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Volumn 223, Issue 1, 2011, Pages 88-98

Nitrosative stress elicited by nNOSμ delocalization inhibits muscle force in dystrophin-null mice

Author keywords

sarcoglycan; Duchenne muscular dystrophy; dystrophin; mdx; mdx4cv; nitrosative stress; nitrotyrosination; nNOS; ryanodine receptor 1; S nitrosylation

Indexed keywords

CALCIUM; DELTA SARCOGLYCAN; DYSTROPHIN; NEURONAL NITRIC OXIDE SYNTHASE; NEURONAL NITRIC OXIDE SYNTHASE MU; REACTIVE NITROGEN SPECIES; UNCLASSIFIED DRUG;

EID: 78650021686     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2799     Document Type: Article
Times cited : (81)

References (69)
  • 1
    • 12344259558 scopus 로고    scopus 로고
    • 2004 William Allan Award address. Cloning of the DMD gene
    • Kunkel LM,. 2004 William Allan Award address. Cloning of the DMD gene. Am J Hum Genet 2005; 76: 205-214.
    • (2005) Am J Hum Genet , vol.76 , pp. 205-214
    • Kunkel, L.M.1
  • 2
    • 0027460658 scopus 로고
    • Dystrophin protects the sarcolemma from stresses developed during muscle contraction
    • Petrof BJ, Shrager JB, Stedman HH, et al., Dystrophin protects the sarcolemma from stresses developed during muscle contraction. Proc Natl Acad Sci U S A 1993; 90: 3710-3714.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 3710-3714
    • Petrof, B.J.1    Shrager, J.B.2    Stedman, H.H.3
  • 3
    • 0035891532 scopus 로고    scopus 로고
    • Role of nitric oxide in the pathogenesis of muscular dystrophies: A 'two hit' hypothesis of the cause of muscle necrosis
    • Rando TA,. Role of nitric oxide in the pathogenesis of muscular dystrophies: a 'two hit' hypothesis of the cause of muscle necrosis. Microsc Res Tech 2001; 55: 223-235.
    • (2001) Microsc Res Tech , vol.55 , pp. 223-235
    • Rando, T.A.1
  • 4
    • 65649111197 scopus 로고    scopus 로고
    • Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy
    • Lai Y, Thomas GD, Yue Y, et al., Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy. J Clin Invest 2009; 119: 624-635.
    • (2009) J Clin Invest , vol.119 , pp. 624-635
    • Lai, Y.1    Thomas, G.D.2    Yue, Y.3
  • 5
    • 0029149471 scopus 로고
    • Nitric oxide synthase complexed with dystrophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy
    • Brenman JE, Chao DS, Xia H, et al., Nitric oxide synthase complexed with dystrophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy. Cell 1995; 82: 743-752.
    • (1995) Cell , vol.82 , pp. 743-752
    • Brenman, J.E.1    Chao, D.S.2    Xia, H.3
  • 6
    • 0029835575 scopus 로고    scopus 로고
    • Selective loss of sarcolemmal nitric oxide synthase in Becker muscular dystrophy
    • Chao DS, Gorospe JR, Brenman JE, et al., Selective loss of sarcolemmal nitric oxide synthase in Becker muscular dystrophy. J Exp Med 1996; 184: 609-618.
    • (1996) J Exp Med , vol.184 , pp. 609-618
    • Chao, D.S.1    Gorospe, J.R.2    Brenman, J.E.3
  • 7
    • 8044254229 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase and dystrophin-deficient muscular dystrophy
    • Chang WJ, Iannaccone ST, Lau KS, et al., Neuronal nitric oxide synthase and dystrophin-deficient muscular dystrophy. Proc Natl Acad Sci U S A 1996; 93: 9142-9147.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 9142-9147
    • Chang, W.J.1    Iannaccone, S.T.2    Lau, K.S.3
  • 8
    • 0033593119 scopus 로고    scopus 로고
    • Alpha1-syntrophin gene disruption results in the absence of neuronal-type nitric-oxide synthase at the sarcolemma but does not induce muscle degeneration
    • Kameya S, Miyagoe Y, Nonaka I, et al., Alpha1-syntrophin gene disruption results in the absence of neuronal-type nitric-oxide synthase at the sarcolemma but does not induce muscle degeneration. J Biol Chem 1999; 274: 2193-2200.
