Imatinib response in two GIST patients carrying two hitherto functionally uncharacterized PDGFRA mutations: An imaging, biochemical and molecular modeling study

International Journal of Cancer

Volumn 128, Issue 4, 2011, Pages 983-990

  Dileo, Palma ^a   Pricl, Sabrina ^b   Tamborini, Elena ^a   Negri, Tiziana ^a   Stacchiotti, Silvia ^a   Gronchi, Alessandro ^a   Posocco, Paola ^b   Laurini, Erik ^b   Coco, Paola ^a   Fumagalli, Elena ^a   Casali, Paolo G ^a   Pilotti, Silvana ^a  

^a NATIONAL CANCER INSTITUTE   (Italy)

^b UNIVERSITY OF TRIESTE   (Italy)

Author keywords

GIST; Imatinib mesylate; PDGFRA; targeted therapy

Indexed keywords

IMATINIB; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR;

ADULT; AGED; ARTICLE; CANCER REGISTRY; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; FEMALE; GASTROINTESTINAL STROMAL TUMOR; GENE MUTATION; HUMAN; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULAR DYNAMICS; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; TUMOR VOLUME;

ANTINEOPLASTIC AGENTS; FEMALE; GASTROINTESTINAL STROMAL TUMORS; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MIDDLE AGED; MODELS, MOLECULAR; MUTATION; PIPERAZINES; POSITRON-EMISSION TOMOGRAPHY; PROGNOSIS; PROTEIN CONFORMATION; PYRIMIDINES; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; TOMOGRAPHY, X-RAY COMPUTED; TUMOR MARKERS, BIOLOGICAL;

EID: 78650597144     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.25418     Document Type: Article

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