Chemical states of the N-terminal "lid" of MDM2 regulate p53 binding: Simulations reveal complexities of modulation

Cell Cycle

Volumn 10, Issue 1, 2011, Pages 82-89

  Dastidar, Shubhra Ghosh ^a   Raghunathan, Devanathan ^a   Nicholson, Judith ^c   Hupp, Ted R ^c   Lane, David P ^b   Verma, Chandra S ^a  

^a BIOINFORMATICS INSTITUTE   (Singapore)

^b AGENCY FOR SCIENCE   (Singapore)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

MD simulation; MDM2; N terminal lid; p53 regulation; Phosphorylation

Indexed keywords

PROTEIN MDM2; PROTEIN P53;

ARTICLE; NUCLEAR MAGNETIC RESONANCE; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION;

EID: 78650805323     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.10.1.14345     Document Type: Article

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