Ficolin-2 levels and genetic polymorphisms of FCN2 in malaria

Human Immunology

Volumn 72, Issue 1, 2011, Pages 74-79

  Faik, Imad ^a   Oyedeji, Segun I ^a   Idris, Zulkarnain ^a,b   de Messias Reason, Iara J ^a   Lell, Bertrand ^c   Kremsner, Peter G ^a,c   Kun, Jürgen F J ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b INSTITUTE FOR RESEARCH IN MOLECULAR MEDICINE INFORMM   (Malaysia)

^c ALBERT SCHWEITZER HOSPITAL   (Gabon)

Author keywords

FCN2 gene polymorphisms; Ficolin 2; Gabon; Malaria; Real time PCR

Indexed keywords

FICOLIN;

ADOLESCENT; ADULT; ALLELE; ARTICLE; BLOOD LEVEL; CHILD; CONTROLLED STUDY; DISEASE SEVERITY; EXON; FEMALE; GABON; GENE EXPRESSION; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC CODE; HAPLOTYPE; HOSPITAL ADMISSION; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALARIA; MALE; OUTCOME ASSESSMENT; PRESCHOOL CHILD; PRIORITY JOURNAL; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; SCHOOL CHILD; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

CHILD; CHILD, PRESCHOOL; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; HAPLOTYPES; HUMANS; INFANT; LECTINS; LINKAGE DISEQUILIBRIUM; MALARIA; MALE; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC;

EID: 78650176476     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2010.10.003     Document Type: Article

References (32)

