Kinetic intermediates of β2-microglobulin fibril elongation probed by pulse-labeling H/D exchange combined with NMR analysis

Journal of Molecular Biology

Volumn 405, Issue 3, 2011, Pages 851-862

  Konuma, Tsuyoshi ^a   Chatani, Eri ^a,c   Yagi, Masanori ^a   Sakurai, Kazumasa ^a   Ikegami, Takahisa ^a   Naiki, Hironobu ^b   Goto, Yuji ^a  

^a OSAKA UNIVERSITY   (Japan)

^b UNIVERSITY OF FUKUI   (Japan)

^c RITSUMEIKAN UNIVERSITY   (Japan)

Author keywords

dialysis related amyloidosis; intermediate of fibril elongation; NMR spectroscopy; protein misfolding; pulse labeling H D exchange

Indexed keywords

BETA 2 MICROGLOBULIN; MONOMER; NITROGEN 15;

ARTICLE; CHEMICAL REACTION KINETICS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DEUTERIUM HYDROGEN EXCHANGE; HYDROPHOBICITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN INTERACTION;

EID: 78650909852     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2010.11.029     Document Type: Article

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