Poly[(5-methyl-5-allyloxycarbonyl-trimethylene carbonate)-co-(5,5-dimethyl- trimethylene carbonate)] with grafted polyethylenimine as biodegradable polycations for efficient gene delivery

Biomacromolecules

Volumn 11, Issue 11, 2010, Pages 3028-3035

  He, Feng ^a   Wang, Chang Fang ^a   Jiang, Tao ^a   Han, Bing ^a   Zhuo, Ren Xi ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

[CARBONYL; ALLYLOXYCARBONYL; CELLULAR UPTAKE; DEGRADATION RATE; DNA BINDING; DNA BINDING ABILITY; GENE DELIVERY; GENE TRANSFECTION; LOW MOLECULAR WEIGHT; NANO-SIZED PARTICLES; NONVIRAL VECTORS; PHYSICOCHEMICAL PROPERTY; POLYCATIONS; POLYETHYLENIMINES; POLYPLEXES; PORCINE PANCREAS LIPASE; PRE-INCUBATION; T CELLS; TRIMETHYLENE CARBONATE;

CARBONATES; CARBONATION; COPOLYMERIZATION; COPOLYMERS; DEGRADATION; DNA; GENE THERAPY; GENE TRANSFER; POLYCARBONATES; POLYDISPERSITY;

GRAFTING (CHEMICAL);

COPOLYMER; POLYCARBONATE; POLYCATION; POLYETHYLENEIMINE; TRIACYLGLYCEROL LIPASE; VIRUS VECTOR; DNA; POLY((5-METHYL-5-ALLYLOXYCARBONYLTRIMETHYLENE CARBONATE)-CO-(5,5-DIMETHYLTRIMETHYLENE CARBONATE))-G-POLYETHYLENIMINE; POLYAMINE; POLYCATIONS; POLYESTER;

ARTICLE; CYTOTOXICITY; DNA BINDING; EPOXIDATION; GENE TARGETING; GENETIC TRANSFECTION; PHYSICAL CHEMISTRY; POLYMERIZATION; PRIORITY JOURNAL; ANALOGS AND DERIVATIVES; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; GENE TRANSFER; GENETICS; HEK293 CELL LINE; HUMAN; PARTICLE SIZE; STRUCTURE ACTIVITY RELATION; SURFACE PROPERTY; SYNTHESIS;

SUS;

CELL SURVIVAL; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE TRANSFER TECHNIQUES; HEK293 CELLS; HUMANS; MOLECULAR STRUCTURE; PARTICLE SIZE; POLYAMINES; POLYESTERS; POLYETHYLENEIMINE; STRUCTURE-ACTIVITY RELATIONSHIP; SURFACE PROPERTIES;

EID: 78650387968     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm1008525     Document Type: Article

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