Esculetin-induced protection of human hepatoma HepG2 cells against hydrogen peroxide is associated with the Nrf2-dependent induction of the NAD(P)H: Quinone oxidoreductase 1 gene

Toxicology and Applied Pharmacology

Volumn 250, Issue 2, 2011, Pages 130-136

  Subramaniam, Sudhakar R ^a   Ellis, Elizabeth M ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

Esculetin; NAD(P)H: quinone oxidoreductase; NQO1; Nrf2; Oxidative stress

Indexed keywords

BIOCHEMICAL MARKER; ESCULETIN; GLUTATHIONE; HYDROGEN PEROXIDE; MESSENGER RNA; QUERCETIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; TRANSCRIPTION FACTOR NRF2;

ADAPTATION; ARTICLE; BIOACCUMULATION; CELL NUCLEUS; CELL STRAIN HEPG2; CELL VIABILITY; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INDUCTION; GENE EXPRESSION; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PROTEIN EXPRESSION;

ANTIOXIDANTS; CELL DEATH; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; GLUTATHIONE; HEP G2 CELLS; HUMANS; HYDROGEN PEROXIDE; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; UMBELLIFERONES;

EID: 78650547215     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2010.09.025     Document Type: Article

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