Synthesis of controlled-release products in supercritical medium

AIChE Journal

Volumn 48, Issue 4, 2002, Pages 856-866

  Guney, Ozge ^a   Akgerman, Aydin ^a  

^a Texas AandM University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADSORPTION; BIODEGRADATION; DIFFUSION; ISOTHERMS; ORGANIC SOLVENTS; SOLUBILITY; SYNTHESIS (CHEMICAL); TOXICITY;

RESIDUAL SOLVENTS;

DRUG PRODUCTS;

ANTINEOPLASTIC AGENT; CARBON DIOXIDE; ESTRADIOL; ESTROGEN; FLUOROURACIL; POLYGLACTIN; POLYMER;

MEDICAL APPLICATION;

ARTICLE; BIODEGRADABILITY; CANCER CHEMOTHERAPY; CONTROLLED DRUG RELEASE; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG SOLUBILITY; ESTROGEN THERAPY; MATHEMATICAL MODEL; PARTITION COEFFICIENT; SYNTHESIS;

EID: 0036557447     PISSN: 00011541     EISSN: None     Source Type: Journal    
DOI: 10.1002/aic.690480419     Document Type: Article

References (19)

1. Alessi, P., A. Cortesi, and I. Kikic, "Effect of Operating Parameters on the Impregnation of Polymers with Drugs," Proc. Meeting on Supercritical Fluids, Nice, France, p. 373 (1998).
2. Camera-Roda, G., and Sarti, G. C., "Mass Transport with Relaxation in Polymers," AIChE J., 36, 851 (1990).
3. Debenedetti, P. G., J. W. Tom, S.-D. Yeo, and G.-B. Lim, "Application of SCFs for the Production of Sustained Delivery Devices," J. Controlled Release, 24, 27 (1993).
4. Gibbs, W. W., "Pressure to Change: Supercritical Carbon Dioxide to Toughen Common Materials," Sci. Amer., 275, 40 (1996).
5. Guney, O., and A. Akgerman, "Solubilities of 5-Fluorouracil and βEstradiol in Supercritical Carbon Dioxide," J. Chem. Eng. Data, 45, 1049 (2000).
6. 2 Plasticization and Dye Impregnation," Appl. Spectros., 51, 491 (1997).
7. Kikic, I., and P. Sist, "Applications of Supercritical Fluids to Pharmaceuticals: Controlled Drug Release Systems," Proc. Int. NATO-ASI Meeting, Kemer, Turkey (1998).
8. Kumar, S. K., U. W. Suter, and R. C. Reid, "Fractionation of Polymers with Supercritical Fluids," Fluid Phase Equilibria, 29, 373 (1986).
9. Leong, K. W., and R. Langer, "Polymeric Controlled Drug Delivery," Adv. Drug Delivery Release, 1, 199 (1987).
10. McHugh, M. A., and V. J. Krukonis, Supercritical Fluid Extraction: Principles and Practice, Butterworths, Boston (1986).
11. Paulaitis, M. E., V. J. Krukonis, and R. C. Reid, "Supercritical Fluid Extraction," Rev. Chem. Eng., 1(2), 179 (1983).
12. Poliakoff, M., and S. Howdle, "Supercritical Chemistry: Synthesis with a Spanner," Chem. Br., 1, 118 (1995).
13. 2," Chem. Tech., 1, 12 (1998).
14. Sand, M. L., "Method for Impregnating a Thermoplastic Polymer," U.S. Patent No. 4, 598, 006, Hercules Incorporated, Wilmington, DE (1986).
15. Saus, W., D. Knittel, and E. Schollmeyer, "Dyeing of Textiles in Supercritical Carbon Dioxide," Text. Res. J., 63, 135 (1993).
16. Shieh, Y.-T., J.-H. Su, G. Manivannan, P. H. C. Lee, S. P. Sawan, and W. D. Spall, "Interaction of Supercritical Carbon Dioxide with Polymers: II. Amorphous Polymers," J. Appl. Polym. Sci., 59, 707 (1996).
17. Shim, J. J., and K. P. Johnston, "Adjustable Solute Distribution between Polymers and Supercritical Fluids," AIChE J., 35, 1097 (1989).
18. Shim, J. J., and K. P. Johnston, "Molecular Thermodynamics of Solute-Polymer-Supercritical Fluid Systems," AIChE J., 37, 607 (1991).
19. Taki, S., E. Badens, J. S. Pic, and G. Charbit, "Coprecipitation of a Weedkiller and a Biodegradable Polymer," Proc. Meeting on Supercritical Fluids, Antibes, France (2000).