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Volumn 2, Issue 1, 2010, Pages 361-374

Lubiprostone: Evaluation of the newest medication for the treatment of adult women with constipation-predominant irritable bowel syndrome

Author keywords

Functional bowel disorder; Large intestine; Therapy

Indexed keywords

ION TRANSPORT AFFECTING AGENT; LINACLOTIDE; LUBIPROSTONE; PLACEBO; PRUCALOPRIDE;

EID: 78650743393     PISSN: None     EISSN: 11791411     Source Type: Book Series    
DOI: 10.2147/IJWH.S4537     Document Type: Review
Times cited : (18)

References (90)
  • 1
    • 0036829091 scopus 로고    scopus 로고
    • Gender differences in irritable bowel syndrome
    • Chang L, Heitkemper MM. Gender differences in irritable bowel syndrome. Gastroenterology. 2002;123(5):1686-1701.
    • (2002) Gastroenterology , vol.123 , Issue.5 , pp. 1686-1701
    • Chang, L.1    Heitkemper, M.M.2
  • 2
    • 67649537590 scopus 로고    scopus 로고
    • An evidence-based systematic review on the management of irritable bowel syndrome
    • Brandt LJ, Chey WD, Foxx-Orenstein AE, et al. An evidence-based systematic review on the management of irritable bowel syndrome. Am J Gastroenterol. 2009;104 SUPPL 1:S8-S35.
    • (2009) Am J Gastroenterol , vol.104 , Issue.1 , pp. 8-35
    • Brandt, L.J.1    Chey, W.D.2    Foxx-Orenstein, A.E.3
  • 4
    • 0027185528 scopus 로고
    • U.S, Householder survey of functional gastrointestinal disorders. Prevalence, sociodemography and health impact
    • Drossman D, Li Z, Andruzzi E, et al. U.S, Householder survey of functional gastrointestinal disorders. Prevalence, sociodemography and health impact. Dig Dis Sci. 1993;38(9):1569-1580.
    • (1993) Dig Dis Sci , vol.38 , Issue.9 , pp. 1569-1580
    • Drossman, D.1    Li, Z.2    Andruzzi, E.3
  • 5
    • 0036147287 scopus 로고    scopus 로고
    • Functional gastrointestinal disorders in Canada: First population based survey using Rome II criteria with suggestions for improving the questionnaire
    • Thompson WG, Irvine EJ, Pare P, Ferrazzi S, Rance, L. Functional gastrointestinal disorders in Canada: first population based survey using Rome II criteria with suggestions for improving the questionnaire. Dig Dis Sci. 2002;47(1):225-235.
    • (2002) Dig Dis Sci , vol.47 , Issue.1 , pp. 225-235
    • Thompson, W.G.1    Irvine, E.J.2    Pare, P.3    Ferrazzi, S.4    Rance, L.5
  • 7
    • 33646189604 scopus 로고    scopus 로고
    • Gender, age, society, culture, and the patient's perspective in the functional gastrointestinal disorders
    • Chang L, Toner BB, Fukodo S, et al. Gender, age, society, culture, and the patient's perspective in the functional gastrointestinal disorders. Gastroenterology. 2006;130(5):1435-1446.
    • (2006) Gastroenterology , vol.130 , Issue.5 , pp. 1435-1446
    • Chang, L.1    Toner, B.B.2    Fukodo, S.3
  • 8
    • 0035985451 scopus 로고    scopus 로고
    • Gender differences in irritable bowel syndrome
    • Chial HJ, Camilleri M. Gender differences in irritable bowel syndrome. J Gender Specif Med. 2002;5(3):37-45.
    • (2002) J Gender Specif Med , vol.5 , Issue.3 , pp. 37-45
    • Chial, H.J.1    Camilleri, M.2
  • 9
    • 0025353812 scopus 로고
    • Epidemiology of irritable bowel syndrome in the United States
    • Sandler RS. Epidemiology of irritable bowel syndrome in the United States. Gastroenterology. 1990;99(2):409-415.
    • (1990) Gastroenterology , vol.99 , Issue.2 , pp. 409-415
    • Sandler, R.S.1
  • 10
    • 10644257329 scopus 로고    scopus 로고
    • Review article: Epidemiology and quality of life in functional gastrointestinal disorders
    • Chang L. Review article: epidemiology and quality of life in functional gastrointestinal disorders. Aliment Pharmacol Ther. 2004;20 SUPPL 7:S31-S39.
    • (2004) Aliment Pharmacol Ther , vol.20 , Issue.7 , pp. 31-39
    • Chang, L.1
  • 11
    • 0030900827 scopus 로고    scopus 로고
    • Irritable bowel syndrome: A technical review for practice guideline development
    • Drossman DA, Whitehead WE, Camilleri M. Irritable bowel syndrome: a technical review for practice guideline development. Gastroenterology. 1997;112(6):2120-2137.
    • (1997) Gastroenterology , vol.112 , Issue.6 , pp. 2120-2137
    • Drossman, D.A.1    Whitehead, W.E.2    Camilleri, M.3
  • 12
    • 34250804722 scopus 로고    scopus 로고
    • Costs of health care for irritable bowel syndrome, chronic constipation, functional diarrhea and functional abdominal pain
    • Nyrop KA, Palsson OS, Levy RL, et al. Costs of health care for irritable bowel syndrome, chronic constipation, functional diarrhea and functional abdominal pain. Aliment Pharmacol Ther. 2007;26(2):237-248.
    • (2007) Aliment Pharmacol Ther , vol.26 , Issue.2 , pp. 237-248
    • Nyrop, K.A.1    Palsson, O.S.2    Levy, R.L.3
  • 13
    • 33847296344 scopus 로고    scopus 로고
    • Primary care physicians consider onstipation as a severe and bothersome medical condition that negatively impacts patients' lives
    • abstract 724
    • Schiller LR, Dennis E, Toth G. Primary care physicians consider onstipation as a severe and bothersome medical condition that negatively impacts patients' lives [abstract 724]. Am J Gastroenterol. 2004;99 SUPPL:S234-S235.
