Solubility and partitioning of carbamazepine in a two-phase supercritical carbon dioxide/polyvinylpyrrolidone system

International Journal of Pharmaceutics

Volumn 403, Issue 1-2, 2011, Pages 96-100

  Ugaonkar, Shweta ^a   Needham, Thomas E ^a   Bothun, Geoffrey D ^b  

^a UNIVERSITY OF RHODE ISLAND   (United States)

^b University of Rhode Island   (United States)

Author keywords

Carbamazepine; Drug partitioning; Excipient; Formulation; Polymer swelling; Supercritical

Indexed keywords

CARBAMAZEPINE; CARBON DIOXIDE; DRUG CARRIER; PLASTICIZER; POVIDONE; SUPERCRITICAL CARBON DIOXIDE; UNCLASSIFIED DRUG;

ADSORPTION; ARTICLE; DRUG FORMULATION; DRUG SOLUBILITY; MOLECULAR WEIGHT; PHASE PARTITIONING; PRESSURE MEASUREMENT; PRIORITY JOURNAL; SURFACE PROPERTY; TEMPERATURE MEASUREMENT; ULTRAVIOLET SPECTROSCOPY;

ANTICONVULSANTS; CARBAMAZEPINE; CARBON DIOXIDE; CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; DRUG COMPOUNDING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MICROSCOPY, ELECTRON, SCANNING; MOLECULAR STRUCTURE; POVIDONE; SOLUBILITY; SOLUTIONS; SPECTROPHOTOMETRY, ULTRAVIOLET; SURFACE PROPERTIES;

EID: 78650171563     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.10.031     Document Type: Article

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