Lubiprostone activates non-CFTR-dependent respiratory epithelial chloride secretion in cystic fibrosis mice

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 295, Issue 5, 2008, Pages

  MacDonald, Kelvin D ^a   McKenzie, Karen R ^a   Henderson, Mark J ^a   Hawkins, Charles E ^a   Vij, Neeraj ^a   Zeitlin, Pamela L ^a,b  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b NONE   (United States)

Author keywords

Murine; Nasal potential difference; Prostone

Indexed keywords

AMILORIDE; CALCIUM CHANNEL; CHLORIDE CHANNEL; CHLORIDE CHANNEL 2; LUBIPROSTONE; RINGER SOLUTION; TRANSMEMBRANE CONDUCTANCE REGULATOR; UNCLASSIFIED DRUG;

ANIMAL MODEL; ARTICLE; CELL MEMBRANE; CHLORIDE TRANSPORT; CONTROLLED STUDY; FEMALE; LUNG FIBROSIS; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; RESPIRATORY EPITHELIUM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SODIUM ABSORPTION;

ADENOSINE TRIPHOSPHATE; ADMINISTRATION, TOPICAL; ALPROSTADIL; ANIMALS; BIOLOGICAL TRANSPORT; CHLORIDE CHANNELS; CHLORIDES; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC CONDUCTIVITY; EPITHELIUM; GENE EXPRESSION REGULATION; MEMBRANE POTENTIALS; MICE; MICE, KNOCKOUT; RESPIRATORY SYSTEM; RNA, MESSENGER; SUBCELLULAR FRACTIONS;

EID: 57049147616     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.90221.2008     Document Type: Article

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