    • (2004) Am J Gastroenterol , vol.99 , pp. 234-235
    • Schiller, L.R.1    Dennis, E.2    Toth, G.3
  • 14
    • 4644350985 scopus 로고    scopus 로고
    • Irritable bowel syndrome medications side effects survey
    • Lembo A. Irritable bowel syndrome medications side effects survey. J Clin Gastroenterol. 2004;38(9):776-781.
    • (2004) J Clin Gastroenterol , vol.38 , Issue.9 , pp. 776-781
    • Lembo, A.1
  • 15
    • 34147173976 scopus 로고    scopus 로고
    • Lubiprostone: A chloride channel activator
    • Lacy BE, Levy LC. Lubiprostone: a chloride channel activator. J Clin Gastroenterol. 2007;41(4):345-351.
    • (2007) J Clin Gastroenterol , vol.41 , Issue.4 , pp. 345-351
    • Lacy, B.E.1    Levy, L.C.2
  • 16
    • 65549109893 scopus 로고    scopus 로고
    • Lubiprostone: Chronic constipation and irritable bowel with constipation
    • Lacy BE, Chey WD. Lubiprostone: chronic constipation and irritable bowel with constipation. Expert Opin Pharmacother. 2009;10(1):143-152.
    • (2009) Expert Opin Pharmacother , vol.10 , Issue.1 , pp. 143-152
    • Lacy, B.E.1    Chey, W.D.2
  • 17
    • 69249105681 scopus 로고    scopus 로고
    • Activation of intestinal Cl- secretion by lubiprostone requires the cystic fibrosis transmembrane conductance regulator
    • Bijvelds MJ, Bot AG, Escher JC, De Jonge HR. Activation of intestinal Cl- secretion by lubiprostone requires the cystic fibrosis transmembrane conductance regulator. Gastroenterology. 2009;137(3):976-985.
    • (2009) Gastroenterology , vol.137 , Issue.3 , pp. 976-985
    • Bijvelds, M.J.1    Bot, A.G.2    Escher, J.C.3    de Jonge, H.R.4
  • 18
    • 78650752252 scopus 로고    scopus 로고
    • Emerging diagnostic and treatment strategies for irritable bowel syndrome
    • Chang L, Lacy BE, Quigley EMM, Schoenfeld PS. Emerging diagnostic and treatment strategies for irritable bowel syndrome. Gastroenterol Hepatol. 2008;4(10):1-22.
    • (2008) Gastroenterol Hepatol , vol.4 , Issue.10 , pp. 1-22
    • Chang, L.1    Lacy, B.E.2    Quigley, E.M.M.3    Schoenfeld, P.S.4
  • 19
    • 0036256067 scopus 로고    scopus 로고
    • Healthrelated quality of life associated with irritable bowel syndrome: Comparison with other chronic diseases
    • Frank L, Kleinman L, Rentz A, Ciesla G, Kim JJ, Zacker C. Healthrelated quality of life associated with irritable bowel syndrome: comparison with other chronic diseases. Clin Ther. 2002;24(4):674-689.
    • (2002) Clin Ther , vol.24 , Issue.4 , pp. 674-689
    • Frank, L.1    Kleinman, L.2    Rentz, A.3    Ciesla, G.4    Kim, J.J.5    Zacker, C.6
  • 20
    • 40949131857 scopus 로고    scopus 로고
    • Clinical trial clinical trial: Phase 2 study of lubiprostone for irritable bowel syndrome with constipation
    • Johanson JF, Drossman DA, Panas R, Wahle A, Ueno R. Clinical trial clinical trial: phase 2 study of lubiprostone for irritable bowel syndrome with constipation. Aliment Pharmacol Ther. 2008;27(8):685-696.
    • (2008) Aliment Pharmacol Ther , vol.27 , Issue.8 , pp. 685-696
    • Johanson, J.F.1    Drossman, D.A.2    Panas, R.3    Wahle, A.4    Ueno, R.5
  • 21
    • 33644915873 scopus 로고    scopus 로고
    • Effect of a laxative with and without tegaserod in adolescents with constipation predominant irritable bowel syndrome
    • Khoshoo V, Armstead C, Landry L. Effect of a laxative with and without tegaserod in adolescents with constipation predominant irritable bowel syndrome. Aliment Pharmacol Ther. 2006:23(1):191-196.
    • (2006) Aliment Pharmacol Ther , vol.23 , Issue.1 , pp. 191-196
    • Khoshoo, V.1    Armstead, C.2    Landry, L.3
  • 22
    • 46049111418 scopus 로고    scopus 로고
    • The Food and Drug Administration approves lubiprostone for irritable bowel syndrome with constipation
    • Lang, L. The Food and Drug Administration approves lubiprostone for irritable bowel syndrome with constipation. Gastroenterology. 2008;135(1):7.
    • (2008) Gastroenterology , vol.135 , Issue.1 , pp. 7
    • Lang, L.1
  • 23
    • 33646809790 scopus 로고    scopus 로고
    • Lubiprostone Viewpoints comment
    • Schiller LR, Camilleri M. Lubiprostone: viewpoints [comment]. Drugs. 2006;66(6):880-881.
    • (2006) Drugs , vol.66 , Issue.6 , pp. 880-881
    • Schiller, L.R.1    Camilleri, M.2
  • 24
    • 78650728261 scopus 로고    scopus 로고
    • ® (lubiprostone) [package insert]. Bethesda, MD: Sucampo Pharmaceuticals, Inc
    • ® (lubiprostone) [package insert]. Bethesda, MD: Sucampo Pharmaceuticals, Inc; 2009.
    • (2009)
  • 25
    • 33645574326 scopus 로고    scopus 로고
    • Lubiprostone A novel chloride channel activator for the treatment of constipation
    • Orr, KK. Lubiprostone: a novel chloride channel activator for the treatment of constipation. Formulary. 2006;41(3):118-129.
