Substance P in the cerebrospinal fluid-contacting nucleus contributes to morphine physical dependence in rats

Neuroscience Letters

Volumn 488, Issue 2, 2011, Pages 188-192

  Lu, Xian Fu ^a,b   Li, Yuan Yuan ^b,c   Wang, Chun Guang ^b   Wei, Jin Qiu ^b   Ye, Ying ^a,b   Zhang, Li Cai ^a,b   Cao, Jun Li ^b  

^a CHINA MEDICAL UNIVERSITY   (China)

^b XUZHOU MEDICAL UNIVERSITY   (China)

^c SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

Author keywords

Immunofluorescence; Morphine dependence and withdrawal; Substance P; The cerebrospinal fluid contacting nucleus; The distal cerebrospinal fluid contacting neurons

Indexed keywords

MORPHINE; SUBSTANCE P [2 DEXTRO PROLINE 7 DEXTRO PHENYLALANINE 9 DEXTRO TRYPTOPHAN]; SUBSTANCE P DERIVATIVE; UNCLASSIFIED DRUG;

ALLODYNIA; ANIMAL EXPERIMENT; ARTICLE; BRAIN NUCLEUS; CEREBROSPINAL FLUID; CEREBROSPINAL FLUID CONTACTING NUCLEUS; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG WITHDRAWAL; MORPHINE ADDICTION; NERVE CELL; NEUROPATHIC PAIN; NONHUMAN; PATHOPHYSIOLOGY; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ANIMALS; FLUORESCENT ANTIBODY TECHNIQUE; MALE; MORPHINE DEPENDENCE; PERIAQUEDUCTAL GRAY; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANCE P;

EID: 78650703241     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.11.026     Document Type: Article

References (46)

