Polymorphisms in base excision repair genes as colorectal cancer risk factors and modifiers of the effect of diets high in red meat

Cancer Epidemiology Biomarkers and Prevention

Volumn 19, Issue 12, 2010, Pages 3167-3173

  Brevik, Asgeir ^a,g   Joshi, Amit D ^a   Corral, Román ^a   Onland Moret, N Charlotte ^a,h   Siegmund, Kimberly D ^a   Le Marchand, Loïc ^b   Baron, John A ^c   Martinez, Maria Elena ^d   Haile, Robert W ^a   Ahnen, Dennis J ^e   Sandler, Robert S ^f   Lance, Peter ^d   Stern, Mariana C ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF HAWAII CANCER CENTER   (United States)

^c DARTMOUTH MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF ARIZONA   (United States)

^e UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^g NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

^h UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ARGININE; ASPARTIC ACID; CYSTEINE; FREE RADICAL; GLUTAMIC ACID; GLUTAMINE; HISTIDINE; SERINE; TRYPTOPHAN; VALINE;

APEX1 GENE; ARTICLE; CODON; COLON CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; DIETARY INTAKE; DNA DAMAGE; EXCISION REPAIR; GENETIC POLYMORPHISM; GENOTYPE ENVIRONMENT INTERACTION; HIGH TEMPERATURE; HUMAN; OGG1 GENE; ONCOGENE; OXIDATIVE STRESS; PARP GENE; POULTRY; PRIORITY JOURNAL; RED MEAT; RISK FACTOR; RISK REDUCTION; SIBLING; SINGLE NUCLEOTIDE POLYMORPHISM; XRCC1 GENE;

ANIMALS; CASE-CONTROL STUDIES; COLORECTAL NEOPLASMS; DIET; DNA GLYCOSYLASES; DNA REPAIR; DNA REPAIR ENZYMES; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; DNA-BINDING PROTEINS; GENOTYPE; HUMANS; MEAT; ODDS RATIO; POLY(ADP-RIBOSE) POLYMERASES; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 78650387028     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-10-0606     Document Type: Article

References (24)

1. Food, Nutrition, Physical Activity and the Prevention of Cancer: A Global Perspective. London: World Cancer Research Fund/American Institute for Cancer Research; 2007.
2. Joshi AD, Corral R, Siegmund KD, et al. Red meat and poultry intake, polymorphisms in the nucleotide excision repair and mismatch repair pathways, and colorectal cancer risk. Carcinogenesis 2009;30:472-9.
3. Butler LM, Sinha R, Millikan RC, et al. Heterocyclic amines, meat intake, and association with colon cancer in a population-based study. Am J Epidemiol 2003;157:434-45.
4. Nowell S, Coles B, Sinha R, et al. Analysis of total meat intake and exposure to individual heterocyclic amines in a case-control study of colorectal cancer: contribution of metabolic variation to risk. Mutat Res 2002;506-507:175-85.
5. Knize MG, Salmon CP, Pais P, Felton JS. Food heating and the formation of heterocyclic aromatic amine and polycyclic aromatic hydrocarbon mutagens/carcinogens. Adv Exp Med Biol 1999;459: 179-93.
6. Bingham SA, Hughes R, Cross AJ. Effect of white versus red meat on endogenous N-nitrosation in the human colon and further evidence of a dose response. J Nutr 2002;132:3522S-5S.
7. Turesky RJ. Heterocyclic aromatic amine metabolism, DNA adduct formation, mutagenesis, and carcinogenesis. Drug Metab Rev 2002;34:625-50.
8. Yeh CC, Hsieh LL, Tang R, Chang-Chieh CR, Sung FC. MS-920: DNA repair gene polymorphisms, diet, and colorectal cancer risk in Taiwan. Cancer Lett 2005;224:279-88.
9. Newcomb PA, Baron J, Cotterchio M, et al. Colon Cancer Family Registry: an international resource for studies of the genetic epidemiology of colon cancer. Cancer Epidemiol Biomarkers Prev 2007;16: 2331-43.
10. Wang XG, Wang ZQ, Tong WM, Shen Y. PARP1 Val762Ala polymorphism reduces enzymatic activity. Biochem Biophys Res Commun 2007;354:122-6.
11. Bibikova M, Chudin E, Arsanjani A, et al. Expression signatures that correlated with Gleason score and relapse in prostate cancer. Genomics 2007;89:666-72.
12. Takanami T, Nakamura J, Kubota Y, Horiuchi S. The Arg280His polymorphism in X-ray repair cross-complementing gene 1 impairs DNA repair ability. Mutat Res 2005;582:135-45.
13. Hadi MZ, Coleman MA, Fidelis K, Mohrenweiser HW, Wilson ID. Functional characterization of Ape1 variants identified in the human population. Nucleic Acids Res 2000;28:3871-9.
14. Hung RJ, Hall J, Brennan P, Boffetta P. Genetic polymorphisms in the base excision repair pathway and cancer risk: a HuGE review. Am J Epidemiol 2005;162:925-42.
15. Khoury MJ, Flanders WD. Nontraditional epidemiologic approaches in the analysis of gene-environment interaction: case-control studies with no controls!Am J Epidemiol 1996;144: 207-13.
16. Nosho K, Yamamoto H, Mikami M, et al. Overexpression of poly(ADP-ribose) polymerase-1 (PARP-1) in the early stage of colorectal carcinogenesis. Eur J Cancer 2006;42:2374-81.
17. Stern MC, Conti DV, Siegmund KD, , et al. DNA repair single-nucleotide polymorphisms in colorectal cancer and their role as modifiers of the effect of cigarette smoking and alcohol in the Singapore Chinese Health Study. Cancer EpidemiolBiomarkers Prev 2007;16:2363-72.
18. Zhang X, Miao X, Liang G, et al. Polymorphisms in DNA base excision repair genes ADPRT and XRCC1 and risk of lung cancer. Cancer Res 2005;65:722-6.
19. Hao B, Wang H, Zhou K, et al. Identification of genetic variants in base excision repair pathway and their associations with risk of esophageal squamous cell carcinoma. Cancer Res 2004;64:4378-84.
20. Lockett KL, Hall MC, Xu J, et al. The ADPRT V762A genetic variant contributes to prostate cancer susceptibility and deficient enzyme function. Cancer Res 2004;64:6344-8.
21. Stern MC, Butler LM, Corral R, et al. Polyunsaturated fatty acids, DNA repair single nucleotide polymorphisms and colorectal cancer in the Singapore Chinese Health Study. J Nutrigenet Nutrigenomics 2009;2:273-9.
22. Pardini B, Naccarati A, Novotny J, et al. DNA repair genetic polymorphisms and risk of colorectal cancer in the Czech Republic. Mutat Res 2008;638:146-53.
23. Kasahara M, Osawa K, Yoshida K, et al. Association of MUTYH Gln324His and APEX1 Asp148Glu with colorectal cancer and smoking in a Japanese population. J Exp Clin Cancer Res 2008; 27:49.
24. Berndt SI, Huang WY, Fallin MD, et al. Genetic variation in base excision repair genes and the prevalence of advanced colorectal adenoma. Cancer Res 2007;67:1395-404.