    • (2006) Formulary , vol.41 , Issue.3 , pp. 118-129
    • Orr, K.K.1
  • 26
    • 33645837674 scopus 로고    scopus 로고
    • Effect of a selective chloride channel activator, lubiprostone, on gastrointestinal transit, gastric sensory and motor functions in healthy volunteers
    • Camilleri M, Bharucha A, Ueno R, et al. Effect of a selective chloride channel activator, lubiprostone, on gastrointestinal transit, gastric sensory and motor functions in healthy volunteers. Am J Physiol Gastrointest Liver Physiol. 2006;290(5):G942-G947.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290 , Issue.5 , pp. 942-947
    • Camilleri, M.1    Bharucha, A.2    Ueno, R.3
  • 27
    • 59449108998 scopus 로고    scopus 로고
    • Effect of a chloride channel activator, lubiprostone, on colonic sensory and motor functions in healthy subjects
    • Sweetser S, Busciglio IA, Camiller M, et al. Effect of a chloride channel activator, lubiprostone, on colonic sensory and motor functions in healthy subjects. Am J Physiol Gastrointest Liver Physiol. 2009;296(2):G295-G301.
    • (2009) Am J Physiol Gastrointest Liver Physiol , vol.296 , Issue.2 , pp. 295-301
    • Sweetser, S.1    Busciglio, I.A.2    Camiller, M.3
  • 28
    • 0036083925 scopus 로고    scopus 로고
    • Distribution of CCl-2 chloride channel in rat and human epithelial tissue
    • Lipecka J, Bali M, Thomas J, et al. Distribution of CCl-2 chloride channel in rat and human epithelial tissue. Am J Physiol Cell Physiol. 2002;282(4):C805-C816.
    • (2002) Am J Physiol Cell Physiol , vol.282 , Issue.4 , pp. 805-816
    • Lipecka, J.1    Bali, M.2    Thomas, J.3
  • 29
    • 34247163088 scopus 로고    scopus 로고
    • Expression and function of CLC and cystic fibrosis transmembrane conductance regulator chloride channels in renal epithelial tubule cells pathophysiological implications
    • Vandewalle A. Expression and function of CLC and cystic fibrosis transmembrane conductance regulator chloride channels in renal epithelial tubule cells pathophysiological implications. Chang Gung Med J. 2007;30(1):17-25.
    • (2007) Chang Gung Med J , vol.30 , Issue.1 , pp. 17-25
    • Vandewalle, A.1
  • 30
    • 6044278151 scopus 로고    scopus 로고
    • SPI-0211 activates T84 cell chloride transport and recombinant human ClC-2 chloride currents
    • Cuppoletti J, Malinowska DH, Tewari KP, et al. SPI-0211 activates T84 cell chloride transport and recombinant human ClC-2 chloride currents. Am J Physiol Cell Physiol. 2004;287(5):C1173-C1183.
    • (2004) Am J Physiol Cell Physiol , vol.287 , Issue.5 , pp. 1173-1183
    • Cuppoletti, J.1    Malinowska, D.H.2    Tewari, K.P.3
  • 31
    • 22244449305 scopus 로고    scopus 로고
    • Lubiprostone: RU 0211, SPI 0211
    • Lubiprostone: RU 0211, SPI 0211. Drugs R D. 2005;6: 245-248.
    • (2005) Drugs R D , vol.6 , pp. 245-248
  • 32
    • 0028346657 scopus 로고
    • Distinct populations of sensory neurons mediate the peristaltic reflex elicited by muscle stretch and mucosal stimulation
    • Grider JR, Jin JG. Distinct populations of sensory neurons mediate the peristaltic reflex elicited by muscle stretch and mucosal stimulation. J Neurosci. 1994;14 SUPPL 5(Pt 1):S2854-S2860.
    • (1994) J Neurosci , vol.14 , Issue.5 Pt 1 , pp. 2854-2860
    • Grider, J.R.1    Jin, J.G.2
  • 33
    • 1842583683 scopus 로고    scopus 로고
    • Basolateral ClC-2 chloride hannels in surface colon epithelium: Regulation by a direct effect of intracellular chloride
    • Catalan M, Niemeyer MI, Cid LP, et al. Basolateral ClC-2 chloride hannels in surface colon epithelium: regulation by a direct effect of intracellular chloride. Gastroenterology. 2004;126(4):1104-1114.
    • (2004) Gastroenterology , vol.126 , Issue.4 , pp. 1104-1114
    • Catalan, M.1    Niemeyer, M.I.2    Cid, L.P.3
  • 34
    • 0033637965 scopus 로고    scopus 로고
    • Expression of the chloride channel ClC-2 in the murine small intestine epithelium
    • Gyomorey K, Yeger H, Ackerly C. Expression of the chloride channel ClC-2 in the murine small intestine epithelium. Am J Physiol Cell Physiol. 2000;279(6):C1787-C1794.
    • (2000) Am J Physiol Cell Physiol , vol.279 , Issue.6 , pp. 1787-1794
    • Gyomorey, K.1    Yeger, H.2    Ackerly, C.3
  • 35
    • 0030060427 scopus 로고    scopus 로고
    • Modulation of the hyperpolarization-activated Cl- current in human T84 epithelial cells by phosphorylation
    • Fritsch J, Edelman A. Modulation of the hyperpolarization-activated Cl- current in human T84 epithelial cells by phosphorylation. J Physiol. 1996;490(Pt 1):115-128.
    • (1996) J Physiol , vol.490 , Issue.1 Pt , pp. 115-128
    • Fritsch, J.1    Edelman, A.2
  • 36
    • 52449115680 scopus 로고    scopus 로고
    • A synthetic prostone activates apical chloride channels in A6 epithelial cells
    • Bao HF, Li L, Self J, et al. A synthetic prostone activates apical chloride channels in A6 epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2009;295(2):G234-G251.
