메뉴 건너뛰기




Volumn 107, Issue 50, 2010, Pages 21382-21387

UNC-45/CRO1/She4p (UCS) protein forms elongated dimer and joins two myosin heads near their actin binding region

Author keywords

Chaperone; Myosin stability; Processivity

Indexed keywords

ACTIN; ADENOSINE TRIPHOSPHATE; CRO1 PROTEIN; EPITOPE; FUNGAL PROTEIN; MYOSIN; SHE4P PROTEIN; UNC 45 PROTEIN; UNCLASSIFIED DRUG;

EID: 78650730499     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1013038107     Document Type: Article
Times cited : (42)

References (27)
  • 1
    • 75149128079 scopus 로고    scopus 로고
    • Myosin VI: An innovative motor that challenged the swinging lever arm hypothesis
    • Spudich JA, Sivaramakrishnan S (2010) Myosin VI: An innovative motor that challenged the swinging lever arm hypothesis. Nat Rev Mol Cell Biol 11:128-137.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 128-137
    • Spudich, J.A.1    Sivaramakrishnan, S.2
  • 2
    • 0029913456 scopus 로고    scopus 로고
    • The neck region of the myosin motor domain acts as a lever arm to generate movement
    • Uyeda TQ, Abramson PD, Spudich JA (1996) The neck region of the myosin motor domain acts as a lever arm to generate movement. Proc Natl Acad Sci USA 93:4459-4464.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 4459-4464
    • Uyeda, T.Q.1    Abramson, P.D.2    Spudich, J.A.3
  • 3
    • 0028558668 scopus 로고
    • Role of myosin light chains
    • Trybus KM (1994) Role of myosin light chains. J Muscle Res Cell Motil 15:587-594.
    • (1994) J Muscle Res Cell Motil , vol.15 , pp. 587-594
    • Trybus, K.M.1
  • 4
    • 0034618049 scopus 로고    scopus 로고
    • Two distinct regions in a yeast myosin-V tail domain are required for the movement of different cargoes
    • Catlett NL, Duex JE, Tang F, Weisman LS (2000) Two distinct regions in a yeast myosin-V tail domain are required for the movement of different cargoes. J Cell Biol 150:513-526.
    • (2000) J Cell Biol , vol.150 , pp. 513-526
    • Catlett, N.L.1    Duex, J.E.2    Tang, F.3    Weisman, L.S.4
  • 5
    • 34547126025 scopus 로고    scopus 로고
    • Identification of a minimal myosinVa binding site within an intrinsically unstructured domain of melanophilin
    • Geething NC, Spudich JA (2007) Identification of a minimal myosinVa binding site within an intrinsically unstructured domain of melanophilin. J Biol Chem 282:21518-21528.
    • (2007) J Biol Chem , vol.282 , pp. 21518-21528
    • Geething, N.C.1    Spudich, J.A.2
  • 8
    • 0030875775 scopus 로고    scopus 로고
    • Mating type switching in yeast controlled by asymmetric localization of ASH1 mRNA
    • Long RM, et al. (1997) Mating type switching in yeast controlled by asymmetric localization of ASH1 mRNA. Science 277:383-387.
    • (1997) Science , vol.277 , pp. 383-387
    • Long, R.M.1
  • 9
    • 0030930836 scopus 로고    scopus 로고
    • Actin-dependent localization of an RNA encoding a cell-fate determinant in yeast
    • Takizawa PA, Sil A, Swedlow JR, Herskowitz I, Vale RD (1997) Actin-dependent localization of an RNA encoding a cell-fate determinant in yeast. Nature 389:90-93.
    • (1997) Nature , vol.389 , pp. 90-93
    • Takizawa, P.A.1    Sil, A.2    Swedlow, J.R.3    Herskowitz, I.4    Vale, R.D.5
  • 10
    • 0037847544 scopus 로고    scopus 로고
    • The UCS domain protein She4p binds to myosin motor domains and is essential for class i and class v myosin function
    • Wesche S, Arnold M, Jansen RP (2003) The UCS domain protein She4p binds to myosin motor domains and is essential for class I and class V myosin function. Curr Biol 13:715-724.
    • (2003) Curr Biol , vol.13 , pp. 715-724
