Synthesis and 11β hydroxysteroid dehydrogenase 1 inhibition of thiazolidine derivatives with an adamantyl group

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 1, 2011, Pages 435-439

  Kwon, Sung Wook ^a   Kang, Seung Kyu ^b   Lee, Jae Hong ^a   Bok, Joo Hwan ^b   Kim, Chi Hyun ^b   Rhee, Sang Dal ^b   Jung, Won Hoon ^b   Kim, Hee Youn ^b   Bae, Myung Ae ^b   Song, Jin Sook ^b   Ha, Duck Chan ^a   Cheon, Hyae Gyoung ^b   Kim, Ki Young ^b   Ahn, Jin Hee ^b  

^a Korea University   (South Korea)

^b Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

11beta HSD1; Adamantyl; Diabetes; Thiazolidine

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 1; 2 FLUOROPHENYLSULFONYL DERIVATIVE; ADAMANTANE DERIVATIVE; THAIZOLIDINE 2 CARBOXYLIC ACID ADAMANTYLAMIDE; THIAZOLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; DRUG SYNTHESIS; ENZYME INHIBITION; GLYCEMIC CONTROL; HAPLORHINI; HUMAN; NONHUMAN; RAT;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2; ADAMANTANE; ANIMALS; ENZYME INHIBITORS; HAPLORHINI; HUMANS; MICE; MICROSOMES, LIVER; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLIDINES;

MUS; RATTUS;

EID: 78650509855     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.10.123     Document Type: Article

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