    • (1999) J Biol Chem , vol.274 , pp. 2193-2200
    • Kameya, S.1    Miyagoe, Y.2    Nonaka, I.3
  • 9
    • 0031898432 scopus 로고    scopus 로고
    • Mdx muscle pathology is independent of nNOS perturbation
    • Crosbie RH, Straub V, Yun HY, et al., mdx muscle pathology is independent of nNOS perturbation. Hum Mol Genet 1998; 7: 823-829.
    • (1998) Hum Mol Genet , vol.7 , pp. 823-829
    • Crosbie, R.H.1    Straub, V.2    Yun, H.Y.3
  • 10
    • 0032411144 scopus 로고    scopus 로고
    • Impaired metabolic modulation of alpha-adrenergic vasoconstriction in dystrophin-deficient skeletal muscle
    • Thomas GD, Sander M, Lau KS, et al., Impaired metabolic modulation of alpha-adrenergic vasoconstriction in dystrophin-deficient skeletal muscle. Proc Natl Acad Sci U S A 1998; 95: 15090-15095.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 15090-15095
    • Thomas, G.D.1    Sander, M.2    Lau, K.S.3
  • 11
    • 7044223308 scopus 로고    scopus 로고
    • Absence of neuronal nitric oxide synthase (nNOS) as a pathological marker for the diagnosis of Becker muscular dystrophy with rod domain deletions
    • Torelli S, Brown SC, Jimenez-Mallebrera C, et al., Absence of neuronal nitric oxide synthase (nNOS) as a pathological marker for the diagnosis of Becker muscular dystrophy with rod domain deletions. Neuropathol Appl Neurobiol 2004; 30: 540-545.
    • (2004) Neuropathol Appl Neurobiol , vol.30 , pp. 540-545
    • Torelli, S.1    Brown, S.C.2    Jimenez-Mallebrera, C.3
  • 12
    • 0037211804 scopus 로고    scopus 로고
    • Relocalization of neuronal nitric oxide synthase (nNOS) as a marker for complete restoration of the dystrophin associated protein complex in skeletal muscle
    • Wells KE, Torelli S, Lu Q, et al., Relocalization of neuronal nitric oxide synthase (nNOS) as a marker for complete restoration of the dystrophin associated protein complex in skeletal muscle. Neuromuscul Disord 2003; 13: 21-31.
    • (2003) Neuromuscul Disord , vol.13 , pp. 21-31
    • Wells, K.E.1    Torelli, S.2    Lu, Q.3
  • 13
    • 0035139227 scopus 로고    scopus 로고
    • Physiology of nitric oxide in skeletal muscle
    • Stamler JS, Meissner G,. Physiology of nitric oxide in skeletal muscle. Physiol Rev 2001; 81: 209-237.
    • (2001) Physiol Rev , vol.81 , pp. 209-237
    • Stamler, J.S.1    Meissner, G.2
  • 14
    • 0035891533 scopus 로고    scopus 로고
    • Detection of reactive oxygen and reactive nitrogen species in skeletal muscle
    • Murrant CL, Reid MB,. Detection of reactive oxygen and reactive nitrogen species in skeletal muscle. Microsc Res Tech 2001; 55: 236-248.
    • (2001) Microsc Res Tech , vol.55 , pp. 236-248
    • Murrant, C.L.1    Reid, M.B.2
  • 15
    • 34147142547 scopus 로고    scopus 로고
    • The production of reactive oxygen and nitrogen species by skeletal muscle
    • Jackson MJ, Pye D, Palomero J,. The production of reactive oxygen and nitrogen species by skeletal muscle. J Appl Physiol 2007; 102: 1664-1670.
    • (2007) J Appl Physiol , vol.102 , pp. 1664-1670
    • Jackson, M.J.1    Pye, D.2    Palomero, J.3
  • 16
    • 0024580709 scopus 로고
    • Recovery of induced mutations for X chromosome-linked muscular dystrophy in mice
    • Chapman VM, Miller DR, Armstrong D, et al., Recovery of induced mutations for X chromosome-linked muscular dystrophy in mice. Proc Natl Acad Sci U S A 1989; 86: 1292-1296.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 1292-1296
    • Chapman, V.M.1    Miller, D.R.2    Armstrong, D.3
  • 17
    • 0027769462 scopus 로고
    • Targeted disruption of the neuronal nitric oxide synthase gene
    • Huang PL, Dawson TM, Bredt DS, et al., Targeted disruption of the neuronal nitric oxide synthase gene. Cell 1993; 75: 1273-1286.
