Aromatase is a direct target of FOXl2: C134W in granulosa cell tumors via a single highly conserved binding site in the ovarian specific promoter

PLoS ONE

Volumn 5, Issue 12, 2010, Pages

  Fleming, Nicholas I ^a   Knower, Kevin C ^a   Lazarus, Kyren A ^a   Fuller, Peter J ^a,b   Simpson, Evan R ^a,b   Clyne, Colin D ^a,b  

^a HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATASE; MESSENGER RNA; STEROIDOGENIC ACUTE REGULATORY PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXL2; UNCLASSIFIED DRUG; FORKHEAD TRANSCRIPTION FACTOR; FOXL2 PROTEIN, HUMAN; PHOSPHOPROTEIN;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; GEL MOBILITY SHIFT ASSAY; GRANULOSA CELL TUMOR; HETEROZYGOSITY; HUMAN; HUMAN CELL; MUTATION; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; SITE DIRECTED MUTAGENESIS; TRANSCRIPTION INITIATION; FEMALE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; OVARY TUMOR; POINT MUTATION; REGULATORY SEQUENCE; TUMOR CELL LINE;

AROMATASE; BINDING SITES; CELL LINE, TUMOR; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; GRANULOSA CELL TUMOR; HUMANS; MUTAGENESIS, SITE-DIRECTED; MUTATION; OVARIAN NEOPLASMS; PHOSPHOPROTEINS; POINT MUTATION; PROMOTER REGIONS, GENETIC; REGULATORY SEQUENCES, NUCLEIC ACID;

EID: 78650864795     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0014389     Document Type: Article

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