Inhibition of γ-secretase cleavage in the notch signaling pathway blocks HSV-2-induced type i and type II interferon production

Viral Immunology

Volumn 23, Issue 6, 2010, Pages 647-651

  Svensson, Alexandra ^a   Jäkärä, Emely ^a   Shestakov, Andrey ^a   Eriksson, Kristina ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GAMMA SECRETASE; GAMMA SECRETASE INHIBITOR; NOTCH RECEPTOR; PHYTOHEMAGGLUTININ;

ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; HERPES SIMPLEX VIRUS 2; HUMAN; HUMAN CELL; IMMUNE RESPONSE; NONHUMAN; PLASMACYTOID DENDRITIC CELL; PROTEIN FUNCTION;

AMYLOID PRECURSOR PROTEIN SECRETASES; BENZODIAZEPINONES; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; DENDRITIC CELLS; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; HERPES GENITALIS; HERPESVIRUS 2, HUMAN; HUMANS; INTERFERON TYPE I; INTERFERON-GAMMA; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

HUMAN HERPESVIRUS 2;

EID: 78650112610     PISSN: 08828245     EISSN: None     Source Type: Journal    
DOI: 10.1089/vim.2010.0013     Document Type: Article

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