Endoplasmic reticulum stress markers and ubiquitin-proteasome pathway activity in response to a 200-km run

Medicine and Science in Sports and Exercise

Volumn 43, Issue 1, 2011, Pages 18-25

  Kim, Hyo Jeong ^a   Jamart, Céicile ^b   Deldicque, Louise ^b   An, Gang Li ^b   Lee, Yoon Hee ^a   Kim, Chang Keun ^a   Raymackers, Jean Marc ^b   Francaux, Marc ^b  

^a Korea National Sport University   (South Korea)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

BiP GRP78; inflammation; oxidative stress; ubiquitin ligases; ultraendurance; XBP1

Indexed keywords

BIOLOGICAL MARKER; DNA BINDING PROTEIN; FBXO32 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE; MUSCLE PROTEIN; PROTEASOME; PROTEIN KINASE; RING1 PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE;

ADULT; ARTICLE; BIOPSY; BIOSYNTHESIS; ENDOPLASMIC RETICULUM; FLUOROMETRY; HUMAN; INFLAMMATION; MALE; METABOLISM; MIDDLE AGED; OXIDATIVE STRESS; PATHOLOGY; PHYSIOLOGICAL STRESS; PHYSIOLOGY; QUADRICEPS FEMORIS MUSCLE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RUNNING; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ADULT; BIOLOGICAL MARKERS; BIOPSY; BLOTTING, WESTERN; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM; FLUOROMETRY; HUMANS; INFLAMMATION; MALE; MAP KINASE SIGNALING SYSTEM; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE PROTEINS; OXIDATIVE STRESS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN KINASES; QUADRICEPS MUSCLE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RUNNING; SIGNAL TRANSDUCTION; SKP CULLIN F-BOX PROTEIN LIGASES; STRESS, PHYSIOLOGICAL; UBIQUITIN-PROTEIN LIGASE COMPLEXES;

EID: 78650899028     PISSN: 01959131     EISSN: 15300315     Source Type: Journal    
DOI: 10.1249/MSS.0b013e3181e4c5d1     Document Type: Article

References (40)

