Retinoids: Mechanisms of action;Rétinoïdes: Mécanismes d'action

Annales de Dermatologie et de Venereologie

Volumn 137, Issue SUPPL. 3, 2010, Pages

  Berbis, P ^a,b  

^a HÔPITAL NORD   (France)

^b AIX MARSEILLE UNIVERSITY   (France)

Author keywords

Ligands; Metabolism; Nuclear receptors; Retinoids

Indexed keywords

ADAPALENE; ALITRETINOIN; BEXAROTENE; CYTOCHROME P450; ETRETIN; ISOTRETINOIN; RETINOID A RECEPTOR; RETINOID X RECEPTOR; TAZAROTENE; UNCLASSIFIED DRUG; VITAMIN RECEPTOR;

ARTICLE; DNA BINDING; DRUG MECHANISM; GENE EXPRESSION REGULATION; GENE TARGETING; HUMAN; LIGAND BINDING; TRANSCRIPTION INITIATION;

APOPTOSIS; CELL DIFFERENTIATION; CELL DIVISION; CYTOCHROME P-450 ENZYME SYSTEM; GENE EXPRESSION REGULATION; HUMANS; LIGANDS; PROTEIN MULTIMERIZATION; RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; RETINOIDS; SKIN; TRANSCRIPTIONAL ACTIVATION; TRETINOIN;

EID: 78650746920     PISSN: 01519638     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0151-9638(10)70036-3     Document Type: Article

References (47)

