Anti-inflammatory effects of caper (Capparis spinosa L.) fruit aqueous extract and the isolation of main phytochemicals

Journal of Agricultural and Food Chemistry

Volumn 58, Issue 24, 2010, Pages 12717-12721

  Zhou, Haifeng ^a   Jian, Renji ^a   Kang, Jie ^b   Huang, Xiaoling ^a   Li, Yan ^a   Zhuang, Changlong ^a   Yang, Fang ^a   Zhang, Lele ^a   Fan, Xiao ^a   Wu, Tong ^a   Wu, Xianli ^b  

^a SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY   (China)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

anti inflammatory; Capparis spinosa L.; flavonoid; indole; phenolic acid

Indexed keywords

ANTI-INFLAMMATORIES; CAPPARIS SPINOSA L.; FLAVONOID; INDOLE; PHENOLIC ACIDS;

ADSORPTION; FRUITS; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; ORGANIC ACIDS; PHENOLS; RESINS; RESONANCE; SPECTROSCOPIC ANALYSIS;

SOLVENT EXTRACTION;

ANTIINFLAMMATORY AGENT; CARRAGEENAN; PLANT EXTRACT;

ANIMAL; ARTICLE; CAPPARIS; CHEMICALLY INDUCED DISORDER; CHEMISTRY; DISEASE MODEL; EDEMA; FRUIT; HUMAN; IMMUNOLOGY; ISOLATION AND PURIFICATION; MALE; MOUSE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CAPPARIS; CARRAGEENAN; DISEASE MODELS, ANIMAL; EDEMA; FRUIT; HUMANS; MALE; MICE; PLANT EXTRACTS;

CAPPARIS SPINOSA; MUS;

EID: 78650369926     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf1034114     Document Type: Article

References (29)

