The importance of molecular structures, endpoints' values, and predictivity parameters in QSAR research: QSAR analysis of a series of estrogen receptor binders

Molecular Diversity

Volumn 14, Issue 4, 2010, Pages 687-696

  Li, Jiazhong ^a,b   Gramatica, Paola ^a  

^a UNIVERSITY OF INSUBRIA   (Italy)

^b LANZHOU UNIVERSITY   (China)

Author keywords

Endocrine disruptors; Estrogen receptor binders; External validation parameters; Molecular conformation; Quantitative structure activity relationship (QSAR)

Indexed keywords

ENDOCRINE DISRUPTOR; ESTROGEN RECEPTOR;

ARTICLE; BIOASSAY; CHEMICAL STRUCTURE; CONFORMATION; CONTROLLED STUDY; ESTROGEN ACTIVITY; EXTERNAL VALIDITY; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REFERENCE DATABASE;

ANIMALS; COMPUTATIONAL BIOLOGY; DRUG EVALUATION, PRECLINICAL; ENDOCRINE DISRUPTORS; ENDPOINT DETERMINATION; FEMALE; FORECASTING; LIGANDS; MODELS, THEORETICAL; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; PROTEIN BINDING; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RATS; RECEPTORS, ESTROGEN; VALIDATION STUDIES AS TOPIC;

EID: 78650175254     PISSN: 13811991     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11030-009-9212-2     Document Type: Article

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