1. A.B. Barua, and N. Sidell Retinoyl beta-glucuronide: a biologically active interesting retinoid J Nutr 134 2004 286S 289S
2. R. Kawaguchi, J. Yu, J. Honda, J. Hu, J. Whitelegge, and P. Ping A membrane receptor for retinol binding protein mediates cellular uptake of vitamin A Science 315 2007 820 825
3. N.P. Mongan, and L.J. Gudas Diverse actions of retinoid receptors in cancer prevention and treatment Differentiation 75 2007 853 870
4. V. Jurukovski, N.G. Markova, N. Karaman-Jurukovska, R.K. Randolph, J. Su, and J.L. Napoli Cloning and characterization of retinol dehydrogenase transcripts expressed in human epidermal keratinocytes Mol Genet Metab 67 1999 62 73
5. X. Hébuterne, X.D. Wang, D.E. Smith, G. Tang, and R.M. Russell In vivo biosynthesis of retinoic acid from beta-carotene involves and excentric cleavage pathway in ferret intestine J Lipid Res 37 1996 482 492
6. H. Törmä, W. Löntz, W. Liu, O. Rollman, and A. Vahlquist Expression of cytosolic retinoid-binding protein genes in human skin biopsies and cultured keratinocytes and fibroblasts Br J Dermatol 131 1994 243 249
7. D. Chatellard-Gruaz, R.K. Randolph, G. Hagens, J.H. Saurat, and G. Siegenthaler Differentiation of human epidermal keratinocytes is accompanied by increased expression of CRABP-II and increased cellular concentration of retinoic acids : retention of newly synthesized retinoic acids by CRABP-II J Lipid Res 39 1998 1421 1429
8. J.F. Boylan, and L.J. Gudas The level of CRABP-I expression influences the amounts and types of all-trans-retinoic acid metabolites in F9 teratocarcinoma stem cells J Biol Chem 267 1992 21486 21491
9. A. Budhu, R. Gillilan, and N. Noy Localization of the RAR interaction domain of cellular retinoic acid binding protein-II J Mol Biol 305 2001 939 949
10. J. Abu, M. Batuwangala, K. Herbert, and P. Symonds Retinoic acid and retinoid receptors: potential chemopreventive and therapeutic role in cervical cancer Lancet Oncol 6 2005 712 720
11. A.R. Moise, N. Noy, K. Palczewski, and W.S. Blaner Delivery of retinoid-based therapies to target tissues Biochemistry 46 2007 4449 4458
12. M. Petkovich, N.J. Brand, A. Krust, and P. Chambon A human retinoic acid receptor which belongs to the family of nuclear receptors Nature 330 1987 444 450
13. V. Giguere, E.S. Ong, P. Segui, and R.M. Evans Identification of a receptor for the morphogen retinoic acid Nature 330 1987 624 629
14. A. Szanto, V. Narkar, Q. Shen, I.P. Uray, P.J. Davies, L. Nagy, and Retinoid X receptors : X-ploring their (patho) physiological functions Cell Death Differ 11 Suppl 2 2004 S126 S143
15. M.E. Swift, B. Wallden, E.A. Wayner, and K. Swisshelm Truncated RAR beta isoform enhances proliferation and retinoid resistance J Cell Physiol 209 2006 718 725
16. D.L. Bain, A.F. Heneghan, K.D. Connaghan-Jones, and M.T. Miura Nuclear receptor structure : implications for function Annu Rev Physiol 69 2007 201 220
17. P.C. van de Kerkhof Update on retinoid therapy of psoriasis in : an update on the use of retinoids in dermatology Dermatol, Ther 19 2006 252 263
18. G. Li, E. Walch, X. Yang, S.M. Lippman, and J.L. Clifford Cloning and characterization of the human retinoid X receptor alpha gene: conservation of structure with the mouse homolog Biochem Biophys Res Commun 269 2000 54 57
19. P. Kastner, A. Krust, C. Mendelsohn, J.M. Garnier, A. Zelent, and P. Leroy Murine isoforms of retinoic acid receptor gamma with specific patterns of expression Proc Natl Acad Sci U S A 87 1990 2700 2704
20. Fan J, Eastham L, Varney M, Hall A, Adkins NL, Sollars V, et al. Silencing and re-expression of retinoic acid receptor beta2 in human melanoma. Pigment Cell Melanoma Res 2010 [in press]
21. M. Li, H. Chiba, X. Warot, N. Messaddeq, C. Gérard, and P. Chambon RXR-alpha ablation in skin keratinocytes results in alopecia and epidermal alterations Development 128 2001 675 688
22. B. Chapellier, M. Mark, N. Messaddeq, C. Calléja, X. Warot, and J. Brocard Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled EMBO J 21 2002 3402 3413
23. A.M. Standeven, M. Teng, and R.A. Chandraratna Lack of involvement of retinoic acid receptor alpha in retinoid-induced skin irritation in hairless mice Toxicol Lett 92 1997 231 240
24. C. Rochette-Egly, and P. Germain Dynamic and combinatorial control of gene expression by nuclear retinoic acid receptors (RARs) Nucl Recept Signal 7 2009 e005
25. P. Chambon A decade of molecular biology of retinoic acid receptors FASEB J 10 1996 940 954
26. C. Zechel, X.Q. Shen, P. Chambon, and H. Gronemeyer Dimerization interfaces formed between the DNA binding domains determine the cooperative binding of RXR/RAR and RXR/TR heterodimers to DR5 and DR4 elements EMBO J 13 1994 1414 1424
27. J. Bastien, and C. Rochette-Egly Nuclear retinoid receptors and the transcription of retinoid-target genes Gene 328 2004 1 16
28. M.M. Poon, and L. Chen Retinoic acid-gated sequence-specific translational control by RARalpha Proc Natl Acad Sci U S A 105 2008 20303 20308
29. M. Leid, P. Kastner, R. Lyons, H. Nakshatri, M. Saunders, and T. Zacharewski Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently Cell 68 1992 377 395
30. J. Brtko Retinoids, rexinoids and their cognate nuclear receptors: character and their role in chemoprevention of selected malignant diseases Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 151 2007 187 194
31. J.E. Balmer, and R. Blomhoff A robust characterization of retinoic acid response elements based on a comparison of sites in three species J Steroid Biochem Mol Biol 96 2005 347 354
32. A.J. Hörlein, A.M. Näär, T. Heinzel, J. Torchia, B. Gloss, and R. Kurokawa Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor Nature 377 1995 397 404
33. D. Moras, and H. Gronemeyer The nuclear receptor ligand-binding domain: structure and function Curr Opin Cell Biol 10 1998 384 391
34. M. Giann, A. Bauer, E. Garattini, P. Chambon, and C. Rochette-Egly Phosphorylation by p38MAPK and recruitment of SUG-1 are required for RA-induced RAR gamma degradation and transactivation EMBO J 21 2002 3760 3769
35. R. Blomhoff, and H.K. Blomhoff Overview of retinoid metabolism and function J Neurobiol 66 2006 606 630
36. A.L. Fields, D.R. Soprano, and K.J. Soprano Retinoids in biological control and cancer J Cell Biochem 102 2007 886 898
37. M. Giann, E. Parrella, I. Raska Jr., E. Gaillard, E.A. Nigro, and C. Gaudon P38MAPK-dependent phosphorylation and degradation of SRC-3/AIB1 and RARalpha-mediated transcription EMBO J 25 2006 739 751
38. N. Chen, B. Onisko, and J.L. Napoli The nuclear transcription factor RARalpha associates with neuronal RNA granules and suppresses translation J Biol Chem 283 2008 20841 20847
39. J.A. White, B. Beckett-Jones, Y.D. Guo, F.J. Dilworth, J. Bonasoro, and G. Jones cDNA cloning of human retinoic acidmetabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450 J Biol Chem 272 1997 18538 18541
40. J.A. White, H. Ramshaw, M. Taimi, W. Stangle, A. Zhang, and S. Everingham Identification of the human cytochrome P450 P450RAI-2, which is predominantly expressed in the adult cerebellum and is responsible for all-trans-retinoic acid metabolism Proc Natl Acad Sci U S A 97 2000 6403 6408
41. M. Taimi, C. Helvig, J. Wisniewski, H. Ramshaw, J. White, and M. Amad A novel human cytochrome P450 CYP26C1, involved in metabolism of 9-cis and all-trans isomers of retinoic acid J Biol Chem 279 2004 77 85
42. G.P. Lucker, C.J. Verfaille, A.M. Heremans, F.P. Vanhoutte, J.P. Boegheim, and P.P. Steijlen Topical liarozole in ichthyosis : a double-blind, left-right comparative study followed by a longterm open maintenance study Br J Dermatol 152 2005 566 569
43. C.J. Verfaille, F.P. Vanhoutte, C. Blanchet-Bardon, M.A. van Steensel, and P.M. Steijlen Oral liarozole vs. acitretin in the treatment of ichthyosis : a phase II/III multicentre, double-blind, randomized, active-controlled study Br J Dermatol 156 2007 965 973
44. H.J. Bovenschen, M.E. Otero, A.M. Langewouters, I.M. van Vlijmen-Willems, D.W. van Rens, and M.M. Seyger Oral retinoic acid metabolism blocking agent Rambazole for plaque psoriasis: an immunohistochemical study Br J Dermatol 156 2007 263 270
45. A.L. Fields, D.R. Soprano, and K.J. Soprano Retinoids in biological control and cancer J Cell Biochem 102 2007 886 898
46. Berbis Ph. Rétinoïdes. Encyclopédie Médico-chirurgicale, 2009;98-938-A-10.
47. A. Jetten Retinoid-related orphan receptors (RORs): critical roles in development, immunity, circadian rythm, and cellular metabolism Nucl Recept Signal 7 2009 e003