    • (1993) Cell , vol.75 , pp. 1273-1286
    • Huang, P.L.1    Dawson, T.M.2    Bredt, D.S.3
  • 18
    • 0031755357 scopus 로고    scopus 로고
    • Muscular dystrophy in mdx mice despite lack of neuronal nitric oxide synthase
    • Chao DS, Silvagno F, Bredt DS,. Muscular dystrophy in mdx mice despite lack of neuronal nitric oxide synthase. J Neurochem 1998; 71: 784-789.
    • (1998) J Neurochem , vol.71 , pp. 784-789
    • Chao, D.S.1    Silvagno, F.2    Bredt, D.S.3
  • 19
    • 63149139634 scopus 로고    scopus 로고
    • Sub-physiological sarcoglycan expression contributes to compensatory muscle protection in mdx mice
    • Li D, Long C, Yue Y, et al., Sub-physiological sarcoglycan expression contributes to compensatory muscle protection in mdx mice. Hum Mol Genet 2009; 18: 1209-1220.
    • (2009) Hum Mol Genet , vol.18 , pp. 1209-1220
    • Li, D.1    Long, C.2    Yue, Y.3
  • 20
    • 0036127393 scopus 로고    scopus 로고
    • Modular flexibility of dystrophin: Implications for gene therapy of Duchenne muscular dystrophy
    • Harper SQ, Hauser MA, DelloRusso C, et al., Modular flexibility of dystrophin: implications for gene therapy of Duchenne muscular dystrophy. Nature Med 2002; 8: 253-261.
    • (2002) Nature Med , vol.8 , pp. 253-261
    • Harper, S.Q.1    Hauser, M.A.2    Dellorusso, C.3
  • 21
    • 0025815479 scopus 로고
    • Membrane organization of the dystrophin-glycoprotein complex
    • Ervasti JM, Campbell KP,. Membrane organization of the dystrophin-glycoprotein complex. Cell 1991; 66: 1121-1131.
    • (1991) Cell , vol.66 , pp. 1121-1131
    • Ervasti, J.M.1    Campbell, K.P.2
  • 22
    • 43449116927 scopus 로고    scopus 로고
    • Preservation of muscle force in mdx3cv mice correlates with low-level expression of a near full-length dystrophin protein
    • Li D, Yue Y, Duan D,. Preservation of muscle force in mdx3cv mice correlates with low-level expression of a near full-length dystrophin protein. Am J Pathol 2008; 172: 1332-1341.
    • (2008) Am J Pathol , vol.172 , pp. 1332-1341
    • Li, D.1    Yue, Y.2    Duan, D.3
  • 23
    • 0021137066 scopus 로고
    • Preparation and morphology of sarcoplasmic reticulum terminal cisternae from rabbit skeletal muscle
    • Saito A, Seiler S, Chu A, et al., Preparation and morphology of sarcoplasmic reticulum terminal cisternae from rabbit skeletal muscle. J Cell Biol 1984; 99: 875-885.
    • (1984) J Cell Biol , vol.99 , pp. 875-885
    • Saito, A.1    Seiler, S.2    Chu, A.3
  • 24
    • 67149105766 scopus 로고    scopus 로고
    • Proteomic analysis of S-nitrosylation and denitrosylation by resin-assisted capture
    • Forrester MT, Thompson JW, Foster MW, et al., Proteomic analysis of S-nitrosylation and denitrosylation by resin-assisted capture. Nature Biotechnol 2009; 27: 557-559.
    • (2009) Nature Biotechnol , vol.27 , pp. 557-559
    • Forrester, M.T.1    Thompson, J.W.2    Foster, M.W.3
  • 25
    • 12744269885 scopus 로고    scopus 로고
    • Adeno-associated virus-mediated microdystrophin expression protects young mdx muscle from contraction-induced injury
    • Liu M, Yue Y, Harper SQ, et al., Adeno-associated virus-mediated microdystrophin expression protects young mdx muscle from contraction-induced injury. Mol Ther 2005; 11: 245-256.
