19-base pair deletion polymorphism of the dihydrofolate reductase (DHFR) gene: Maternal risk of Down syndrome and folate metabolism;Polimorfismo de deleção de 19 pares de bases do gene dihidrofolato redutase (DHFR): Risco materno para síndrome de Down e metabolismo do folato

Sao Paulo Medical Journal

Volumn 128, Issue 4, 2010, Pages 215-218

  Mendes, Cristiani Cortez ^a   Biselli, Joice Matos ^a   Zampieri, Bruna Lancia ^a   Goloni Bertollo, Eny Maria ^a   Eberlin, Marcos Nogueira ^b   Haddad, Renato ^b   Riccio, Maria Francesca ^b   Vannucchi, Hélio ^c   Carvalho, Valdemir Melechco ^d   Pavarino Bertelli, Érika Cristina ^a  

^a FACULDADE DE MEDICINA DE SÃO JOSÉ DO RIO PRETO   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d Fleury   (Brazil)

Author keywords

Down syndrome; Folic acid; Genetic; Nondisjunction; Polymorphism; Risk factors

Indexed keywords

DIHYDROFOLATE REDUCTASE; FOLIC ACID; HOMOCYSTEINE; METHYLMALONIC ACID;

ADOLESCENT; ADULT; AGED; ARTICLE; BASE PAIRING; BRAZIL; CHEMOLUMINESCENCE; CHILD; CHROMOSOME 21; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DOWN SYNDROME; FEMALE; FOLATE METABOLISM; FOLIC ACID BLOOD LEVEL; GENE DELETION; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HUMAN; INTRON; LIQUID CHROMATOGRAPHY; MAJOR CLINICAL STUDY; MASS SPECTROMETRY; POLYMERASE CHAIN REACTION; PROTEIN BLOOD LEVEL; QUANTITATIVE ANALYSIS; RISK ASSESSMENT; SCHOOL CHILD;

EID: 78650076673     PISSN: 15163180     EISSN: None     Source Type: Journal    
DOI: 10.1590/s1516-31802010000400008     Document Type: Article

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