L-Ficolin Specifically Binds to Lipoteichoic Acid, a Cell Wall Constituent of Gram-Positive Bacteria, and Activates the Lectin Pathway of Complement

Journal of Immunology

Volumn 172, Issue 2, 2004, Pages 1198-1202

  Lynch, Nicholas J ^a   Roscher, Silke ^a   Hartung, Thomas ^b   Morath, Siegfried ^b   Matsushita, Misao ^c   Maennel, Daniela N ^d   Kuraya, Mikio ^e   Fujita, Teizo ^e   Schwaeble, Wilhelm J ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b UNIVERSITY OF KONSTANZ   (Germany)

^c TOKAI UNIVERSITY   (Japan)

^d UNIVERSITY OF REGENSBURG   (Germany)

^e FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE; COMPLEMENT; COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C4; H FICOLIN; L FICOLIN; LECTIN; LIPOTEICHOIC ACID; MANNAN BINDING LECTIN; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL CELL WALL; BLOOD LEVEL; COMPLEMENT ACTIVATION; COMPLEMENT CLASSICAL PATHWAY; COMPLEX FORMATION; CONTROLLED STUDY; GRAM POSITIVE BACTERIUM; HOST PATHOGEN INTERACTION; HOST RESISTANCE; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS; STREPTOCOCCUS AGALACTIAE; STREPTOCOCCUS PYOGENES;

EID: 1642495736     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.172.2.1198     Document Type: Article

References (30)