    • (2005) Mol Ther , vol.11 , pp. 245-256
    • Liu, M.1    Yue, Y.2    Harper, S.Q.3
  • 26
    • 0035726738 scopus 로고    scopus 로고
    • Tibialis anterior muscles in mdx mice are highly susceptible to contraction-induced injury
    • Dellorusso C, Crawford RW, Chamberlain JS, et al., Tibialis anterior muscles in mdx mice are highly susceptible to contraction-induced injury. J Muscle Res Cell Motil 2001; 22: 467-475.
    • (2001) J Muscle Res Cell Motil , vol.22 , pp. 467-475
    • Dellorusso, C.1    Crawford, R.W.2    Chamberlain, J.S.3
  • 27
    • 0001161283 scopus 로고
    • Density and composition of mammalian muscle
    • Mendez J, Keys A,. Density and composition of mammalian muscle. Metabolism 1960; 9: 184-188.
    • (1960) Metabolism , vol.9 , pp. 184-188
    • Mendez, J.1    Keys, A.2
  • 28
    • 0028485090 scopus 로고
    • Relationship between muscle fiber types and sizes and muscle architectural properties in the mouse hindlimb
    • Burkholder TJ, Fingado B, Baron S, et al., Relationship between muscle fiber types and sizes and muscle architectural properties in the mouse hindlimb. J Morphol 1994; 221: 177-190.
    • (1994) J Morphol , vol.221 , pp. 177-190
    • Burkholder, T.J.1    Fingado, B.2    Baron, S.3
  • 29
    • 0023753401 scopus 로고
    • Contractile properties of skeletal muscles from young, adult and aged mice
    • Brooks SV, Faulkner JA,. Contractile properties of skeletal muscles from young, adult and aged mice. J Physiol 1988; 404: 71-82.
    • (1988) J Physiol , vol.404 , pp. 71-82
    • Brooks, S.V.1    Faulkner, J.A.2
  • 30
    • 55949118714 scopus 로고    scopus 로고
    • Exercise-induced oxidative stress: Cellular mechanisms and impact on muscle force production
    • Powers SK, Jackson MJ,. Exercise-induced oxidative stress: cellular mechanisms and impact on muscle force production. Physiol Rev 2008; 88: 1243-1276.
    • (2008) Physiol Rev , vol.88 , pp. 1243-1276
    • Powers, S.K.1    Jackson, M.J.2
  • 31
    • 33645450207 scopus 로고    scopus 로고
    • Sarcolemmal damage in dystrophin deficiency is modulated by synergistic interactions between mechanical and oxidative/nitrosative stresses
    • Dudley RW, Danialou G, Govindaraju K, et al., Sarcolemmal damage in dystrophin deficiency is modulated by synergistic interactions between mechanical and oxidative/nitrosative stresses. Am J Pathol 2006; 168: 1276-1287.
    • (2006) Am J Pathol , vol.168 , pp. 1276-1287
    • Dudley, R.W.1    Danialou, G.2    Govindaraju, K.3
  • 32
    • 33748474816 scopus 로고    scopus 로고
    • Dynamic responses of the glutathione system to acute oxidative stress in dystrophic mouse (mdx) muscles
    • Dudley RW, Khairallah M, Mohammed S, et al., Dynamic responses of the glutathione system to acute oxidative stress in dystrophic mouse (mdx) muscles. Am J Physiol Regul Integr Comp Physiol 2006; 291: R704-R710.
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.291
    • Dudley, R.W.1    Khairallah, M.2    Mohammed, S.3
  • 33
    • 61949338001 scopus 로고    scopus 로고
    • Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle
    • Bellinger AM, Reiken S, Carlson C, et al., Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle. Nature Med 2009; 15: 325-330.
    • (2009) Nature Med , vol.15 , pp. 325-330
    • Bellinger, A.M.1    Reiken, S.2    Carlson, C.3
  • 34
    • 0032740245 scopus 로고    scopus 로고
    • Endogenous nitric oxide synthesis: Biological functions and pathophysiology
    • Bredt DS,. Endogenous nitric oxide synthesis: biological functions and pathophysiology. Free Radic Res 1999; 31: 577-596.