    • (2009) Am J Physiol Gastrointest Liver Physiol , vol.295 , Issue.2 , pp. 234-251
    • Bao, H.F.1    Li, L.2    Self, J.3
  • 37
  • 38
    • 67149136239 scopus 로고    scopus 로고
    • Stimulation of mucosal secretion by lubiprostone (SPI-0211) in guinea pig small intestine and colon
    • Fei G, Wang YZ, Liu S, et al. Stimulation of mucosal secretion by lubiprostone (SPI-0211) in guinea pig small intestine and colon. Am J Physiol Gastrointest Liver Physiol. 2009;296(4):G823-G832.
    • (2009) Am J Physiol Gastrointest Liver Physiol , vol.296 , Issue.4 , pp. 823-832
    • Fei, G.1    Wang, Y.Z.2    Liu, S.3
  • 39
    • 70149115877 scopus 로고    scopus 로고
    • Lupiprostone stimulates duodenal bicarbonate secretion in rats
    • Mizumori M, Akiba Y, Kaunitz JD. Lupiprostone stimulates duodenal bicarbonate secretion in rats. Dig Dis Sci. 2009;54(10):2063-2069.
    • (2009) Dig Dis Sci , vol.54 , Issue.10 , pp. 2063-2069
    • Mizumori, M.1    Akiba, Y.2    Kaunitz, J.D.3
  • 40
    • 43049156188 scopus 로고    scopus 로고
    • Activation of prostaglandin EP receptors by lubiprostone in rat and human stomach and colon
    • Bassil AK, Boman RA, Jarvie EM, et al. Activation of prostaglandin EP receptors by lubiprostone in rat and human stomach and colon. Br J Pharmacol. 2008;154(1):126-135.
    • (2008) Br J Pharmacol , vol.154 , Issue.1 , pp. 126-135
    • Bassil, A.K.1    Boman, R.A.2    Jarvie, E.M.3
  • 42
    • 38749109878 scopus 로고    scopus 로고
    • Lubiprostone, a novel type-2 chloride channel (Clc-2) activator, does not affect serum electrolyte balance in elderly and non-elderly patients with chronic idiopathic constipation
    • Rivera E, Wahle A, Joswick TR, Ueno R. Lubiprostone, a novel type-2 chloride channel (Clc-2) activator, does not affect serum electrolyte balance in elderly and non-elderly patients with chronic idiopathic constipation. Gastroenterology. 2007;132(4 SUPPL2):A191-A192.
    • (2007) Gastroenterology , vol.132 , Issue.4 SUPPL 2 , pp. 191-192
    • Rivera, E.1    Wahle, A.2    Joswick, T.R.3    Ueno, R.4
  • 43
    • 37849035566 scopus 로고    scopus 로고
    • Effect of lubiprostone, a unique agent for the treatment of chronic idiopathic constipation on clinical electrocardiogram results
    • Sprenger C, Copa A, Morganroth J, et al. Effect of lubiprostone, a unique agent for the treatment of chronic idiopathic constipation on clinical electrocardiogram results. Gastroenterology. 2007;132(4 SUPPL 2):A325.
    • (2007) Gastroenterology , vol.132 , Issue.4 SUPPL 2 , pp. 325
    • Sprenger, C.1    Copa, A.2    Morganroth, J.3
  • 44
    • 57049147616 scopus 로고    scopus 로고
    • Lubiprostone activates non-CFTR-dependent respiratory epithelial chloride secretion in cystic fibrosis Mice
    • MacDonald KD, McKenzie KR, Henderson MJ, et al. Lubiprostone activates non-CFTR-dependent respiratory epithelial chloride secretion in cystic fibrosis Mice. Am J Physiol Lung Cell Mol Physiol. 2008;295(9):L933-L940.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.295 , Issue.9 , pp. 933-940
    • Macdonald, K.D.1    McKenzie, K.R.2    Henderson, M.J.3
  • 45
    • 66149176927 scopus 로고    scopus 로고
    • Lubiprostone stimulates secretion from tracheal submucosal glands of sheep, pigs and humans
    • Joo NS, Wine JJ, Cuthbert AW. Lubiprostone stimulates secretion from tracheal submucosal glands of sheep, pigs and humans. Am J Physiol Lung Cell Mol Physiol. 2009;296(5):L811-L824.
    • (2009) Am J Physiol Lung Cell Mol Physiol , vol.296 , Issue.5 , pp. 811-824
    • Joo, N.S.1    Wine, J.J.2    Cuthbert, A.W.3
  • 46
    • 15744393922 scopus 로고    scopus 로고
    • Role of progesterone signaling in the Regulation of G-protein levels in female chronic constipation
    • Xiao ZL, Pricolo V, Biancani P, Behar J. Role of progesterone signaling in the Regulation of G-protein levels in female chronic constipation. Gastroenterology. 2005;128(3):667-675.
    • (2005) Gastroenterology , vol.128 , Issue.3 , pp. 667-675
    • Xiao, Z.L.1    Pricolo, V.2    Biancani, P.3    Behar, J.4
  • 47
    • 0025271914 scopus 로고
    • Tolerance for rectosigmoid distention in irritable bowel syndrome
    • Whitehead WE, Holtkotter B, Enck P, et al. Tolerance for rectosigmoid distention in irritable bowel syndrome. Gastroenterology. 1990;98(4):1187-1192.
    • (1990) Gastroenterology , vol.98 , Issue.4 , pp. 1187-1192
    • Whitehead, W.E.1    Holtkotter, B.2    Enck, P.3
  • 48
    • 0031032032 scopus 로고    scopus 로고
    • Repetitive sigmoid stimulation induces rectal hyperalgesia in patients with irritable bowel syndrome
    • Munakata J, Naliboff B, Harraf F, et al. Repetitive sigmoid stimulation induces rectal hyperalgesia in patients with irritable bowel syndrome. Gastroenterology. 1997;112(1):55-63.