1. Sachs J., Malaney P. The economic and social burden of malaria. Nature 2002, 415:680-685.
2. Greenwood B.M., Marsh K., Snow R.W. Why do some African children develop severe malaria?. Parasitol Today 1991, 7:277-281.
3. Serjeant G.R. Sickle Cell Disease 1992, Oxford Medical Publishing Group, Oxford.
4. Mackinnon M.J., Mwangi T.W., Snow R.W., Marsh K., Williams T.N. Heritability of malaria in Africa. PLoS Med 2005, 2:e340.
5. Faik I., de Carvalho E.G., Kun J.F. Parasite-host interaction in malaria: Genetic clues and copy number variation. Genome Med 2009, 1:82.
6. Runza V.L., Schwaeble W., Mannel D.N. Ficolins: Novel pattern recognition molecules of the innate immune response. Immunobiology 2008, 213:297-306.
7. Matsushita M., Endo Y., Hamasaki N., Fujita T. Activation of the lectin complement pathway by ficolins. Int Immunopharmacol 2001, 1:359-363.
8. Garlatti V., Belloy N., Martin L., Lacroix M., Matsushita M., Endo Y., et al. Structural insights into the innate immune recognition specificities of L- and H-ficolins. EMBO J 2007, 26:623-633.
9. Matsushita M., Endo Y., Fujita T. Cutting edge: Complement-activating complex of ficolin and mannose-binding lectin-associated serine protease. J Immunol 2000, 164:2281-2284.
10. Lynch N.J., Roscher S., Hartung T., Morath S., Matsushita M., Maennel D.N., et al. L-ficolin specifically binds to lipoteichoic acid, a cell wall constituent of Gram-positive bacteria, and activates the lectin pathway of complement. J Immunol 2004, 172:1198-1202.
11. dos S Cestari I., Krarup A., Sim R.B., Inal J.M., Ramirez M.I. Role of early lectin pathway activation in the complement-mediated killing of Trypanosoma cruzi. Mol Immunol 2009, 47:426-437.
12. Jensen M.L., Honore C., Hummelshoj T., Hansen B.E., Madsen H.O., Garred P. Ficolin-2 recognizes DNA and participates in the clearance of dying host cells. Mol Immunol 2007, 44:856-865.
13. Endo Y., Sato Y., Matsushita M., Fujita T. Cloning and characterization of the human lectin P35 gene and its related gene. Genomics 1996, 36:515-521.
14. de Messias-Reason I.J., Schafranski M.D., Kremsner P.G., Kun J.F.J. FCN2 functional polymorphisms and the risk of rheumatic fever and rheumatic heart disease. Clin Exp Immunol 2009, 157:395-399.
15. Hummelshoj T., Munthe-Fog L., Madsen H.O., Garred P. Functional SNPs in the human ficolin (FCN) genes reveal distinct geographical patterns. Mol Immunol 2008, 45:2508-2520.
16. Munthe-Fog L., Hummelshoj T., Hansen B.E., Koch C., Madsen H.O., Skjodt K., Garred P. The impact of FCN2 polymorphisms and haplotypes on the ficolin-2 serum levels. Scand J Immunol 2007, 65:383-392.
17. Hummelshoj T., Munthe-Fog L., Madsen H.O., Fujita T., Matsushita M., Garred P. Polymorphisms in the FCN2 gene determine serum variation and function of ficolin-2. Hum Mol Genet 2005, 14:1651-1658.
18. Hummelshoj T., Thielens N.M., Madsen H.O., Arlaud G.J., Sim R.B., Garred P. Molecular organization of human ficolin-2. Mol Immunol 2007, 44:401-411.
19. Atkinson A.P., Cedzynski M., Szemraj J., St.Swierzko A., Bak-Romaniszyn L., Banasik M., et al. L-ficolin in children with recurrent respiratory infections. Clin Exp Immunol 2004, 138:517-520.
20. Cedzynski M., Atkinson A.P., St.Swierzko A., Macdonald S.L., Szala A., Zeman K., et al. L-ficolin (ficolin-2) insufficiency is associated with combined allergic and infectious respiratory disease in children. Mol Immunol 2009, 47:415-419.
21. de Messias-Reason I., Kremsner P.G., Kun J.F. Functional haplotypes that produce normal ficolin-2 levels protect against clinical leprosy. J Infect Dis 2009, 199:801-804.
22. Klabunde J., Uhlemann A.C., Tebo A.E., Kimmel J., Schwarz R.T., Kremsner P.G., Kun J.F. Recognition of Plasmodium falciparum proteins by mannan-binding lectin, a component of the human innate immune system. Parasitol Res 2002, 88:113-117.
23. Boldt A.B., Luty A., Grobusch M.P., Dietz K., Dzeing A., Kombila M., et al. Association of a new mannose-binding lectin variant with severe malaria in Gabonese children. Genes Immun 2006, 7:393-400.
24. Kalmbach Y., Boldt A.B., Fendel R., Mordmüller B., Kremsner P.G., Kun J.F. Increase in annexin V-positive B cells expressing LILRB1/ILT2/CD85j in malaria. Eur Cytokine Netw 2006, 17:175-180.
25. Kun J.F.J., Mordmüller B., Lell B., Lehman L.G., Luckner D., Kremsner P.G. Polymorphism in the promoter region of the inducible nitric oxide synthase gene and protection against malaria. Lancet 1998, 351:265-266.
26. Kubista M., Andrade J.M., Bengtsson M., Forootan A., Jonak J., Lind K., et al. The real-time polymerase chain reaction. Mol Aspects Med 2006, 27:95-125.
27. Livak K.J., Flood S.J., Marmaro J., Giusti W., Deetz K. Oligonucleotides with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization. PCR Methods Appl 1995, 4:357-362.
28. Kilpatrick D.C., Chalmers J.D., Macdonald S.L., Murray M., Mohammed A., Hart S.P., et al. Stable bronchiectasis is associated with low serum L-ficolin concentrations. Clin Respir J 2009, 3:29-33.
29. Luty A.J.F., Kun J.F.J., Kremsner P.G. Mannose-binding lectin plasma levels and gene polymorphisms in Plasmodium falciparum malaria. J Infect Dis 1998, 178:1221-1224.
30. Hviid L., Kurtzhals J.A., Goka B.Q., Oliver-Commey J.O., Nkrumah F.K., Theander T.G. Rapid reemergence of T cells into peripheral circulation following treatment of severe and uncomplicated Plasmodium falciparum malaria. Infect Immun 1997, 65:4090-4093.
31. Kalmbach Y., Boldt A.B., Mordmüller B., Kombila M., Grobusch M.P., Kremsner P.G., Kun J.F. Reduced CD3/TCR complex expression leads to immunosuppression during Plasmodium falciparum malaria. Parasitol Res 2009, 104:575-582.
32. Kemp K., Akanmori B.D., Adabayeri V., Goka B.Q., Kurtzhals J.A., Behr C., Hviid L. Cytokine production and apoptosis among T cells from patients under treatment for Plasmodium falciparum malaria. Clin Exp Immunol 2002, 127:151-157.