1. Tesoriere, L.; Butera, D.; Gentile, C.; Livrea, M. A. Bioactive components of caper (Capparis spinosa L.) from Sicily and antioxidant effects in a red meat simulated gastric digestion J. Agric. Food Chem. 2007, 55, 8465-8471
2. Tlili, N.; Elfalleh, W.; Saadaoui, E.; Khaldi, A.; Triki, S.; Nasri, N. The caper (Capparis L.): Ethnopharmacology, phytochemical and pharmacological properties. Fitoterapia 2010, DOI: 10.1016/j.fitote.2010.09.006.
3. Ageel, A. M.; Parmar, N. S.; Mossa, J. S.; Al-Yahya, M. A.; Al-Said, M. S.; Tariq, M. Anti-inflammatory activity of some Saudi Arabian medicinal plants Agents Actions 1986, 17, 383-384
4. al-Said, M. S.; Abdelsattar, E. A.; Khalifa, S. I.; el-Feraly, F. S. Isolation and identification of an anti-inflammatory principle from Capparis spinosa Pharmazie 1988, 43, 640-641
5. Rimbau, V.; Risco, E.; Canigueral, S. R.; Lglesias, J. Antiinflammatory activity of some extracts from plants used in the traditional medicine of north African countries Phytother. Res. 1996, 10, 421-423
6. Gautam, R.; Jachak, S. M. Recent developments in anti-inflammatory natural products Med. Res. Rev. 2009, 29, 767-820
7. Zhang, X.; Zhu, Z.; Huang, Z.; Tan, P.; Ma, R. Z. Microsatellite genotyping for four expected inbred mouse strains from KM mice J. Genet. Genomics 2007, 34, 214-222
8. Shaaban, M.; Schröder, D.; Shaaban, K. A.; Helmke, E.; Grün-Wollny, I.; Wagner-Döbler, I.; Laatsch, H. Flazin, perlolyrin, and other β-carbolines from marine-derived bacteria Rev Latinoam. Quim. 2007, 35, 58-67
9. Jones, A. J.; Grant, D. M.; Winkley, M. W.; Robins, R. K. Carbon-13 magnetic resonance. XVII. Pyrimidine and purine nucleosides J. Am. Chem. Soc. 1970, 92, 4079-4087
10. Li, Y. Q.; Yang, S. L.; Li, H. R.; Xu, L. Z. Two new alkaloids from Capparis himalayensis Chem. Pharm. Bull. 2008, 56, 189-191
11. Chowdhury, B. K.; Chakraborty, D. P. 3-Formylindole from Murraya exotica Phytochemistry 1971, 10, 481-483
12. Somei, M.; Iwasa, E.; Yamada, F. A. A practical and short access to 4-hydroxy-3-indolecarbaldehyde and its application for the synthesis of pindolol analog Heterocycles 1986, 24, 3065-3069
13. Awaad, A. S.; Maitland, D. J.; Soliman, G. A. Hepatoprotective activity of Schouwia thebica Webb Bioorg. Med. Chem. Lett. 2006, 16, 4624-4628
14. 13C NMR spectra of the flavone apigenin Magn. Reson. Chem. 1986, 24, 879-882
15. Mbouangouere, R. N.; Tane, P.; Ngamga, D.; Ngamga, D.; Djemgou, P.; Choudhary, M. I.; Ngadjui, B. T. Piptaderol from Piptadenia africana Afr. J. Tradit., Complementary Altern. Med. 2007, 4, 294-298
16. Yang, T.; Wang, C.; Liu, H.; Chou, G.; Cheng, X.; Wang, Z. A new antioxidant compound from Capparis spinosa Pharm. Biol. 2010, 48, 589-594
17. Sakushima, A.; Coskun, M.; Maoka, T. Hydroxybenzoic acids from Boreava orientalis Phytochemistry 1995, 40, 257-261
18. Yin, Y. Q.; Huang, X. F.; Kong, L. Y.; Niwa, M. Three new pentasaccharide resin glycosides from the roots of sweet potato (Ipomoea batatas) Chem. Pharm. Bull. 2008, 56, 1670-1674
19. Zhou, H.; Wong, Y. F.; Cai, X.; Liu, Z. Q.; Jiang, Z. H.; Bian, Z. X.; Xu, H. X.; Liu, L. Suppressive effects of JCICM-6, the extract of an anti-arthritic herbal formula, on the experimental inflammatory and nociceptive models in rodents Biol. Pharm. Bull. 2006, 29, 253-260
20. Calis, I.; Kuruuzum, A.; Ruedi, P. 1 H-Indole-3-acetonitrile glycosides from Capparis spinosa fruits Phytochemistry 1999, 50, 1205-1208
21. Calis, I.; Kuruuzum-Uz, A.; Lorenzetto, P. A.; Ruedi, P. (6 S)-Hydroxy-3-oxo-α-ionol glucosides from Capparis spinosa fruits Phytochemistry 2002, 59, 451-457
22. Giuffrida, D.; Salvo, F.; Ziino, M.; Toscano, G.; Dugo, G. Initial investigation on some chemical constituents of capers (Capparis spinosa L.) from the island of Salina Ital. J. Food Sci. 2002, 14, 25-33
23. Matthaus, B.; Ozcan, M. Glucosinolates and fatty acid, sterol, and tocopherol composition of seed oils from Capparis spinosa var. spinosa and Capparis ovata Desf. var. canescens (Coss.) Heywood J. Agric. Food Chem. 2005, 53, 7136-7141
24. Sharaf, M.; El-Ansari, M. A.; Saleh, N. A. M. Quercetin triglycoside from Capparis spinosa Fitoterapia 2000, 71, 46-49
25. Fu, X. P.; Wu, T.; Abdurahim, M.; Su, Z.; Hou, X. L.; Aisa, H. A.; Wu, H. New spermidine alkaloids from Capparis spinosa roots Phytochem. Lett. 2008, 1, 59-62
26. Romeo, V.; Ziino, M.; Giuffrida, D.; Condurso, C.; Verzer, A. Flavour profile of capers (Capparis spinosa L.) from the Eolian Archipelago by HS-SPME/GC-MS Food Chem. 2007, 101, 1272-1278
27. Serafini, M.; Peluso, I.; Raguzzini, A. Flavonoids as anti-inflammatory agents Proc. Nutr. Soc. 2010, 69, 273-278
28. Fernandez, M. A.; Saenz, M. T.; Garcia, M. D. Anti-inflammatory activity in rats and mice of phenolic acids isolated from Scrophularia frutescens J. Pharm. Pharmacol. 1998, 50, 1183-1186
29. Jones, L. H.; Abdalla, D. S.; Freitas, J. C. Effects of indole-3-acetic acid on croton oil-and arachidonic acid-induced mouse ear edema Inflammation Res. 1995, 44, 372-375