    • (1997) Gastroenterology , vol.112 , Issue.1 , pp. 55-63
    • Munakata, J.1    Naliboff, B.2    Harraf, F.3
  • 49
    • 0032932579 scopus 로고    scopus 로고
    • Abdominal symptoms are not related to anorectal function in the irritable bowel syndrome
    • Ragnarrsson G, Hallbook O, Bodemar G. Abdominal symptoms are not related to anorectal function in the irritable bowel syndrome. Scand J Gastroenterol. 1999;34(3):250-258.
    • (1999) Scand J Gastroenterol , vol.34 , Issue.3 , pp. 250-258
    • Ragnarrsson, G.1    Hallbook, O.2    Bodemar, G.3
  • 50
    • 33745856201 scopus 로고    scopus 로고
    • Effect of sex on perception of rectosigmoid stimuli in irritable bowel syndrome
    • Chang L, Mayer EA, Labus J, et al. Effect of sex on perception of rectosigmoid stimuli in irritable bowel syndrome. Am J Physiol Regul Integr Comp Physiol. 2006;29(2):R277-R284.
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.29 , Issue.2 , pp. 277-284
    • Chang, L.1    Mayer, E.A.2    Labus, J.3
  • 51
    • 0036282244 scopus 로고    scopus 로고
    • The menstrual cycle affects rectal sensitivity in patients with irritable bowel syndrome but not healthy volunteers
    • Houghton LA, Lea R, Jackson N, Whorwell PU. The menstrual cycle affects rectal sensitivity in patients with irritable bowel syndrome but not healthy volunteers. Gut. 2002;50(4):471-474.
    • (2002) Gut , vol.50 , Issue.4 , pp. 471-474
    • Houghton, L.A.1    Lea, R.2    Jackson, N.3    Whorwell, P.U.4
  • 52
    • 0034210451 scopus 로고    scopus 로고
    • Gender differences in regional brain response to visceral pressure in IBS patients
    • Berman S, Munakata J, Naliboff BD, et al. Gender differences in regional brain response to visceral pressure in IBS patients. Eur J Pain. 2000;4(2):157-172.
    • (2000) Eur J Pain , vol.4 , Issue.2 , pp. 157-172
    • Berman, S.1    Munakata, J.2    Naliboff, B.D.3
  • 53
    • 0038724271 scopus 로고    scopus 로고
    • Sex-related differences in IBS patients Central processing of visceral stimuli
    • Naliboff BD, Berman S, Chang L, et al. Sex-related differences in IBS patients:central processing of visceral stimuli. Gastroenterology. 2003;124(7):1738-1747.
    • (2003) Gastroenterology , vol.124 , Issue.7 , pp. 1738-1747
    • Naliboff, B.D.1    Berman, S.2    Chang, L.3
  • 54
    • 0032848856 scopus 로고    scopus 로고
    • Improvement in pain and bowel function in female irritable bowel patients with alosetron, a 5-HT3 receptor antagonist
    • Camilleri, M, Mayer EA, Drossman DA, et al. Improvement in pain and bowel function in female irritable bowel patients with alosetron, a 5-HT3 receptor antagonist. Aliment Pharmacol Ther. 1999;13(9): 1149-1159.
    • (1999) Aliment Pharmacol Ther , vol.13 , Issue.9 , pp. 1149-1159
    • Camilleri, M.1    Mayer, E.A.2    Drossman, D.A.3
  • 55
    • 13744263696 scopus 로고    scopus 로고
    • A dose-ranging, phase II study of the efficacy and safety of alosetron hydrochloride (Lotronex) in men with diarrhea-predominant IBS
    • Chang L, Ameen VZ, Dukes GE, McSorley D, Mayer EA. A dose-ranging, phase II study of the efficacy and safety of alosetron hydrochloride (Lotronex) in men with diarrhea-predominant IBS. Am J Gastroenterol. 2005;100(1):115-123.
    • (2005) Am J Gastroenterol , vol.100 , Issue.1 , pp. 115-123
    • Chang, L.1    Ameen, V.Z.2    Dukes, G.E.3    McSorley, D.4    Mayer, E.A.5
  • 56
    • 4644348092 scopus 로고    scopus 로고
    • Cilansetron in irritable bowel syndrome with diarrhea predominance (IBS-D)Efficacy and safety in a 6 month study
    • Bradette M, Moennikes H, Carter F, et al. Cilansetron in irritable bowel syndrome with diarrhea predominance (IBS-D). Efficacy and safety in a 6 month study. Gastroenterology. 2004; 126(4 SUPPL 2):A42.
    • (2004) Gastroenterology , vol.126 , Issue.4 SUPPL 2 , pp. 42
    • Bradette, M.1    Moennikes, H.2    Carter, F.3
  • 57
    • 11144345503 scopus 로고    scopus 로고
    • Cilansetron, a novel 5-HT3 antagonist, demonstrated efficacy in males with irritable bowel syndrome with diarrhea predominance (IBS-D)
    • Coremnans G, Clouse RE, Carter F, Krause, G, Caras S, Steinborm C. Cilansetron, a novel 5-HT3 antagonist, demonstrated efficacy in males with irritable bowel syndrome with diarrhea predominance (IBS-D). Gastroenterology. 2004;126(4 SUPPL 2):A643.
    • (2004) Gastroenterology , vol.126 , Issue.4 SUPPL 2 , pp. 643
    • Coremnans, G.1    Clouse, R.E.2    Carter, F.3    Krause, G.4    Caras, S.5    Steinborm, C.6
  • 58
    • 0034794595 scopus 로고    scopus 로고
    • Tegaserod, a 5HT (4) receptor partial agonist, relieves symptoms in irritable bowel syndrome patients with abdominal pain, bloating and constipation
    • Muller-Lissner SA, Fumagalli I, Bardhan KD, et al. Tegaserod, a 5HT (4) receptor partial agonist, relieves symptoms in irritable bowel syndrome patients with abdominal pain, bloating and constipation. Aliment Pharmacol Ther. 2001;15(10):1655-1666.