    • (1999) Free Radic Res , vol.31 , pp. 577-596
    • Bredt, D.S.1
  • 35
    • 77949770385 scopus 로고    scopus 로고
    • Golgi and sarcolemmal neuronal NOS differentially regulate contraction-induced fatigue and vasoconstriction in exercising mouse skeletal muscle
    • Percival JM, Anderson KN, Huang P, et al., Golgi and sarcolemmal neuronal NOS differentially regulate contraction-induced fatigue and vasoconstriction in exercising mouse skeletal muscle. J Clin Invest 2010; 120: 816-826.
    • (2010) J Clin Invest , vol.120 , pp. 816-826
    • Percival, J.M.1    Anderson, K.N.2    Huang, P.3
  • 36
    • 0032916127 scopus 로고    scopus 로고
    • Solution structure of the extended neuronal nitric oxide synthase PDZ domain complexed with an associated peptide
    • Tochio H, Zhang Q, Mandal P, et al., Solution structure of the extended neuronal nitric oxide synthase PDZ domain complexed with an associated peptide. Nature Struct Biol 1999; 6: 417-421.
    • (1999) Nature Struct Biol , vol.6 , pp. 417-421
    • Tochio, H.1    Zhang, Q.2    Mandal, P.3
  • 37
    • 0033617473 scopus 로고    scopus 로고
    • Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex
    • Hillier BJ, Christopherson KS, Prehoda KE, et al., Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex. Science 1999; 284: 812-815.
    • (1999) Science , vol.284 , pp. 812-815
    • Hillier, B.J.1    Christopherson, K.S.2    Prehoda, K.E.3
  • 38
    • 0034610326 scopus 로고    scopus 로고
    • Functional muscle ischemia in neuronal nitric oxide synthase-deficient skeletal muscle of children with Duchenne muscular dystrophy
    • Sander M, Chavoshan B, Harris SA, et al., Functional muscle ischemia in neuronal nitric oxide synthase-deficient skeletal muscle of children with Duchenne muscular dystrophy. Proc Natl Acad Sci U S A 2000; 97: 13818-13823.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 13818-13823
    • Sander, M.1    Chavoshan, B.2    Harris, S.A.3
  • 39
    • 54849414205 scopus 로고    scopus 로고
    • Functional deficits in nNOSmu-deficient skeletal muscle: Myopathy in nNOS knockout mice
    • Percival JM, Anderson KN, Gregorevic P, et al., Functional deficits in nNOSmu-deficient skeletal muscle: myopathy in nNOS knockout mice. PLoS ONE 2008; 3: e3387.
    • (2008) PLoS ONE , vol.3
    • Percival, J.M.1    Anderson, K.N.2    Gregorevic, P.3
  • 40
    • 57049122968 scopus 로고    scopus 로고
    • Sarcolemma-localized nNOS is required to maintain activity after mild exercise
    • Kobayashi YM, Rader EP, Crawford RW, et al., Sarcolemma-localized nNOS is required to maintain activity after mild exercise. Nature 2008; 456: 511-515.
    • (2008) Nature , vol.456 , pp. 511-515
    • Kobayashi, Y.M.1    Rader, E.P.2    Crawford, R.W.3
  • 41
    • 67849096124 scopus 로고    scopus 로고
    • Nitric oxide deficiency determines global chromatin changes in Duchenne muscular dystrophy
    • Colussi C, Gurtner A, Rosati J, et al., Nitric oxide deficiency determines global chromatin changes in Duchenne muscular dystrophy. FASEB J 2009; 23: 2131-2141.
    • (2009) FASEB J , vol.23 , pp. 2131-2141
    • Colussi, C.1    Gurtner, A.2    Rosati, J.3
  • 42
    • 58049221125 scopus 로고    scopus 로고
    • HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment
    • Colussi C, Mozzetta C, Gurtner A, et al., HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment. Proc Natl Acad Sci U S A 2008; 105: 19183-19187.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 19183-19187
    • Colussi, C.1    Mozzetta, C.2    Gurtner, A.3
  • 43
    • 71849084350 scopus 로고    scopus 로고
    • Nitric oxide and repair of skeletal muscle injury
    • Filippin LI, Moreira AJ, Marroni NP, et al., Nitric oxide and repair of skeletal muscle injury. Nitric Oxide 2009; 21: 157-163.
