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Volumn 10, Issue 1, 2011, Pages 127-134

Ubiquitin-mediated protein degradation and methylation-induced gene silencing cooperate in the inactivation of the INK4/ARF locus in Burkitt's lymphoma cell lines

Author keywords

Burkitt's lymphoma; INK4a ARF locus; Proteasome inhibitors; Ubiquitin proteasome system (UPS)

Indexed keywords

ARF PROTEIN; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CYCLIN DEPENDENT KINASE INHIBITOR 2A; PROTEASOME; UBIQUITIN;

EID: 78650840614     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.10.1.14446     Document Type: Article
Times cited : (21)

References (29)
  • 1
    • 40149101566 scopus 로고    scopus 로고
    • The role of environmental factors in the etiology of lymphoma
    • Blinder V, Fisher SG. The role of environmental factors in the etiology of lymphoma. Cancer Invest 2008; 26:306-16.
    • (2008) Cancer Invest , vol.26 , pp. 306-316
    • Blinder, V.1    Fisher, S.G.2
  • 3
    • 0034327890 scopus 로고    scopus 로고
    • Molecular biology of Burkitt's lymphoma
    • Hecht JL, Aster JC. Molecular biology of Burkitt's lymphoma. J Clin Oncol 2000; 18:3707-21.
    • (2000) J Clin Oncol , vol.18 , pp. 3707-3721
    • Hecht, J.L.1    Aster, J.C.2
  • 4
    • 54949149565 scopus 로고    scopus 로고
    • Apoptotic signaling by c-MYC
    • Hoffman B, Liebermann DA. Apoptotic signaling by c-MYC. Oncogene 2008; 27:6462-72.
    • (2008) Oncogene , vol.27 , pp. 6462-6472
    • Hoffman, B.1    Liebermann, D.A.2
  • 5
    • 77950092933 scopus 로고    scopus 로고
    • Transcription-independent ARF regulation in oncogenic stress-mediated p53 responses
    • Chen D, Shan J, Zhu WG, Qin J, Gu W. Transcription-independent ARF regulation in oncogenic stress-mediated p53 responses. Nature 464:624-7.
    • Nature , vol.464 , pp. 624-627
    • Chen, D.1    Shan, J.2    Zhu, W.G.3    Qin, J.4    Gu, W.5
  • 6
    • 0035912061 scopus 로고    scopus 로고
    • ARF homozygous deletion or MDM2 overexpression in Burkitt lymphoma lines carrying wild type p53
    • ARF homozygous deletion or MDM2 overexpression in Burkitt lymphoma lines carrying wild type p53. Oncogene 2001; 20:2171-7.
    • (2001) Oncogene , vol.20 , pp. 2171-2177
    • Lindstrom, M.S.1    Klangby, U.2    Wiman, K.G.3
  • 7
    • 33645792588 scopus 로고    scopus 로고
    • Burkitt's lymphoma: Clinicopathologic features and differential diagnosis
    • Ferry JA. Burkitt's lymphoma: Clinicopathologic features and differential diagnosis. Oncologist 2006; 11:375-83.
    • (2006) Oncologist , vol.11 , pp. 375-383
    • Ferry, J.A.1
  • 8
    • 0022380768 scopus 로고
    • The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice
    • Adams JM, Harris AW, Pinkert CA, Corcoran LM, Alexander WS, Cory S, et al. The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice. Nature 1985; 318:533-8.
    • (1985) Nature , vol.318 , pp. 533-538
    • Adams, J.M.1    Harris, A.W.2    Pinkert, C.A.3    Corcoran, L.M.4    Alexander, W.S.5    Cory, S.6
  • 9
    • 0028046245 scopus 로고
    • Apoptosis and macrophage-mediated deletion of precursor B cells in the bone marrow of e mu-myc transgenic mice
    • Jacobsen KA, Prasad VS, Sidman CL, Osmond DG. Apoptosis and macrophage-mediated deletion of precursor B cells in the bone marrow of E mu-myc transgenic mice. Blood 1994; 84:2784-94.
    • (1994) Blood , vol.84 , pp. 2784-2794
    • Jacobsen, K.A.1    Prasad, V.S.2    Sidman, C.L.3    Osmond, D.G.4
  • 10
    • 0033569422 scopus 로고    scopus 로고
    • Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis
    • Eischen CM, Weber JD, Roussel MF, Sherr CJ, Cleveland JL. Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis. Genes Dev 1999; 13:2658-69.
    • (1999) Genes Dev , vol.13 , pp. 2658-2669
    • Eischen, C.M.1    Weber, J.D.2    Roussel, M.F.3    Sherr, C.J.4    Cleveland, J.L.5
  • 12
    • 22144489899 scopus 로고    scopus 로고
    • INK4a/ARF: A multifunctional tumor suppressor locus
    • Sharpless NE. INK4a/ARF: A multifunctional tumor suppressor locus. Mutat Res 2005; 576:22-38.
    • (2005) Mutat Res , vol.576 , pp. 22-38
    • Sharpless, N.E.1
  • 13
  • 14
    • 0027769876 scopus 로고
    • A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano M, Hannon GJ, Beach D. A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4. Nature 1993; 366:704-7.
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 15
    • 0032517341 scopus 로고    scopus 로고
    • INK4a/CDKN2A tumor suppressor and its relatives
    • INK4a/CDKN2A tumor suppressor and its relatives. Biochim Biophys Acta 1998; 1378:115-77.
    • (1998) Biochim Biophys Acta , vol.1378 , pp. 115-177
    • Ruas, M.1    Peters, G.2
  • 16