1. Budantsev A., Kisliuk O.S., Shul'govskii V.V., Rykunov D.S., Iarkov A.V. The brain in stereotaxic coordinates (a textbook for colleges). Zh. Vyssh. Nerv. Deiat. Im. I.P. Pavlova 1993, 43:1045-1051.
2. Calle M., Claassen I.E., Veening J.G., Kozicz T., Roubos E.W., Barendregt H.P. Opioid peptides, CRF, and urocortin in cerebrospinal fluid-contacting neurons in Xenopus laevis. Ann. N.Y. Acad. Sci. 2005, 1040:249-252.
3. Cao J.L, He J.H., Ding H.L., Zeng Y.M. Activation of the spinal ERK signaling pathway contributes naloxone-precipitated withdrawal in morphine-dependent rats. Pain 2005, 118:336-349.
4. Cao J.L., Liu H.L., Wang J.K., Zeng Y.M. Cross talk between nitric oxide and ERK1/2 signaling pathway in the spinal cord mediates naloxone-precipitated withdrawal in morphine-dependent rats. Neuropharmacology 2006, 51:315-326.
5. Chaplan S.R., Bach F.W., Pogrel J.W., Chung J.M., Yaksh T.L. Quantitative assessment of tactile allodynia in the rat paw. J. Neurosci. Methods 1994, 53:55-63.
6. Chen Y., Sommer C. The role of mitogen-activated protein kinase (MAPK) in morphine tolerance and dependence. Mol. Neurobiol. 2009, 40:101-107.
7. Cheppudira B.P. Characterization of hind paw licking and lifting to noxious radiant heat in the rat with and without chronic inflammation. J. Neurosci. Methods 2006, 155:122-125.
8. Chou W.B., Zeng Y.M., Duan S.M., Zhou W.H., Gu J., Yang G.D. M2 muscarinic receptor of spinal cord mediated increase of nNOS expression in locus coeruleus during morphine withdrawal. Acta Pharmacol. Sin. 2002, 23:691-697.
9. Commons K.G. Neuronal pathways linking substance P to drug addiction and stress. Brain Res. 2010, 1314:175-182.
10. Dong H., Sun H., Magal E., Ding X., Kumar G.N., Chen J.J., Johnson E.J., Manning B.H. Inflammatory pain in the rabbit: a new, efficient method for measuring mechanical hyperalgesia in the hind paw. J. Neurosci. Methods 2008, 168:76-87.
11. Du J, Yang X., Zhang L., Zeng Y. Expression of TRPM8 in the distal cerebrospinal fluid-contacting neurons in the brain mesencephalon of rats. Cerebrospinal Fluid Res. 2009, 6:3.
12. Hargreaves K., Dubner R., Brown F., Flores C., Joris J. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 1988, 32:77-88.
13. Ikeda H., Heinke B., Ruscheweyh R., Sandkuhler J. Synaptic plasticity in spinal lamina I projection neurons that mediate hyperalgesia. Science 2003, 299:1237-1240.
14. Ikeda H., Kiritoshi T., Murase K. Synaptic plasticity in the spinal dorsal horn. Neurosci. Res. 2009, 64:133-136.
15. Jessell T.M., Iversen L.L. Opiate analgesics inhibit substance P release from rat trigeminal nucleus. Nature 1977, 268:549-551.
16. Kahn L., Alonso G., Normand E., Manzoni O.J. Repeated morphine treatment alters polysialylated neural cell adhesion molecule, glutamate decarboxylase-67 expression and cell proliferation in the adult rat hippocampus. Eur. J. Neurosci. 2005, 21:493-500.
17. Liang D, Zhang L., Qing C., Zeng Y. The ultrastructure of the distal CSF-contacting neurons in the dorsal raphe and the relationships with their surrounding tissues. Acta Anat. Sin. 2007, 38:410-413.
18. Lu X., Geng X., Zhang L., Zeng Y. The methodology for labeling the distal cerebrospinal fluid-contacting neurons in rats. J. Neurosci. Methods 2008, 168:98-103.
19. Lu X., Geng X., Zhang L., Zeng Y., Dong H., Yu H., Substance P expression in the distal cerebrospinal fluid-contacting neurons and spinal trigeminal nucleus in formalin-induced the orofacial inflammatory pain in rats. Brain Res. Bull. 2009, 78:139-144.
20. Lu X., Geng X., Zhang L., Zeng Y. Intrathecal levobupivacaine downregulates substance P expression in the distal cerebrospinal fluid contacting neuron for formalin-induced inflammatory pain in rats. Chin. Pharmacol. Bull. 2008, 24:191-196.
21. Madhavan A., He L., Stuber G.D., Bonci A., WhistlerF J.L. micro-Opioid receptor endocytosis prevents adaptations in ventral segmental area GABA transmission induced during naloxone-precipitated morphine withdrawal. J. Neurosci. 2010, 30:3276-3286.
22. Murtra P., Sheasby A.M., Hunt S.P., De Felipe C. Rewarding effects of opiates are absent in mice lacking the receptor for substance P. Nature 2000, 405:180-183.
23. Nyberg F. The role of the somatotrophic axis in neuroprotection and neuroregeneration of the addictive brain. Int. Rev. Neurobiol. 2009, 88:399-427.
24. Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates, Compact 1997, Academic Press, San Diego. 3rd ed.
25. Pineda J., Torrecilla M., Martin-Ruiz R., Ugedo L. Attenuation of withdrawal-induced hyperactivity of locus coeruleus neurones by inhibitors of nitric oxide synthase in morphine-dependent rats. Neuropharmacology 1998, 37:759-767.
