The C-terminal amidated analogue of the substance P (SP) fragment SP1-7 attenuates the expression of naloxone-precipitated withdrawal in morphine dependent rats

Peptides

Volumn 30, Issue 12, 2009, Pages 2418-2422

  Zhou, Qin ^a   Carlsson, Anna ^a   Botros, Milad ^a   Fransson, Rebecca ^a   Sandström, Anja ^a   Gordh, Torsten ^b   Hallberg, Mathias ^a   Nyberg, Fred ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Morphine; Opiate; Rat; Sigma receptor; SP1 7 amide; Substance P (SP); Withdrawal

Indexed keywords

MORPHINE; N ALLYLNORMETAZOCINE; NALOXONE; SIGMA OPIATE RECEPTOR; SUBSTANCE P [1-7];

AMIDATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BRAIN HOMOGENATE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DRUG POTENCY; MALE; MORPHINE ADDICTION; NONHUMAN; PRIORITY JOURNAL; PROVOCATION TEST; RAT; RECEPTOR BINDING; TREATMENT OUTCOME; WITHDRAWAL SYNDROME;

ANIMALS; ANTIPSYCHOTIC AGENTS; BRAIN; MALE; MORPHINE DEPENDENCE; NALOXONE; PEPTIDE FRAGMENTS; PHENAZOCINE; RATS; RATS, WISTAR; SUBSTANCE P; SUBSTANCE WITHDRAWAL SYNDROME;

RATTUS;

EID: 70449637482     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2009.08.009     Document Type: Article

References (25)

1. Aanonsen L.M., and Seybold V.S. Phencyclidine and sigma receptors in rat spinal cord: binding characterization and quantitative autoradiography. Synapse 4 (1989) 1-10
2. 1-7 in the rat spinal cord. Peptides 27 (2006) 753-759
3. Botros M., Johansson T., Zhou Q., Lindeberg G., Tömböly C., Tóth G., et al. Endomorphins interact with the substance P (SP) aminoterminal SP(1-7) binding in the ventral tegmental area of the rat brain. Peptides 29 (2008) 1820-1824
4. Fransson R., Botros M., Nyberg F., Lindeberg G., Sandström A., and Hallberg M. Small peptides mimicking substance P (1-7) and encompassing a C-terminal amide functionality. Neuropeptides 42 (2008) 31-37
5. Hanner M., Moebius F.F., Flandorfer A., Streissnig J., Kempner E., et al. Purification, molecular cloning, and expression of the mammalian sigma-1 receptor site. Proc Natl Acad Sci USA 93 (1996) 8072-8077
6. Inturissi C.E. Clinical pharmacology of opioids for pain. Clin J Pain 18 4 Suppl (2002) S3-S13 [review]
7. Iwamoto E.T. Locomotor activity and antinociception after putative Mu, Kappa and Sigma opioid agonists in the rat: influence of dopaminergic agonists and antagonists. J Pharm Exp Pher 217 (1981) 451-460
8. Koob G.F., Wall T.L., and Bloom F.E. Nucleus accumbens as a substrate for the aversive stimulus effects of opiate withdrawal. Psychopharmacology (Berl) 98 (1989) 530-534
9. Koob G.F., and Le Moal M. Neurobiology of addiction (2006), Academic Press Elsevier, San Diego, CA, USA
10. 3H]3-(3-hydroxyphenyl)-N-(1-propyl)piperidine. Proc Natl Acad Sci USA 81 (1984) 4983-4987
11. Larson A.A., and Sun X. Regulation of sigma activity by the amino-terminus of substance P in the mouse spinal cord: involvement of phencyclidine (PCP) sites not linked to N-methyl d-aspartate (NMDA) activity. Neuropharmacology 32 (1993) 909-917
12. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with the Folin phenol reagent. J Biol Chem 193 (1951) 265-275
13. Martin W.R., Eades C.G., Thompson J.A., Huppler R.E., and Gilbert P.E. The effects of morphine and nalorphine-like drugs in the nondependent and morphine-dependent chronic spinal dog. J Pharmacol Exp Ther 197 (1976) 517-553
14. Nestler E.J. Molecular mechanisms of drug addiction. J Neurosci 12 7 (1992) 2439-2450
15. Tam S.W. Naloxone-inaccessible σ-receptor in rat central nervous system. Proc Natl Acad Sci USA 80 (1983) 6703-6707
16. 3H]Haloperidol binding in guinea pig brain membranes. Proc Natl Acad Sci USA 81 (1984) 5618-5621
17. Terashvili M., Wu H., More R.M., Harder D.R., and Tseng L.F. (+)-Morphine and (-)-morphine stereoselectively attenuate the (-)-morphine-produced tail-flick inhibition via the naloxone-sensitive sigma receptor in the ventral periaqueductal gray of the rat. Eur J Pharmacol 571 (2007) 1-7
18. 3H]-SKF-10047-binding protein partially purified from rat liver and rat brain membranes: a opioid/sigma receptor?. Synapse 25 (1997) 117-124
19. Walker J.M., Bowen W.D., Walker W.O., Matsumoto R.R., De Costa B., and Rice K.C. Sigma receptors: biology and function. Pharmacol Rev 42 (1990) 355-402
20. Wu H.-e., Hong J.-S., and Tseng L.F. Stereoselective action of (+)-morphine over (-)-morphine in attenuating the (-)-morphine-produced antinociception via the naloxone-sensitive sigma receptor in the mouse. Eur J Pharmacol 571 (2007) 145-151
21. Zhou Q., Liu Z., Ray A., Huang W., Karlsson K., and Nyberg F. Alteration in the brain content of substance P (1-7) during withdrawal in morphine-dependent rats. Neuropharmacology 37 (1998) 1545-1552
22. Zhou Q., Karlsson K., Liu Z., Johansson P., Le Grevès M., Kiriu A., et al. Substance P endopeptidase-like activity is altered in various regions of the rat central nervous system during morphine tolerance and withdrawal. Neuropharmacology 41 (2001) 246-253
23. 1-7 into the ventral tegmantal area modulates the levels of nucleus accumbens dopamine and dihydroxyphenylacetic acid in male rats during morphine withdrawal. Neurosci Lett 320 (2002) 117-120
24. Zhou Q., Frandberg P.A., Kindlundh A.M.S., Le Grevès P., and Nyberg F. Substance P(1-7) affects the expression of dopamine D2 receptor mRNA in male rat brain during morphine withdrawal. Peptides 24 (2003) 147-153
25. Zhou Q., Kindlundh A.M.S., Hallberg M., and Nyberg F. The substance P (SP) heptapeptide fragment SP(1-7) alters the density of dopamine receptors in rat brain mesocorticolimbic structures during morphine withdrawal. Peptides 64 (2004) 1951-1957