1. Ikeda, K., T. Sannoh, N. Kawasaki, T. Kawasaki, and I. Yamashina. 1987. Serum lectin with known structure activates complement through the classical pathway. J. Biol. Chem. 262:7451.
2. Matsushita, M., and T. Fujita. 1992. Activation of the classical complement pathway by mannose-binding protein in association with a novel C1s-like serine protease. J. Exp. Med. 176:1497.
3. Matsushita, M., Y. Endo, and T. Fujita. 2000. Cutting edge: complement-activating complex of ficolin and mannose-binding lectin-associated serine protease. J. Immunol. 164:2281.
4. Matsushita, M., M. Kuraya, N. Hamasaki, M. Tsujimura, H. Shiraki, and T. Fujita. 2002. Activation of the lectin complement pathway by H-ficolin (Hakata antigen). J. Immunol. 168:3502.
5. Matsushita, M., and T. Fujita. 2002. The role of ficolins in innate immunity. Immunobiology 205:490.
6. Takada, F., Y. Takayama, H. Hatsuse, and M. Kawakami. 1993. A new member of the C1s family of complement proteins found in a bactericidal factor. Rareactive factor, in human serum. Biochem. Biophys. Res. Commun. 196:1003.
7. Sato, T., Y. Endo, M. Matsushita, and T. Fujita. 1994. Molecular characterization of a novel serine protease involved in activation of the complement system by mannose-binding protein. Int. Immunol. 6:665.
8. Thiel, S., T. Vorup-Jensen, C. M. Stover, W. Schwaeble, S. B. Laursen, K. Poulsen, A. C. Willis, P. Eggleton, S. Hansen, U. Holmskov, et al. 1997. A second serine protease associated with mannan-binding lectin that activates complement. Nature 386:506.
9. Dahl, M. R., S. Thiel, M. Matsushita, T. Fujita, A. C. Willis, T. Christensen, T. Vorup-Jensen, and J. C. Jensenius. 2001. MASP-3 and its association with distinct complexes of the mannan-binding lectin complement activation pathway. Immunity 15:127.
10. Vorup-Jensen, T., S. V. Petersen, A. G. Hansen, K. Poulsen, W. Schwaeble, R. B. Sim, K. B. Reid, S. J. Davis, S. Thiel, and J. C. Jensenius. 2000. Distinct pathways of mannan-binding lectin (MBL)- and C1-complex autoactivation revealed by reconstitution of MBL with recombinant MBL-associated serine protease-2. J. Immunol. 165:2093.
11. Rossi, V., S. Cseh, I. Bally, N. M. Thielens, J. C. Jensenius, and G. J. Arlaud. 2002. Substrate specificities of recombinant mannan-binding lectin-associated serine proteases-1 and -2. J. Biol. Chem. 276:40880.
12. Schwaeble, W. J., Dahl, M. R., Thiel, S., Stover, C. M., and Jensenius, J. C. 2002. The mannan-binding lectin-associated serine proteases (MASPs) and MAp19: four components of the lectin pathway activation complex encoded by two genes. Immunobiology 205:455.
13. Neth, O., D. L. Jack, A. W. Dodds, H. Holzel, N. J. Klein, and M. W. Turner. 2000. Mannose-binding lectin binds to a range of clinically relevant microorganisms and promotes complement deposition. Infect. Immun. 68:688.
14. Jack, D. L., N. J. Klein, and M. W. Turner. 2001. Mannose-binding lectin: targeting the microbial world for complement attack and opsonophagocytosis. Immunol. Rev. 180:86.
15. Sugimoto, R., Y. Yae, M. Akaiwa, S. Kitajima, Y. Shibata, H. Sato, J. Hirata, K. Okochi, K. Izuhara, and N. Hamasaki. 1998. Cloning and characterization of the Hakata antigen a member of the ficolin/opsonin p35 lectin family. J. Biol. Chem. 273:20721.
16. Matsushita, M., Y. Endo, S. Taira, Y. Sato, T. Fujita, N. Ichikawa, M. Nakata, and T. Mizuochi. 1996. A novel human serum lectin with collagen- and fibrinogen-like domains that functions as an opsonin. J. Biol. Chem. 271:2448.
17. Morath, S., A. Stadelmaier, A. Geyer, R. R. Schmidt, and T. Hartung. 2002. Synthetic lipoteichoic acid from Staphylococcus aureus is a potent stimulus of cytokine release. J. Exp. Med. 195:1635.
18. Morath, S., A. Geyer, I. Spreitzer, C. Hermann, and T. Hartung. 2002. Structural decomposition and heterogeneity of commercial lipoteichoic acid preparation. Infect. Immun. 70:938.
19. Haurum, J. S., S. Thiel, H. P. Haagsman, S. B. Laursen, B. Larsen, and J. C. Jensenius. 1993. Studies on the carbohydrate-binding characteristics of human pulmonary surfactant-associated protein A and comparison with two other collectins: mannan-binding protein and conglutinin. Biochem J. 293:873.
20. Tsujimura, M., C. Ishida, Y. Sagara, T. Miyazaki, K. Murakami, H. Shiraki, K. Okochi, and Y. Maeda. 2001. Detection of serum thermolabile β2 macroglycoprotein (Hakata antigen) by enzyme-linked immunosorbent assay using polysaccharide produced by Aerococcus viridans. Clin Diagn. Lab. Immunol. 8:454.
21. Morath, S., A. Geyer, and T. Hartung. 2001. Structure-function relationship of cytokine induction by lipoteichoic acid from Staphylococcus aureus. J. Exp. Med. 193:393.
22. Petersen, S. V., S. Thiel, L. Jensen, R. Steffensen, and J. C. Jensenius. 2001. An assay for the mannan-binding lectin pathway of complement activation. J. Immunol. Methods 257:107.
23. Dodds, A. W. 1993. Small-scale preparation of complement components C3 and C4. Methods Enzymol. 223:46.
24. Le, Y., S. H. Lee, O. L. Kon, and J. Lu. 1998. Human L-ficolin: Plasma levels, sugar specificity, and assignment of its lectin activity to the fibrinogen-like (FBG) domain. FEBS Lett. 425:367.
25. Tauber, J. W., M. J. Polley, and J. B. Zabriskie. 1976. Nonspecific complement activation by streptococcal structures. II. Properdin-independent initiation of the alternate pathway. J. Exp. Med. 143:1352.
26. Wilkinson, B. J., Y. Kim, and P. K. Peterson. 1981. Factors affecting complement activation by Staphylococcus aureus cell walls, their components, and mutants altered in teichoid acid. Infect. Immun. 232:216.
27. Loos, M., F. Clas, and W. Fischer. 1986. Interaction of purified lipoteichoic acid with the classical complement pathway. Infect. Immun. 53:595.
28. Polotsky, V. Y., W. Fischer, R. A. Ezekowitz, and K. A. Joiner. 1996. Interactions of human mannose-binding protein with lipoteichoic acids. Infect. Immun. 64:380.
29. Neth, O., D. L. Jack, M. Johnson, N. J. Klein, and M. W. Turner. 2002. Enhancement of complement activation and opsonophagocytosis by complexes of mannose-binding lectin with mannose-binding lectin-associated serine protease after binding to Staphylococcus aureus. J. Immunol. 169:4430.
30. Fischer, W. 1987. 'Lipoteichoic acid' of Bifidobacterium bifidum subspecies pennsylvanicum DSM 20239: a lipoglycan with monoglycerohosphate side chains. Eur J. Biochem. 165:639.