26. Qin C., Zhang L., Liang D., Zeng Y. The nNOS expression in rat distal CSF contacting neurons and its relationship with morphine withdrawal. Chin. Pharmacol. Bull. 2007, 23:1326-1332.
27. Qin C., Zhang L., Zeng Y. The lesion of CSF contacting neurons in rat brain parenchyma inhibits the development of morphine dependence and withdrawal. Chin. J. Appl. Physiol. 2007, 23:286-291.
28. Salmanzadeh F., Fathollahi Y., Semnanian S., Shafizadeh M., Kazemnejad A. Dependence on morphine leads to a prominent sharing among the different mechanisms of long-term potentiation in the CA1 region of rat hippocampus. Brain Res. 2003, 963:93-100.
29. Tiong G.K., Pierce T.L., Olley J.E. Sub-chronic exposure to opiates in the rat: effects on brain levels of substance P and calcitonin gene-related peptide during dependence and withdrawal. J. Neurosci. Res. 1992, 32:569-575.
30. Trang T., Quirion R., Jhamandas K. The spinal basis of opioid tolerance and physical dependence: involvement of calcitonin gene-related peptide, substance P, and arachidonic acid-derived metabolites. Peptides 2005, 26:1346-1355.
31. Trang T., Sutak M., Quirion R., Jhamandas K. The role of spinal neuropeptides and prostaglandins in opioid physical dependence. Br. J. Pharmacol. 2002, 136:37-48.
32. Vera-Portocarrero L.P., Zhang E.T., King T., Ossipov M.H., Vanderah T.W., Lai J., Porreca F. Spinal NK-1 receptor expressing neurons mediate opioid-induced hyperalgesia and antinociceptive tolerance via activation of descending pathways. Pain 2007, 129:35-45.
33. Vigh-Teichmann I., Vigh B. The cerebrospinal fluid-contacting neuron: a peculiar cell type of the central nervous system. Immunocytochemical aspects. Arch. Histol. Cytol. 1989, 52(Suppl):195-207.
34. Vigh B., Manzano e Silva M.J., Frank C.L., Vincze C., Czirok S.J., Szabo A., Lukats A., Szel A. The system of cerebrospinal fluid-contacting neurons. Its supposed role in the nonsynaptic signal transmission of the brain. Histol. Histopathol. 2004, 19:607-628.
35. Wang M., Zhang L. Methodological comparison on the tracing CSF-SNs with HRP. Acta Acad. Med. Xuzhou, China 1992, 12:286-288.
36. Wiley R.G., Lappi D.A. Targeting neurokinin-1 receptor-expressing neurons with [Sar9,Met(O2)11 substance P-saporin. Neurosci. Lett. 1999, 277:1-4.
37. Yaksh T.L., Jessell T.M., Gamse R., Mudge A.W., Leeman S.E. Intrathecal morphine inhibits substance P release from mammalian spinal cord in vivo. Nature 1980, 286:155-157.
38. Yang S.N., Huang L.T., Wang C.L., Chen W.F., Yang C.H., Lin S.Z., Lai M.C., Chen S.J., Tao P.L. Prenatal administration of morphine decreases CREBSerine-133 phosphorylation and synaptic plasticity range mediated by glutamatergic transmission in the hippocampal CA1 area of cognitive-deficient rat offspring. Hippocampus 2003, 13:915-921.
39. Yang S.N., Liu C.A., Chung M.Y., Huang H.C., Yeh G.C., Wong C.S., Lin W.W., Yang C.H., Tao P.L. Alterations of postsynaptic density proteins in the hippocampus of rat offspring from the morphine-addicted mother: beneficial effect of dextromethorphan. Hippocampus 2006, 16:521-530.
40. Yu Y.J., Arttamangkul S., Evans C.J., Williams J.T., von Zastrow M. Neurokinin 1 receptors regulate morphine-induced endocytosis and desensitization of mu-opioid receptors in CNS neurons. J. Neurosci. 2009, 29:222-233.
41. Zhang L., Chen Q.P., Wang J.K., Zhang L.C., Zeng Y.M. Effects of morphine-dependent and withdrawal on activation of the distal cerebrospinal fluid contacting neurons' phosphorylation CREB in rat brain. Neurol Res. 2009, 31:738-742.
42. Zhang L.C., Zeng Y.M., Ting J., Cao J.P., Wang M.S. The distributions and signaling directions of the cerebrospinal fluid contacting neurons in the parenchyma of a rat brain. Brain Res. 2003, 989:1-8.
43. Zhou Q., Carlsson A., Botros M., Fransson R., Sandstrom A., Gordh T., Hallberg M., Nyberg F. The C-terminal amidated analogue of the substance P (SP) fragment SP(1-7) attenuates the expression of naloxone-precipitated withdrawal in morphine dependent rats. Peptides 2009, 30:2418-2422.
44. Zhou Q., Karlsson K., Liu Z., Johansson P., Le Greves M., Kiuru A., Nyberg F. Substance P endopeptidase-like activity is altered in various regions of the rat central nervous system during morphine tolerance and withdrawal. Neuropharmacology 2001, 41:246-253.
45. Zhou Y., Bendor J.T., Yuferov V., Schlussman S.D., Ho A., Kreek M.J. Amygdalar vasopressin mRNA increases in acute cocaine withdrawal: evidence for opioid receptor modulation. Neuroscience 2005, 134:1391-1397.
46. Zhou Y., Leri F., Cummins E., Hoeschele M., Kreek M.J. Involvement of arginine vasopressin and V1b receptor in heroin withdrawal and heroin seeking precipitated by stress and by heroin. Neuropsychopharmacology 2008, 33:226-236.