Prediction of drug intestinal absorption by new linear and non-linear QSPR

European Journal of Medicinal Chemistry

Volumn 46, Issue 1, 2011, Pages 218-228

  Talevi, Alan ^a   Goodarzi, Mohammad ^b   Ortiz, Erlinda V ^c   Duchowicz, Pablo R ^b   Bellera, Carolina L ^a   Pesce, Guido ^d   Castro, Eduardo A ^b   Bruno Blanch, Luis E ^a  

^a FACULTAD DE CIENCIAS EXACTAS   (Argentina)

^b Universidad Nacional de Río Cuarto Consejo Nacional de Investigaciones Científicas y Técnicas   (Argentina)

^c UNIVERSIDAD NACIONAL DE CATAMARCA   (Argentina)

^d ANMAT   (Argentina)

Author keywords

ADME properties; Drug intestinal absorption; Model's applicability domain; Molecular descriptors; QSPR theory; Replacement method

Indexed keywords

ACAMPROSATE; ACARBOSE; ADEFOVIR; AMPHOTERICIN; AMYGDALIN; AZTREONAM; CEFODIZIME; CEFTRIAXONE; CEFUROXIME; CIDOFOVIR; CROMOGLYCATE DISODIUM; DOXORUBICIN; EDETIC ACID; FOSCARNET; GANCICLOVIR; GENTAMICIN; IMIPENEM; IOHEXOL; IOTROXIC ACID; KANAMYCIN; MANNITOL; MEROPENEM; MEZLOCILLIN; MITOXANTRONE; NEDOCROMIL; NEOMYCIN; NETILMICIN; OLSALAZINE; PAMIDRONIC ACID; UNINDEXED DRUG;

ARTICLE; COMPUTER MODEL; DRUG ABSORPTION; HIGH THROUGHPUT SCREENING; INTESTINE ABSORPTION; NONLINEAR SYSTEM; QUANTITATIVE STRUCTURE PROPERTY RELATION; STATISTICAL MODEL;

EID: 78650516038     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.11.005     Document Type: Article

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