SCOPUS 정보 검색 플랫폼

Volumn 2, Issue 10, 2010, Pages 1542-1549

Rapid structure determination of microgram-level drug metabolites using HPLC-MS, fraction collection and NMR spectroscopy

(6) Johnson, Kim A a Liu, Xiaohong a Huang, Stella a Roongta, Vikram a Humphreys, W Griffith a Shu, Yue Zhong a

a BRISTOL MYERS SQUIBB (United States)

Author keywords

[No Author keywords available]

Indexed keywords

96-WELL PLATE; CRYOGENIC PROBES; CYCLE TIME; DRUG CANDIDATES; DRUG DISCOVERY; DRUG METABOLITES; FRACTION COLLECTION; HEPATOCYTES; HIGH-FIELD NMR; HPLC-MS; HPLC-MS/MS; IN-VITRO; METABOLITE IDENTIFICATION; METHOD DEVELOPMENT; MODEL COMPOUND; NMR DATA; NMR SOLVENTS; NMR SPECTROSCOPY; NMR SPECTRUM; OPTIMISATIONS; ROBUST METHODS; SAMPLE PREPARATION; SOLVENT REMOVAL; STRUCTURE DETERMINATION; TRAZODONE; UNSTABLE COMPOUNDS;

BIOMOLECULES; DEUTERIUM; LEAD COMPOUNDS; METABOLITES; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SIGNAL TO NOISE RATIO; SPECTROMETERS; TURNAROUND TIME;

METABOLISM;

EID: 78650459028 PISSN: 17599660 EISSN: 17599679 Source Type: Journal
DOI: 10.1039/c0ay00290a Document Type: Article

Times cited : (6)

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