Fab′-induced folding of antigenic N-terminal peptides from intrinsically disordered HIV-1 Tat revealed by X-ray crystallography

Journal of Molecular Biology

Volumn 405, Issue 1, 2011, Pages 33-42

  Serrière, Jennifer ^a   Dugua, Jean Marc ^b   Bossus, Marc ^b   Verrier, Bernard ^a   Haser, Richard ^a   Gouet, Patrice ^a   Guillon, Christophe ^a  

^a INSTITUT DE BIOLOGIE ET CHIMIE DES PROTÉINES   (France)

^b BIOMÉRIEUX   (France)

Author keywords

crystal structure; Fab ; HIV 1 Tat; induced folding; intrinsically disordered protein

Indexed keywords

IMMUNOGLOBULIN F(AB) FRAGMENT; MONOCLONAL ANTIBODY; PHENYLALANINE; TRANSACTIVATOR PROTEIN; TRYPTOPHAN; EPITOPE; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; VIRUS ANTIGEN;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANTIGEN BINDING; ARTICLE; CLINICAL EVALUATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN SYNTHESIS; X RAY CRYSTALLOGRAPHY; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; EPITOPE MAPPING; GENETICS; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN TERTIARY STRUCTURE; REVIEW; SITE DIRECTED MUTAGENESIS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIBODIES, MONOCLONAL; ANTIGENS, VIRAL; CRYSTALLOGRAPHY, X-RAY; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPE MAPPING; EPITOPES; HIV ANTIBODIES; HIV-1; IMMUNOGLOBULIN FAB FRAGMENTS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS;

EID: 78650414170     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2010.10.033     Document Type: Article

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