    • 0035823031 scopus 로고    scopus 로고
    • Parsing Ink4a/Arf: "Pure" p16-null mice
    • Sherr CJ. Parsing Ink4a/Arf: "Pure" p16-null mice. Cell 2001; 106:531-4.
    • (2001) Cell , vol.106 , pp. 531-534
    • Sherr, C.J.1
  • 17
    • 33748356697 scopus 로고    scopus 로고
    • Establishment and characterisation of two novel human KSHV- And EBV-negative Burkitt cell lines, GAL-01 and GAL-02, from a primary lymphomatous effusion
    • Thielen C, Herens C, Fassotte MF, Detrooz E, Drion P, Diss T, et al. Establishment and characterisation of two novel human KSHV- and EBV-negative Burkitt cell lines, GAL-01 and GAL-02, from a primary lymphomatous effusion. Eur J Haematol 2006; 77:318-26.
    • (2006) Eur J Haematol , vol.77 , pp. 318-326
    • Thielen, C.1    Herens, C.2    Fassotte, M.F.3    Detrooz, E.4    Drion, P.5    Diss, T.6
  • 18
    • 0032030648 scopus 로고    scopus 로고
    • P16/INK4a and p15/INK4b gene methylation and absence of p16/INK4a mRNA and protein expression in Burkitt's lymphoma
    • Klangby U, Okan I, Magnusson KP, Wendland M, Lind P, Wiman KG. p16/INK4a and p15/INK4b gene methylation and absence of p16/INK4a mRNA and protein expression in Burkitt's lymphoma. Blood 1998; 91:1680-7.
    • (1998) Blood , vol.91 , pp. 1680-1687
    • Klangby, U.1    Okan, I.2    Magnusson, K.P.3    Wendland, M.4    Lind, P.5    Wiman, K.G.6
  • 19
    • 0032145569 scopus 로고    scopus 로고
    • Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization
    • Zindy F, Eischen CM, Randle DH, Kamijo T, Cleveland JL, Sherr CJ, et al. Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization. Genes Dev 1998; 12:2424-33.
    • (1998) Genes Dev , vol.12 , pp. 2424-2433
    • Zindy, F.1    Eischen, C.M.2    Randle, D.H.3    Kamijo, T.4    Cleveland, J.L.5    Sherr, C.J.6
  • 22
    • 0036392058 scopus 로고    scopus 로고
    • Role of genetic and epigenetic changes in Burkitt lymphoma
    • Lindstrom MS, Wiman KG. Role of genetic and epigenetic changes in Burkitt lymphoma. Semin Cancer Biol 2002; 12:381-7.
    • (2002) Semin Cancer Biol , vol.12 , pp. 381-387
    • Lindstrom, M.S.1    Wiman, K.G.2
  • 23
    • 0034059667 scopus 로고    scopus 로고
    • C-Myc proteolysis by the ubiquitin-proteasome pathway: Stabilization of c-Myc in Burkitt's lymphoma cells
    • Gregory MA, Hann SR. c-Myc proteolysis by the ubiquitin-proteasome pathway: stabilization of c-Myc in Burkitt's lymphoma cells. Mol Cell Biol 2000; 20:2423-35.
    • (2000) Mol Cell Biol , vol.20 , pp. 2423-2435
    • Gregory, M.A.1    Hann, S.R.2
  • 25
    • 3543148255 scopus 로고    scopus 로고
    • N-terminal polyubiquitination and degradation of the Arf tumor suppressor
    • Kuo ML, den Besten W, Bertwistle D, Roussel MF, Sherr CJ. N-terminal polyubiquitination and degradation of the Arf tumor suppressor. Genes Dev 2004; 18:1862-74.
    • (2004) Genes Dev , vol.18 , pp. 1862-1874
    • Kuo, M.L.1    Den Besten, W.2    Bertwistle, D.3    Roussel, M.F.4    Sherr, C.J.5
  • 26
    • 4744371446 scopus 로고    scopus 로고
    • The tumor suppressor protein p16(INK4a) and the human papillomavirus oncoprotein-58 E7 are naturally occurring lysine-less proteins that are degraded by the ubiquitin system. Direct evidence for ubiquitination at the N-terminal residue
    • Ben-Saadon R, Fajerman I, Ziv T, Hellman U, Schwartz AL, Ciechanover A. The tumor suppressor protein p16(INK4a) and the human papillomavirus oncoprotein-58 E7 are naturally occurring lysine-less proteins that are degraded by the ubiquitin system. Direct evidence for ubiquitination at the N-terminal residue. J Biol Chem 2004; 279:41414-21.
    • (2004) J Biol Chem , vol.279 , pp. 41414-41421
    • Ben-Saadon, R.1    Fajerman, I.2    Ziv, T.3    Hellman, U.4    Schwartz, A.L.5    Ciechanover, A.6
  • 27
    • 0036348365 scopus 로고    scopus 로고
    • Proteasome inhibitors in the treatment of B-cell malignancies
    • Schenkein D. Proteasome inhibitors in the treatment of B-cell malignancies. Clin Lymphoma 2002; 3:49-55.
    • (2002) Clin Lymphoma , vol.3 , pp. 49-55
    • Schenkein, D.1
  • 29
    • 33747611439 scopus 로고    scopus 로고
    • Restoration of shp1 expression by 5-AZA-2′-deoxycytidine is associated with downregulation of JAK3/STAT3 signaling in ALK-positive anaplastic large cell lymphoma
    • Han Y, Amin HM, Frantz C, Franko B, Lee J, Lin Q, et al. Restoration of shp1 expression by 5-AZA-2′-deoxycytidine is associated with downregulation of JAK3/STAT3 signaling in ALK-positive anaplastic large cell lymphoma. Leukemia 2006; 20:1602-9.
    • (2006) Leukemia , vol.20 , pp. 1602-1609
    • Han, Y.1    Amin, H.M.2    Frantz, C.3    Franko, B.4    Lee, J.5    Lin, Q.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.