Direct inhibition of human RANK + osteoclast precursors identifies a homeostatic function of IL-1β

Journal of Immunology

Volumn 185, Issue 10, 2010, Pages 5926-5934

  Lee, Bitnara ^a   Kim, Tae Hwan ^a   Jun, Jae Bum ^a   Yoo, Dae Hyun ^a   Woo, Jin Hyun ^b   Choi, Sung Jae ^b   Lee, Young Ho ^b   Song, Gwan Gyu ^b   Sohn, Jeongwon ^b   Park Min, Kyung Hyun ^c   Ivashkiv, Lionel B ^c   Ji, Jong Dae ^b  

^a Hanyang University   (South Korea)

^b Korea University College of Medicine   (South Korea)

^c HOSPITAL FOR SPECIAL SURGERY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL RECEPTOR; COLONY STIMULATING FACTOR RECEPTOR; INTERLEUKIN 1; INTERLEUKIN 1BETA; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1;

ARTICLE; BONE DESTRUCTION; BONE MARROW CELL; CELL DIFFERENTIATION; CONTROLLED STUDY; HOMEOSTASIS; HUMAN; HUMAN CELL; MACROPHAGE; MOLECULAR MECHANICS; MONOCYTE; MULTINUCLEAR CELL; OSTEOCLAST; OSTEOCLASTOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SYNOVIUM;

ARTHRITIS, RHEUMATOID; BONE RESORPTION; CELL DIFFERENTIATION; CELL SEPARATION; FLOW CYTOMETRY; HOMEOSTASIS; HUMANS; IMMUNOBLOTTING; INFLAMMATION; INTERLEUKIN-1BETA; MACROPHAGES; MONOCYTES; OSTEOCLASTS; RANK LIGAND; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B; STEM CELLS; SYNOVIAL MEMBRANE;

EID: 78650661468     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1001591     Document Type: Article

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