    • (2009) Nitric Oxide , vol.21 , pp. 157-163
    • Filippin, L.I.1    Moreira, A.J.2    Marroni, N.P.3
  • 44
    • 0034071559 scopus 로고    scopus 로고
    • A role for nitric oxide in muscle repair: Nitric oxide-mediated activation of muscle satellite cells
    • Anderson JE,. A role for nitric oxide in muscle repair: nitric oxide-mediated activation of muscle satellite cells. Mol Biol Cell 2000; 11: 1859-1874.
    • (2000) Mol Biol Cell , vol.11 , pp. 1859-1874
    • Anderson, J.E.1
  • 45
    • 33646234945 scopus 로고    scopus 로고
    • Persistent and improved functional gain in mdx dystrophic mice after treatment with L -arginine and deflazacort
    • Archer JD, Vargas CC, Anderson JE,. Persistent and improved functional gain in mdx dystrophic mice after treatment with L -arginine and deflazacort. FASEB J 2006; 20: 738-740.
    • (2006) FASEB J , vol.20 , pp. 738-740
    • Archer, J.D.1    Vargas, C.C.2    Anderson, J.E.3
  • 46
    • 44849127317 scopus 로고    scopus 로고
    • L -arginine decreases inflammation and modulates the nuclear factor-kappaB/matrix metalloproteinase cascade in mdx muscle fibers
    • Hnia K, Gayraud J, Hugon G, et al., L -arginine decreases inflammation and modulates the nuclear factor-kappaB/matrix metalloproteinase cascade in mdx muscle fibers. Am J Pathol 2008; 172: 1509-1519.
    • (2008) Am J Pathol , vol.172 , pp. 1509-1519
    • Hnia, K.1    Gayraud, J.2    Hugon, G.3
  • 47
    • 33846043968 scopus 로고    scopus 로고
    • Nitric oxide release combined with nonsteroidal antiinflammatory activity prevents muscular dystrophy pathology and enhances stem cell therapy
    • Brunelli S, Sciorati C, D'Antona G, et al., Nitric oxide release combined with nonsteroidal antiinflammatory activity prevents muscular dystrophy pathology and enhances stem cell therapy. Proc Natl Acad Sci U S A 2007; 104: 264-269.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 264-269
    • Brunelli, S.1    Sciorati, C.2    D'Antona, G.3
  • 48
    • 24044503385 scopus 로고    scopus 로고
    • L -arginine improves dystrophic phenotype in mdx mice
    • Voisin V, Sebrie C, Matecki S, et al., L -arginine improves dystrophic phenotype in mdx mice. Neurobiol Dis 2005; 20: 123-130.
    • (2005) Neurobiol Dis , vol.20 , pp. 123-130
    • Voisin, V.1    Sebrie, C.2    Matecki, S.3
  • 49
    • 0035494438 scopus 로고    scopus 로고
    • A nitric oxide synthase transgene ameliorates muscular dystrophy in mdx mice
    • Wehling M, Spencer MJ, Tidball JG,. A nitric oxide synthase transgene ameliorates muscular dystrophy in mdx mice. J Cell Biol 2001; 155: 123-132.
    • (2001) J Cell Biol , vol.155 , pp. 123-132
    • Wehling, M.1    Spencer, M.J.2    Tidball, J.G.3
  • 50
    • 0028046502 scopus 로고
    • Nitric oxide in skeletal muscle
    • Kobzik L, Reid MB, Bredt DS, et al., Nitric oxide in skeletal muscle. Nature 1994; 372: 546-548.
    • (1994) Nature , vol.372 , pp. 546-548
    • Kobzik, L.1    Reid, M.B.2    Bredt, D.S.3
  • 51
    • 10744219879 scopus 로고    scopus 로고
    • Concerted regulation of skeletal muscle contractility by oxygen tension and endogenous nitric oxide
    • Eu JP, Hare JM, Hess DT, et al., Concerted regulation of skeletal muscle contractility by oxygen tension and endogenous nitric oxide. Proc Natl Acad Sci U S A 2003; 100: 15229-15234.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 15229-15234
    • Eu, J.P.1    Hare, J.M.2    Hess, D.T.3
  • 52
    • 38849094092 scopus 로고    scopus 로고
    • Stressed out: The skeletal muscle ryanodine receptor as a target of stress
    • Bellinger AM, Mongillo M, Marks AR,. Stressed out: the skeletal muscle ryanodine receptor as a target of stress. J Clin Invest 2008; 118: 445-453.