1. Bodine SC, Latres E, Baumhueter S, et al. Identification of ubiquitin ligases required for skeletal muscle atrophy. Science. 2001;294(5547):1704-8.
2. Brozinick JT Jr, Birnbaum MJ. Insulin, but not contraction, activates Akt/PKB in isolated rat skeletal muscle. J Biol Chem. 1998; 273(24):14679-82.
3. Crenshaw AG, Friden J, Hargens AR, Lang GH, Thornell LE. Increased technetium uptake is not equivalent to muscle necrosis: scintigraphic, morphological and intramuscular pressure analyses of sore muscles after exercise. Acta Physiol Scand. 1993;148(2): 187-98.
4. Davies CT, Thompson MW. Physiological responses to prolonged exercise in ultramarathon athletes. J Appl Physiol. 1986;61(2): 611-7.
5. Deldicque L, Atherton P, Patel R, et al. Effects of resistance exercise with and without creatine supplementation on gene expression and cell signaling in human skeletal muscle. J Appl Physiol. 2008;104(2):371-8.
6. Dohm GL, Tapscott EB, Kasperek GJ. Protein degradation during endurance exercise and recovery. Med Sci Sports Exerc. 1987; 19(5 suppl):S166-71.
7. Farout L, Lamare MC, Cardozo C, Harrisson M, Briand Y, Briand M. Distribution of proteasomes and of the five proteolytic activities in rat tissues. Arch Biochem Biophys. 2000;374(2): 207-12.
8. Hirota M, Kitagaki M, Itagaki H, Aiba S. Quantitative measurement of spliced XBP1 mRNA as an indicator of endoplasmic reticulum stress. J Toxicol Sci. 2006;31(2):149-56.
9. 2+- signaling complexes and Ca2+ regulation in secretory and muscle cells from PERK-knockout mice. J Cell Sci. 2006;119( pt 1):153-61.
10. Ishii T, Sakurai T, Usami H, Uchida K. Oxidative modification of proteasome: identification of an oxidation-sensitive subunit in 26 S proteasome. Biochemistry. 2005;44(42):13893-901.
11. Kim HJ, Lee YH, Kim CK. Biomarkers of muscle and cartilage damage and inflammation during a 200 km run. Eur J Appl Physiol. 2007;99(4):443-7.
12. Koulmann N, Bigard AX. Interaction between signalling pathways involved in skeletal muscle responses to endurance exercise. Pflugers Arch. 2006;452(2):125-39.
13. Mahoney DJ, Parise G, Melov S, Safdar A, Tarnopolsky MA. Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise. FASEB J. 2005;19(11): 1498-500.
14. Mastaloudis A, Leonard SW, Traber MG. Oxidative stress in athletes during extreme endurance exercise. Free Radic Biol Med. 2001;31(7):911-22.
15. Mastaloudis A, Traber MG, Carstensen K, Widrick JJ. Antioxidants did not prevent muscle damage in response to an ultramarathon run. Med Sci Sports Exerc. 2006;38(1):72-80.
16. McGee SL, Hargreaves M. Exercise and myocyte enhancer factor 2 regulation in human skeletal muscle. Diabetes. 2004;53(5):1208-14.
17. Merksamer PI, Trusina A, Papa FR. Real-time redox measurements during endoplasmic reticulum stress reveal interlinked protein folding functions. Cell. 2008;135(5):933-47.
18. Murton AJ, Constantin D, Greenhaff PL. The involvement of the ubiquitin proteasome system in human skeletal muscle remodelling and atrophy. Biochim Biophys Acta. 2008;1782(12):730-43.
19. Nedergaard A, Vissing K, Overgaard K, Kjaer M, Schjerling P. Expression patterns of atrogenic and ubiquitin proteasome component genes with exercise: effect of different loading patterns and repeated exercise bouts. J Appl Physiol. 2007;103(5):1513-22.
20. Nielsen AR, Pedersen BK. The biological roles of exerciseinduced cytokines: IL-6, IL-8, and IL-15. Appl Physiol Nutr Metab. 2007;32(5):833-9.
21. Nieman DC, Davis JM, Brown VA, et al. Influence of carbohydrate ingestion on immune changes after 2 h of intensive resistance training. J Appl Physiol. 2004;96(4):1292-8.
22. Nieman DC, Henson DA, Davis JM, et al. Quercetin ingestion does not alter cytokine changes in athletes competing in the Western States Endurance Run. J Interferon Cytokine Res. 2007; 27(12):1003-11.
23. Nieman DC, Henson DA, Dumke CL, et al. Ibuprofen use, endotoxemia, inflammation, and plasma cytokines during ultramarathon competition. Brain Behav Immun. 2006;20(6):578-84.
24. Ostrowski K, Rohde T, Zacho M, Asp S, Pedersen BK. Evidence that interleukin-6 is produced in human skeletal muscle during prolonged running. J Physiol. 1998;508( pt 3):949-53.
25. Ozcan U, Cao Q, Yilmaz E, et al. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science. 2004; 306(5695):457-61.
26. Papassotiriou I, Alexiou VG, Tsironi M, Skenderi K, Spanos A, Falagas ME. Severe aseptic inflammation caused by long distance running (246 km) does not increase procalcitonin. Eur J Clin Invest. 2008;38(4):276-9.
27. Penkowa M, Keller P, Keller C, Hidalgo J, Giralt M, Pedersen BK. Exercise-induced metallothionein expression in human skeletal muscle fibres. Exp Physiol. 2005;90(4):477-86.
28. Peter A, Weigert C, Staiger H, et al. Individual stearoyl-CoA desaturase 1 expression modulates endoplasmic reticulum stress and inflammation in human myotubes and is associated with skeletal muscle lipid storage and insulin sensitivity in vivo. Diabetes. 2009; 58(8):1757-65.
29. Petersen AM, Pedersen BK. The anti-inflammatory effect of exercise. J Appl Physiol. 2005;98(4):1154-62.
30. Reid MB. Response of the ubiquitin-proteasome pathway to changes in muscle activity. Am J Physiol Regul Integr Comp Physiol. 2005;288(6):R1423-31.
31. Roberts CK, Barnard RJ, Sindhu RK, Jurczak M, Ehdaie A, Vaziri ND. Oxidative stress and dysregulation of NAD(P)H oxidase and antioxidant enzymes in diet-induced metabolic syndrome. Metabolism. 2006;55(7):928-34.
32. Ron D, Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol. 2007;8(7): 519-29.
33. Sahlin K, Shabalina IG, Mattsson CM, et al. Ultra-endurance exercise increases the production of reactive oxygen species in isolated mitochondria from human skeletal muscle. J Appl Physiol. 2010;108(4):780-7.
34. Starkie R, Ostrowski SR, Jauffred S, Febbraio M, Pedersen BK. Exercise and IL-6 infusion inhibit endotoxin-induced TNF-alpha production in humans. Faseb J. 2003;17(8):884-6.
35. van der Vlies D, Makkinje M, Jansens A, et al. Oxidation of ER resident proteins upon oxidative stress: effects of altering cellular redox/antioxidant status and implications for protein maturation. Antioxid Redox Signal. 2003;5(4):381-7.
36. Vembar SS, Brodsky JL. One step at a time: endoplasmic reticulum- associated degradation. Nat Rev Mol Cell Biol. 2008;9(12):944-57.
37. Wing SS. Control of ubiquitination in skeletal muscle wasting. Int J Biochem Cell Biol. 2005;37(10):2075-87.
38. Witt SH, Granzier H, Witt CC, Labeit S. MURF-1 and MURF-2 target a specific subset of myofibrillar proteins redundantly: towards understanding MURF-dependent muscle ubiquitination. J Mol Biol. 2005;350(4):713-22.
39. Wojtaszewski JF, Nielsen P, Kiens B, Richter EA. Regulation of glycogen synthase kinase-3 in human skeletal muscle: effects of food intake and bicycle exercise. Diabetes. 2001;50(2):265-9.
40. Yoshida H, Haze K, Yanagi H, Yura T, Mori K. Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucoseregulated proteins: involvement of basic leucine zipper transcription factors. J Biol Chem. 1998;273(50):33741-9.