    • (2001) Aliment Pharmacol Ther , vol.15 , Issue.10 , pp. 1655-1666
    • Muller-Lissner, S.A.1    Fumagalli, I.2    Bardhan, K.D.3
  • 59
    • 0037799916 scopus 로고    scopus 로고
    • An Asia-Pacific, double-blind, placebo controlled randomized study to evaluate the efficacy, safety and tolerability of tegaserod in patients with irritable bowel syndrome
    • Kellow J, Lee OY, Chang FY, et al. An Asia-Pacific, double-blind, placebo controlled randomized study to evaluate the efficacy, safety and tolerability of tegaserod in patients with irritable bowel syndrome. Gut. 2003;52(5):671-676.
    • (2003) Gut , vol.52 , Issue.5 , pp. 671-676
    • Kellow, J.1    Lee, O.Y.2    Chang, F.Y.3
  • 60
    • 0036325415 scopus 로고    scopus 로고
    • Serotonin-transporter polymorphism pharmacogenetics in diarrhea-predominant irritable bowel syndrome
    • Camilleri M, Atanasova E, Carlson PJ, et al. Serotonin-transporter polymorphism pharmacogenetics in diarrhea-predominant irritable bowel syndrome. Gastroenterology. 2002;123(2):425-432.
    • (2002) Gastroenterology , vol.123 , Issue.2 , pp. 425-432
    • Camilleri, M.1    Atanasova, E.2    Carlson, P.J.3
  • 61
    • 0037741690 scopus 로고    scopus 로고
    • Efficacy and safety of a novel compound, RU-0211, for the treatment of constipation
    • Johanson JF, Gargano MA, Patchen ML, Ueno R. Efficacy and safety of a novel compound, RU-0211, for the treatment of constipation. Gastroenterology. 2002;122(1 SUPPL 4):A315.
    • (2002) Gastroenterology , vol.122 , Issue.1 SUPPL 4 , pp. 315
    • Johanson, J.F.1    Gargano, M.A.2    Patchen, M.L.3    Ueno, R.4
  • 62
    • 2442466372 scopus 로고    scopus 로고
    • Efficacy and safety of RU-0211, a novel chloride channel activator, for the treatment of constipation
    • Johanson JF, Gargano MA, Patchen ML, Ueno R. Phase III efficacy and safety of RU-0211, a novel chloride channel activator, for the treatment of constipation. Gastroenterology. 2003;124(4 SUPPL 1):A48.
    • (2003) Gastroenterology , vol.124 , Issue.4 SUPPL 1 , pp. 48
    • Johanson, J.F.1    Gargano, M.A.2    Patchen, M.L.3    Ueno, R.4    Phase, I.I.I.5
  • 63
    • 33645058986 scopus 로고    scopus 로고
    • Study of lubiprostone, a chloride channel-2 (CIC-2) activator for treatment of constipation: Safety and primary efficacy
    • Johanson JF, Gargano MA, Patchen ML, Ueno R. Phase III study of lubiprostone, a chloride channel-2 (CIC-2) activator for treatment of constipation: Safety and primary efficacy. Am J Gastroenterol. 2005; 100(9 SUPPL 9s):S328.
    • (2005) Am J Gastroenterol , vol.100 , Issue.9 SUPPL 9s , pp. 328
    • Johanson, J.F.1    Gargano, M.A.2    Patchen, M.L.3    Ueno, R.4    Phase, I.I.I.5
  • 64
    • 34248595894 scopus 로고    scopus 로고
    • Lubiprostone, a locally acting chloride channelc activator, in adult patients with chronic constipation: A double-blind, placebo-controlled, dose-ranging study to evaluate efficacy and safety
    • Johanson JF, Ueno R. Lubiprostone, a locally acting chloride channelc activator, in adult patients with chronic constipation: a double-blind, placebo-controlled, dose-ranging study to evaluate efficacy and safety. Aliment Pharmacol Ther. 2007;25(11):1351-1361.
    • (2007) Aliment Pharmacol Ther , vol.25 , Issue.11 , pp. 1351-1361
    • Johanson, J.F.1    Ueno, R.2
  • 65
    • 77950347294 scopus 로고    scopus 로고
    • Eff icacy and safety of lubiprostone in chronic constipation
    • Barish CF, Drossman D, Johanson JF, Ueno R. Eff icacy and safety of lubiprostone in chronic constipation. Dig Dis Sci. 2010;55(4):1090-1097.
    • (2010) Dig Dis Sci , vol.55 , Issue.4 , pp. 1090-1097
    • Barish, C.F.1    Drossman, D.2    Johanson, J.F.3    Ueno, R.4
  • 66
    • 37849024665 scopus 로고    scopus 로고
    • Multi-center, 4-week, double-blind, randomized, placebo-controlled trial of lubiprostone, a locally-acting type-2 chloride channel activator in patients with chronic constipation
    • Johanson JF, Morton D, Geenen J, Ueno R. Multi-center, 4-week, double-blind, randomized, placebo-controlled trial of lubiprostone, a locally-acting type-2 chloride channel activator in patients with chronic constipation. Am J Gastroenterol. 2008;103(1):170-177.
    • (2008) Am J Gastroenterol , vol.103 , Issue.1 , pp. 170-177
    • Johanson, J.F.1    Morton, D.2    Geenen, J.3    Ueno, R.4
  • 68
    • 33745798874 scopus 로고    scopus 로고
    • Lubiprostone (amitiza) for chronic constipation
    • Anonymous
    • Anonymous. Lubiprostone (amitiza) for chronic constipation. Med Lett Drugs Ther. 2006;48(1236):47-48.
    • (2006) Med Lett Drugs Ther , vol.48 , Issue.1236 , pp. 47-48
  • 69
    • 2442466372 scopus 로고    scopus 로고
    • Efficacy and safety of RU-0211, a novel chloride channel activator, for the treatment of constipation
    • Johanson JF, Gargano MA, Holland PC, Patchen ML, Ueno R. Phase III efficacy and safety of RU-0211, a novel chloride channel activator, for the treatment of constipation. Gastroenterology. 2003; 124(4 SUPPL 1):A104.