    • Wesche, S.1    Arnold, M.2    Jansen, R.P.3
  • 11
    • 0038128252 scopus 로고    scopus 로고
    • She4p/Dim1p interacts with the motor domain of unconventional myosins in the budding yeast, Saccharomyces cerevisiae
    • Toi H, et al. (2003) She4p/Dim1p interacts with the motor domain of unconventional myosins in the budding yeast, Saccharomyces cerevisiae. Mol Biol Cell 14:2237-2249.
    • (2003) Mol Biol Cell , vol.14 , pp. 2237-2249
    • Toi, H.1
  • 12
    • 0037169028 scopus 로고    scopus 로고
    • Role of the myosin assembly protein UNC-45 as a molecular chaperone for myosin
    • Barral JM, Hutagalung AH, Brinker A, Hartl FU, Epstein HF (2002) Role of the myosin assembly protein UNC-45 as a molecular chaperone for myosin. Science 295:669-671.
    • (2002) Science , vol.295 , pp. 669-671
    • Barral, J.M.1    Hutagalung, A.H.2    Brinker, A.3    Hartl, F.U.4    Epstein, H.F.5
  • 13
    • 47749122973 scopus 로고    scopus 로고
    • Unc45b forms a cytosolic complex with Hsp90 and targets the unfolded myosin motor domain
    • Srikakulam R, Liu L, Winkelmann DA (2008) Unc45b forms a cytosolic complex with Hsp90 and targets the unfolded myosin motor domain. PLoS One 3:e2137.
    • (2008) PLoS One , vol.3
    • Srikakulam, R.1    Liu, L.2    Winkelmann, D.A.3
  • 14
    • 59649104608 scopus 로고    scopus 로고
    • Rng3, a member of the UCS family of myosin co-chaperones, associates with myosin heavy chains cotranslationally
    • Amorim MJ, Mata J (2008) Rng3, a member of the UCS family of myosin co-chaperones, associates with myosin heavy chains cotranslationally. EMBO Rep 10:186-191.
    • (2008) EMBO Rep , vol.10 , pp. 186-191
    • Amorim, M.J.1    Mata, J.2
  • 15
    • 33847392824 scopus 로고    scopus 로고
    • The myosin co-chaperone UNC-45 is required for skeletal and cardiac muscle function in zebrafish
    • Wohlgemuth SL, Crawford BD, Pilgrim DB (2007) The myosin co-chaperone UNC-45 is required for skeletal and cardiac muscle function in zebrafish. Dev Biol 303:483-492.
    • (2007) Dev Biol , vol.303 , pp. 483-492
    • Wohlgemuth, S.L.1    Crawford, B.D.2    Pilgrim, D.B.3
  • 16
    • 34547103542 scopus 로고    scopus 로고
    • The UCS factor Steif/Unc-45b interacts with the heat shock protein Hsp90a during myofibrillogenesis
    • Etard C, et al. (2007) The UCS factor Steif/Unc-45b interacts with the heat shock protein Hsp90a during myofibrillogenesis. Dev Biol 308:133-143.
    • (2007) Dev Biol , vol.308 , pp. 133-143
    • Etard, C.1
  • 17
    • 15244348370 scopus 로고    scopus 로고
    • Hsp90 protein in fission yeast Swo1p and UCS protein Rng3p facilitate myosin II assembly and function
    • Mishra M, D'Souza VM, Chang KC, Huang Y, Balasubramanian MK (2005) Hsp90 protein in fission yeast Swo1p and UCS protein Rng3p facilitate myosin II assembly and function. Eukaryot Cell 4:567-576.
    • (2005) Eukaryot Cell , vol.4 , pp. 567-576
    • Mishra, M.1    D'Souza, V.M.2    Chang, K.C.3    Huang, Y.4    Balasubramanian, M.K.5
  • 18
    • 77952744235 scopus 로고    scopus 로고
    • Drosophila UNC-45 prevents heat-induced aggregation of skeletal muscle myosin and facilitates refolding of citrate synthase
    • Melkani GC, Lee CF, Cammarato A, Bernstein SI (2010) Drosophila UNC-45 prevents heat-induced aggregation of skeletal muscle myosin and facilitates refolding of citrate synthase. Biochem Biophys Res Commun 396:317-322.
    • (2010) Biochem Biophys Res Commun , vol.396 , pp. 317-322
    • Melkani, G.C.1    Lee, C.F.2    Cammarato, A.3    Bernstein, S.I.4
  • 19
    • 77957801950 scopus 로고    scopus 로고
