chen S, Takahara M, Kido M, et al. Increased expression of an epidermal stem cell marker, cytoker-atin 19, in cutaneous squamous cell carcinoma. Br J Dermatol 2008;159:952-955.
    • (2008) Br J Dermatol , vol.159 , pp. 952-955
    • Chen, S.1    Takahara, M.2    Kido, M.3
  • 33
    • 2442460066 scopus 로고    scopus 로고
    • Cytokeratin 17 and p63 are markers of the HPV target cell, the cervical stem cell
    • Martens JE, Arends J, Van der Linden PJ, et al. Cytokeratin 17 and p63 are markers of the HPV target cell, the cervical stem cell. Anticancer Res 2004;24: 771-775.
    • (2004) Anticancer Res , vol.24 , pp. 771-775
    • Martens, J.E.1    Arends, J.2    Van Der Linden, P.J.3
  • 34
    • 0034079520 scopus 로고    scopus 로고
    • The p53/ p63/p73 family of transcription factors: Overlapping and distinct functions
    • Levrero M, De Laurenzi V, Costanzo A, et al. The p53/ p63/p73 family of transcription factors: overlapping and distinct functions. J Cell Sci 2000;113:1661-1670.
    • (2000) J Cell Sci , vol.113 , pp. 1661-1670
    • Levrero, M.1    De Laurenzi, V.2    Costanzo, A.3
  • 36
    • 85047687455 scopus 로고    scopus 로고
    • Taking advantage of basic research: P63 is a reliable myoepithelial and stem cell marker
    • Reis-Filho JS, Schmitt FC. Taking advantage of basic research: p63 is a reliable myoepithelial and stem cell marker. Adv Anat Pathol 2002;9:280-289.
    • (2002) Adv Anat Pathol , vol.9 , pp. 280-289
    • Reis-Filho, J.S.1    Schmitt, F.C.2
  • 37
    • 0037257840 scopus 로고    scopus 로고
    • P63 expression in normal human epidermis and epidermal appendages and their tumors
    • Tsujita-Kyutoku M, Kiuchi K, Danbara N, et al. p63 expression in normal human epidermis and epidermal appendages and their tumors. J Cutan Pathol 2003;30: 11-17.
    • (2003) J Cutan Pathol , vol.30 , pp. 11-17
    • Tsujita-Kyutoku, M.1    Kiuchi, K.2    Danbara, N.3
  • 38
    • 7044285759 scopus 로고    scopus 로고
    • The expression of p63 in actinic keratoses, seborrheic keratosis, and cutaneous squamous cell carcinomas
    • Wrone DA, Yoo S, Chipps LK, Moy RL. The expression of p63 in actinic keratoses, seborrheic keratosis, and cutaneous squamous cell carcinomas. Dermatol Surg 2004;30:1299-1302.
    • (2004) Dermatol Surg , vol.30 , pp. 1299-1302
    • Wrone, D.A.1    Yoo, S.2    Chipps, L.K.3    Moy, R.L.4
  • 39
    • 33744976087 scopus 로고    scopus 로고
    • P63 is a useful marker for cutaneous spindle cell squamous cell carcinoma
    • Dotto JE, Glusac EJ. p63 is a useful marker for cutaneous spindle cell squamous cell carcinoma. J Cutan Pathol 2006;33:413-417.
    • (2006) J Cutan Pathol , vol.33 , pp. 413-417
    • Dotto, J.E.1    Glusac, E.J.2
  • 40
    • 32244432504 scopus 로고    scopus 로고
    • The pluripotency of hair follicle stem cells
    • Hoffman RM. The pluripotency of hair follicle stem cells. Cell Cycle 2006;5:232-233.
    • (2006) Cell Cycle , vol.5 , pp. 232-233
    • Hoffman, R.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.