    • (2003) Gastroenterology , vol.124 , Issue.4 SUPPL 1 , pp. 104
    • Johanson, J.F.1    Gargano, M.A.2    Holland, P.C.3    Patchen, M.L.4    Ueno, R.5    Phase, I.I.I.6
  • 70
    • 33750012942 scopus 로고    scopus 로고
    • Long-term safety and efficacy of lubiprostone for the treatment of chronic constipation in elderly subjects
    • Ueno R, Panas R, Wahle A, Zhu Y, Holland PC. Long-term safety and efficacy of lubiprostone for the treatment of chronic constipation in elderly subjects. Gastroenterology. 2006; 130(4 SUPPL 2):A188.
    • (2006) Gastroenterology , vol.130 , Issue.4 SUPPL 2 , pp. 188
    • Ueno, R.1    Panas, R.2    Wahle, A.3    Zhu, Y.4    Holland, P.C.5
  • 71
    • 33645375828 scopus 로고    scopus 로고
    • Multi-center open label study of lubiprostone for the treatment of chronic constipation
    • Johanson JF, Gargano MA, Patchen ML, Ueno R. Multi-center open label study of lubiprostone for the treatment of chronic constipation. Am J Gastroenterol. 2005;100(9 SUPPL 9):S331.
    • (2005) Am J Gastroenterol , vol.100 , Issue.9 SUPPL 9 , pp. 331
    • Johanson, J.F.1    Gargano, M.A.2    Patchen, M.L.3    Ueno, R.4
  • 72
    • 18144425423 scopus 로고    scopus 로고
    • Randomized withdrawal study of RU-0211, a novel chloride channel activator for the treatment of constipation
    • Johanson JF, Gargano MA, Patchen ML, Ueno R. Phase III, randomized withdrawal study of RU-0211, a novel chloride channel activator for the treatment of constipation. Gastroenterology. 2004; 126(4 SUPPL 2):S100
    • (2004) Gastroenterology , vol.126 , Issue.4 SUPPL 2 , pp. 100
    • Johanson, J.F.1    Gargano, M.A.2    Patchen, M.L.3    Ueno, R.4    Phase, I.I.I.5
  • 73
    • 55649095470 scopus 로고    scopus 로고
    • Discontinuation of lubiprostone treatment for irritable bowel syndrome with constipation is not associated with symptom increase or recurrence: Results from a randomized withdrawal study
    • Chey WD, Saad RJ, Panas R, Wahle A, Ueno R. Discontinuation of lubiprostone treatment for irritable bowel syndrome with constipation is not associated with symptom increase or recurrence: results from a randomized withdrawal study. Gastroenterology. 2008; 134(4 SUPPL 1):A401.
    • (2008) Gastroenterology , vol.134 , Issue.4 SUPPL 1 , pp. 401
    • Chey, W.D.1    Saad, R.J.2    Panas, R.3    Wahle, A.4    Ueno, R.5
  • 74
    • 58149103805 scopus 로고    scopus 로고
    • Clinical trial: Lubiprostone in patients with constipation-associated irritable bowel syndrome - results of two randomized, placebo-controlled studies
    • Drossman DA, Chey WD, Johanson JF, et al. Clinical trial: lubiprostone in patients with constipation-associated irritable bowel syndrome - results of two randomized, placebo-controlled studies. Aliment Pharmacol Ther. 2009;29(3):329-341.
    • (2009) Aliment Pharmacol Ther , vol.29 , Issue.3 , pp. 329-341
    • Drossman, D.A.1    Chey, W.D.2    Johanson, J.F.3
  • 75
    • 55649119956 scopus 로고    scopus 로고
    • Health-related quality of life in adults with irritable bowel syndrome with constipation: Results of combined analysis of two phase 3 studies with lubiprostone
    • Drossman DA, Chey WD, Scott C, Panas R, Ueno R. Health-related quality of life in adults with irritable bowel syndrome with constipation: results of combined analysis of two phase 3 studies with lubiprostone. Gastroenterology. 2008;134(4 SUPPL 1):A469.
    • (2008) Gastroenterology , vol.134 , Issue.4 SUPPL 1 , pp. 469
    • Drossman, D.A.1    Chey, W.D.2    Scott, C.3    Panas, R.4    Ueno, R.5
  • 76
    • 46749084558 scopus 로고    scopus 로고
    • What symptoms drive global symptom improvement with lubiprostone in patients with irritable bowel syndrome and constipation: Data from two multicenter, randomized, placebo-controlled trials
    • Chey WD, Drossman DA, Scott C, Panas R, Ueno R. What symptoms drive global symptom improvement with lubiprostone in patients with irritable bowel syndrome and constipation: data from two multicenter, randomized, placebo-controlled trials. Gastroenterology. 2008;134(4 SUPPL 1):A28.
    • (2008) Gastroenterology , vol.134 , Issue.4 SUPPL 1 , pp. 28
    • Chey, W.D.1    Drossman, D.A.2    Scott, C.3    Panas, R.4    Ueno, R.5
  • 78
    • 33744830627 scopus 로고    scopus 로고
    • Abnormal intestinal permeability in subgroups of diarrhea-predominant irritable bowel syndrome
    • Dunlop SP, Hepben J, Campbell E, et al. Abnormal intestinal permeability in subgroups of diarrhea-predominant irritable bowel syndrome. Am J Gastroenterol. 2006;101(6):1288-1204.
    • (2006) Am J Gastroenterol , vol.101 , Issue.6 , pp. 1288-1204
    • Dunlop, S.P.1    Hepben, J.2    Campbell, E.3
  • 79
    • 11144330063 scopus 로고    scopus 로고
    • Intestinal permeability in patients with irritable bowel syndrome after a waterborne outbreak of acute gastroenteritis in Walkerton, Ontario
    • Marshall JK, Thabane M, Garg AX, Clark W, Medings J, Collins SM. Intestinal permeability in patients with irritable bowel syndrome after a waterborne outbreak of acute gastroenteritis in Walkerton, Ontario. Aliment Pharmacol Ther. 2004;20(11-12):1317-1322.