    • Knockdown and overexpression of Unc-45b result in defective myofibril organization in skeletal muscles of zebrafish embryos
    • Bernick E, Zhang P, Du S (2010) Knockdown and overexpression of Unc-45b result in defective myofibril organization in skeletal muscles of zebrafish embryos. BMC Cell Biol 11:70-82.
    • (2010) BMC Cell Biol , vol.11 , pp. 70-82
    • Bernick, E.1    Zhang, P.2    Du, S.3
  • 20
    • 4043096960 scopus 로고    scopus 로고
    • Regulation of the myosin-directed chaperone UNC-45 by a novel E3/E4-multiubiquitylation complex in C. elegans
    • Hoppe T, et al. (2004) Regulation of the myosin-directed chaperone UNC-45 by a novel E3/E4-multiubiquitylation complex in C. elegans. Cell 118:337-349.
    • (2004) Cell , vol.118 , pp. 337-349
    • Hoppe, T.1
  • 21
    • 45249089995 scopus 로고    scopus 로고
    • Yeast UCS proteins promote actomyosin interactions and limit myosin turnover in cells
    • LordM, Sladewski TE, Pollard TD (2008) Yeast UCS proteins promote actomyosin interactions and limit myosin turnover in cells. Proc Natl Acad Sci USA 105:8014-8019.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 8014-8019
    • Lordm Sladewski, T.E.1    Pollard, T.D.2
  • 22
    • 7244226219 scopus 로고    scopus 로고
    • UCS protein Rng3p activates actin filament gliding by fission yeast myosin-II
    • LordM, Pollard TD (2004) UCS protein Rng3p activates actin filament gliding by fission yeast myosin-II. J Cell Biol 167:315-325.
    • (2004) J Cell Biol , vol.167 , pp. 315-325
    • Lord, M.1    Pollard, T.D.2
  • 23
    • 0032583155 scopus 로고    scopus 로고
    • Unc-45 mutations in Caenorhabditis elegans implicate a CRO1/She4p-like domain in myosin assembly
    • Barral JM, Bauer CC, Ortiz I, Epstein HF (1998) Unc-45 mutations in Caenorhabditis elegans implicate a CRO1/She4p-like domain in myosin assembly. J Cell Biol 143:1215-1225.
    • (1998) J Cell Biol , vol.143 , pp. 1215-1225
    • Barral, J.M.1    Bauer, C.C.2    Ortiz, I.3    Epstein, H.F.4
  • 24
    • 32944481073 scopus 로고    scopus 로고
    • Mutation of surface residues to promote crystallization of activated factor XI as a complex with benzamidine: An essential step for the iterative structurebased design of factor XI inhibitors
    • Jin L, et al. (2005) Mutation of surface residues to promote crystallization of activated factor XI as a complex with benzamidine: An essential step for the iterative structurebased design of factor XI inhibitors. Acta Crystallogr, Sect D: Biol Crystallogr 61:1418-1425.
    • (2005) Acta Crystallogr, Sect D: Biol Crystallogr , vol.61 , pp. 1418-1425
    • Jin, L.1
  • 25
    • 0033766762 scopus 로고    scopus 로고
    • A myosin family tree
    • Hodge T, Cope MJ (2000) A myosin family tree. J Cell Sci 113:3353-3354.
    • (2000) J Cell Sci , vol.113 , pp. 3353-3354
    • Hodge, T.1    Cope, M.J.2
  • 26
    • 0035312384 scopus 로고    scopus 로고
    • Myosin motors: Missing structures and hidden springs
    • Houdusse A, Sweeney HL (2001) Myosin motors: Missing structures and hidden springs. Curr Opin Struct Biol 11:182-194.
    • (2001) Curr Opin Struct Biol , vol.11 , pp. 182-194
    • Houdusse, A.1    Sweeney, H.L.2
  • 27
    • 10644225267 scopus 로고    scopus 로고
    • Three myosin v structures delineate essential features of chemo-mechanical transduction
    • Coureux PD, Sweeney HL, Houdusse A (2004) Three myosin V structures delineate essential features of chemo-mechanical transduction. EMBO J 23:4527-4537.
    • (2004) EMBO J , vol.23 , pp. 4527-4537
    • Coureux, P.D.1    Sweeney, H.L.2    Houdusse, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.