    • (2008) J Clin Invest , vol.118 , pp. 445-453
    • Bellinger, A.M.1    Mongillo, M.2    Marks, A.R.3
  • 53
    • 41149142599 scopus 로고    scopus 로고
    • RyR1 S-nitrosylation underlies environmental heat stroke and sudden death in Y522S RyR1 knockin mice
    • Durham WJ, Aracena-Parks P, Long C, et al., RyR1 S-nitrosylation underlies environmental heat stroke and sudden death in Y522S RyR1 knockin mice. Cell 2008; 133: 53-65.
    • (2008) Cell , vol.133 , pp. 53-65
    • Durham, W.J.1    Aracena-Parks, P.2    Long, C.3
  • 54
    • 41149180560 scopus 로고    scopus 로고
    • Remodeling of ryanodine receptor complex causes 'leaky' channels: A molecular mechanism for decreased exercise capacity
    • Bellinger AM, Reiken S, Dura M, et al., Remodeling of ryanodine receptor complex causes 'leaky' channels: a molecular mechanism for decreased exercise capacity. Proc Natl Acad Sci U S A 2008; 105: 2198-2202.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 2198-2202
    • Bellinger, A.M.1    Reiken, S.2    Dura, M.3
  • 55
    • 0035253580 scopus 로고    scopus 로고
    • Transgenic mice expressing mutant caveolin-3 show severe myopathy associated with increased nNOS activity
    • Sunada Y, Ohi H, Hase A, et al., Transgenic mice expressing mutant caveolin-3 show severe myopathy associated with increased nNOS activity. Hum Mol Genet 2001; 10: 173-178.
    • (2001) Hum Mol Genet , vol.10 , pp. 173-178
    • Sunada, Y.1    Ohi, H.2    Hase, A.3
  • 56
    • 77956546061 scopus 로고    scopus 로고
    • Arginine metabolism by macrophages promotes cardiac and muscle fibrosis in mdx muscular dystrophy
    • Wehling-Henricks M, Jordan MC, Gotoh T, et al., Arginine metabolism by macrophages promotes cardiac and muscle fibrosis in mdx muscular dystrophy. PLoS ONE 2010; 5: e10763.
    • (2010) PLoS ONE , vol.5
    • Wehling-Henricks, M.1    Jordan, M.C.2    Gotoh, T.3
  • 57
    • 0033885496 scopus 로고    scopus 로고
    • Differential requirement for individual sarcoglycans and dystrophin in the assembly and function of the dystrophin-glycoprotein complex
    • Hack AA, Lam MY, Cordier L, et al., Differential requirement for individual sarcoglycans and dystrophin in the assembly and function of the dystrophin-glycoprotein complex. J Cell Sci 2000; 113: 2535-2544.
    • (2000) J Cell Sci , vol.113 , pp. 2535-2544
    • Hack, A.A.1    Lam, M.Y.2    Cordier, L.3
  • 58
    • 0034886927 scopus 로고    scopus 로고
    • Stretch-activated cation channels in skeletal muscle myotubes from sarcoglycan-deficient hamsters
    • Nakamura TY, Iwata Y, Sampaolesi M, et al., Stretch-activated cation channels in skeletal muscle myotubes from sarcoglycan-deficient hamsters. Am J Physiol Cell Physiol 2001; 281: C690-C699.
    • (2001) Am J Physiol Cell Physiol , vol.281
    • Nakamura, T.Y.1    Iwata, Y.2    Sampaolesi, M.3
  • 59
    • 0035009498 scopus 로고    scopus 로고
    • Stretch-induced cell damage in sarcoglycan-deficient myotubes
    • Sampaolesi M, Yoshida T, Iwata Y, et al., Stretch-induced cell damage in sarcoglycan-deficient myotubes. Pflugers Arch 2001; 442: 161-170.