    • (2004) Aliment Pharmacol Ther , vol.20 , Issue.11-12 , pp. 1317-1322
    • Marshall, J.K.1    Thabane, M.2    Garg, A.X.3    Clark, W.4    Medings, J.5    Collins, S.M.6
  • 80
    • 0033665517 scopus 로고    scopus 로고
    • Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute Campylobacter enteritis and in post-dysenteric irritable bowel syndrome
    • Spiller RC, Jenkins D, Thornley JP, et al. Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute Campylobacter enteritis and in post-dysenteric irritable bowel syndrome. Gut. 2000;47(5):804-811.
    • (2000) Gut , vol.47 , Issue.5 , pp. 804-811
    • Spiller, R.C.1    Jenkins, D.2    Thornley, J.P.3
  • 82
    • 71549121350 scopus 로고    scopus 로고
    • Review article: New receptor targets for medical therapy in irritable bowel syndrome
    • Camilleri M. Review article: new receptor targets for medical therapy in irritable bowel syndrome. Aliment Pharmacol Ther. 2010;31(1):35-46.
    • (2010) Aliment Pharmacol Ther , vol.31 , Issue.1 , pp. 35-46
    • Camilleri, M.1
  • 83
    • 70350570781 scopus 로고    scopus 로고
    • A double-blind, placebo controlled trial to evaluate the safety and tolerability of prucalo-pride oral solution in constipated elderly patients living in a nursing facility
    • Camilleri M, Kerstens R, Beyens G, Robinson P, Vandeplassche L. A double-blind, placebo controlled trial to evaluate the safety and tolerability of prucalo-pride oral solution in constipated elderly patients living in a nursing facility. Gastroenterology. 2009; 136 SUPPL 1:S240.
    • (2009) Gastroenterology , vol.136 , Issue.1 , pp. 240
    • Camilleri, M.1    Kerstens, R.2    Beyens, G.3    Robinson, P.4    Vandeplassche, L.5
  • 84
    • 71549124553 scopus 로고    scopus 로고
    • Long-term follow up of safety and satisfaction with bowel function in response to oral prucalopride in patients with chronic constipation
    • Camilleri M, Beyens G, Kertsens R, Vandeplassche L. Long-term follow up of safety and satisfaction with bowel function in response to oral prucalopride in patients with chronic constipation. Gastroenterology. 2009;136 SUPPL 1:S160.
    • (2009) Gastroenterology , vol.136 , Issue.1 , pp. 160
    • Camilleri, M.1    Beyens, G.2    Kertsens, R.3    Vandeplassche, L.4
  • 85
    • 7044269199 scopus 로고    scopus 로고
    • Uroguanylin and guanylin peptides: Pharmacology and experimental and therapeutics
    • Forte LR Jr. Uroguanylin and guanylin peptides: pharmacology and experimental and therapeutics. Pharmacol Ther. 2004;104(2):137-162.
    • (2004) Pharmacol Ther , vol.104 , Issue.2 , pp. 137-162
    • Forte Jr., L.R.1
  • 86
    • 77249122338 scopus 로고    scopus 로고
    • Efficacy of linaclotide for patients with chronic constipation
    • Lembo AJ, Kurtz CB, Macdougall JE, et al. Efficacy of linaclotide for patients with chronic constipation. Gastroenterology. 2010;138(3):886-895.
    • (2010) Gastroenterology , vol.138 , Issue.3 , pp. 886-895
    • Lembo, A.J.1    Kurtz, C.B.2    Macdougall, J.E.3
  • 87
    • 67349084855 scopus 로고    scopus 로고
    • International survey of patients with IBS: Symptom features and their severity, health status treatments, and risk taking to achieve clinical benefit
    • Drossman DA, Morris CB, Schneck S, et al. International survey of patients with IBS: symptom features and their severity, health status treatments, and risk taking to achieve clinical benefit. J Clin Gastroenterol. 2009;43(6):541-550.
    • (2009) J Clin Gastroenterol , vol.43 , Issue.6 , pp. 541-550
    • Drossman, D.A.1    Morris, C.B.2    Schneck, S.3
  • 88
    • 0026636839 scopus 로고
    • The irritable bowel syndrome: Review and a graduated multicomponent treatment approach
    • Drossman DA, Thompson WG. The irritable bowel syndrome: review and a graduated multicomponent treatment approach. Ann Intern Med. 1992;116(12 Pt 1):1009-1016.
    • (1992) Ann Intern Med , vol.116 , Issue.12 Pt 1 , pp. 1009-1016
    • Drossman, D.A.1    Thompson, W.G.2
  • 89
    • 68349141680 scopus 로고    scopus 로고
    • Developing valid and reliable health utilities in irritable bowel syndrome: Results from the IBS PROOF cohort
    • Spiegel B, Harris LA, Lucak S, et al. Developing valid and reliable health utilities in irritable bowel syndrome: results from the IBS PROOF cohort. Am J Gastroenterol. 2009;104(8):1984-1991.
    • (2009) Am J Gastroenterol , vol.104 , Issue.8 , pp. 1984-1991
    • Spiegel, B.1    Harris, L.A.2    Lucak, S.3
  • 90
    • 53149118575 scopus 로고    scopus 로고
    • Predictors of patient-assessed illness severity in irritable bowel syndrome
    • Spiegel B, Strickland A, Naliboff BD, Mayer EA, Chang L. Predictors of patient-assessed illness severity in irritable bowel syndrome. Am J Gastroenterol. 2008;103(10):2536-2543.
    • (2008) Am J Gastroenterol , vol.103 , Issue.10 , pp. 2536-2543
    • Spiegel, B.1    Strickland, A.2    Naliboff, B.D.3    Mayer, E.A.4    Chang, L.5


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