Molecular modeling and UV-vis spectroscopic studies on the mechanism of action of reversed chloroquine (RCQ)

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 1, 2011, Pages 250-254

  Otelo, Vanessa A ^a   Sant'Ana, Antonio C ^a   De Faria, Dalva L A ^a   Menezes, Carla M S ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Antimalarial; Chloroquine; Heme; Multiple ligand; Reversed chloroquine

Indexed keywords

CHLOROQUINE; HEME; REVERSED CHLOROQUINE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIUM ISOLATE; CHEMICAL STRESS; DRUG MECHANISM; DRUG TARGETING; MOLECULAR INTERACTION; MOLECULAR MODEL; PLASMODIUM FALCIPARUM; ULTRAVIOLET SPECTROSCOPY;

AMINOQUINOLINES; ANTIMALARIALS; CHLOROQUINE; DIBENZAZEPINES; HEMIN; HYDROGEN-ION CONCENTRATION; IMIPRAMINE; MOLECULAR DYNAMICS SIMULATION; PLASMODIUM FALCIPARUM; SPECTROPHOTOMETRY, ULTRAVIOLET;

PLASMODIUM FALCIPARUM;

EID: 78650516728     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.11.019     Document Type: Article

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