    • (2001) Pflugers Arch , vol.442 , pp. 161-170
    • Sampaolesi, M.1    Yoshida, T.2    Iwata, Y.3
  • 60
    • 23044431799 scopus 로고    scopus 로고
    • 2+ homeostasis and cell damage in myopathic skeletal muscle cells
    • 2+ homeostasis and cell damage in myopathic skeletal muscle cells. Biochem Pharmacol 2005; 70: 740-751.
    • (2005) Biochem Pharmacol , vol.70 , pp. 740-751
    • Iwata, Y.1    Katanosaka, Y.2    Shijun, Z.3
  • 62
    • 39749114099 scopus 로고    scopus 로고
    • Myostatin blockade improves function but not histopathology in a murine model of limb-girdle muscular dystrophy 2C
    • Bogdanovich S, McNally EM, Khurana TS,. Myostatin blockade improves function but not histopathology in a murine model of limb-girdle muscular dystrophy 2C. Muscle Nerve 2008; 37: 308-316.
    • (2008) Muscle Nerve , vol.37 , pp. 308-316
    • Bogdanovich, S.1    McNally, E.M.2    Khurana, T.S.3
  • 63
    • 0032849111 scopus 로고    scopus 로고
    • Muscle degeneration without mechanical injury in sarcoglycan deficiency
    • Hack AA, Cordier L, Shoturma DI, et al., Muscle degeneration without mechanical injury in sarcoglycan deficiency. Proc Natl Acad Sci U S A 1999; 96: 10723-10728.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 10723-10728
    • Hack, A.A.1    Cordier, L.2    Shoturma, D.I.3
  • 64
    • 38849097891 scopus 로고    scopus 로고
    • Calcium misregulation and the pathogenesis of muscular dystrophy
    • Hopf FW, Turner PR, Steinhardt RA,. Calcium misregulation and the pathogenesis of muscular dystrophy. Subcell Biochem 2007; 45: 429-464.
    • (2007) Subcell Biochem , vol.45 , pp. 429-464
    • Hopf, F.W.1    Turner, P.R.2    Steinhardt, R.A.3
  • 65
    • 0023739851 scopus 로고
    • Increased protein degradation results from elevated free calcium levels found in muscle from mdx mice
    • Turner PR, Westwood T, Regen CM, et al., Increased protein degradation results from elevated free calcium levels found in muscle from mdx mice. Nature 1988; 335: 735-738.
    • (1988) Nature , vol.335 , pp. 735-738
    • Turner, P.R.1    Westwood, T.2    Regen, C.M.3
  • 66
    • 1542299755 scopus 로고    scopus 로고
    • Mini-dystrophin restores L-type calcium currents in skeletal muscle of transgenic mdx mice
    • Friedrich O, Both M, Gillis JM, et al., Mini-dystrophin restores L-type calcium currents in skeletal muscle of transgenic mdx mice. J Physiol 2004; 555: 251-265.
    • (2004) J Physiol , vol.555 , pp. 251-265
    • Friedrich, O.1    Both, M.2    Gillis, J.M.3
  • 67
    • 2942724167 scopus 로고    scopus 로고
    • Improvement of calcium handling and changes in calcium-release properties after mini- or full-length dystrophin forced expression in cultured skeletal myotubes
    • Marchand E, Constantin B, Balghi H, et al., Improvement of calcium handling and changes in calcium-release properties after mini- or full-length dystrophin forced expression in cultured skeletal myotubes. Exp Cell Res 2004; 297: 363-379.
    • (2004) Exp Cell Res , vol.297 , pp. 363-379
    • Marchand, E.1    Constantin, B.2    Balghi, H.3
  • 69
    • 56149120851 scopus 로고    scopus 로고
    • Inhibitory control over Ca(2 +) sparks via mechanosensitive channels is disrupted in dystrophin deficient muscle but restored by mini-dystrophin expression
    • Teichmann MD, Wegner FV, Fink RH, et al., Inhibitory control over Ca(2 +) sparks via mechanosensitive channels is disrupted in dystrophin deficient muscle but restored by mini-dystrophin expression. PLoS ONE 2008; 3: e3644.
    • (2008) PLoS ONE , vol.3
    • Teichmann, M.D.1    Wegner, F.V.2    Fink, R.H.3


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