HPLC-SPE-NMR in pharmaceutical development: Capabilities and applications

Magnetic Resonance in Chemistry

Volumn 43, Issue 9, 2005, Pages 762-770

  Sandvoss, Martin ^a   Bardsley, Ben ^a   Beck, Tony L ^a   Lee Smith, Emma ^a   North, Stephanie E ^a   Moore, Peter J ^a   Edwards, Andrew J ^a   Smith, Richard J ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Drug development; HPLC SPE NMR; Hyphenated techniques; Metabolite identification; Solid phase extraction

Indexed keywords

DRUG PRODUCTS; EXTRACTION; METABOLITES; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHASE SEPARATION; SIGNAL TO NOISE RATIO;

DRUG DEVELOPMENT; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY-SOLID PHASE EXTRACTION-NMR SPECTROSCOPY; HYPHENATED TECHNIQUES; METABOLITE IDENTIFICATION; MULTIPLE-PEAK; NMR-SPECTROSCOPY; POLAR COMPOUNDS; SOLID-PHASE EXTRACTION;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 23644448444     PISSN: 07491581     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrc.1615     Document Type: Article

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