Nitration of the egg-allergen ovalbumin enhances protein allergenicity but reduces the risk for oral sensitization in a murine model of food allergy

PLoS ONE

Volumn 5, Issue 12, 2010, Pages

  Untersmayr, Eva ^a   Diesner, Susanne C ^a,b   Oostingh, Gertie Janneke ^c   Selzle, Kathrin ^d   Pfaller, Tobias ^c   Schultz, Cornelia ^a   Zhang, Yingyi ^d   Krishnamurthy, Durga ^a   Starkl, Philipp ^a   Knittelfelder, Regina ^a   Förster Waldl, Elisabeth ^b   Pollak, Arnold ^b   Scheiner, Otto ^a   Pöschl, Ulrich ^d   Jensen Jarolim, Erika ^a   Duschl, Albert ^c  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIV KLIN KINDER JUGENDHEILKUNDE   (Austria)

^c UNIVERSITY OF SALZBURG   (Austria)

^d MAX PLANCK INSTITUTE FOR CHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; ANTACID AGENT; EPITOPE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; OVALBUMIN; TYROSINE; IMMUNOGLOBULIN G; NITROGEN;

ALLERGENICITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; BAGG ALBINO MOUSE; CONTROLLED STUDY; DIGESTION; EGG; FEMALE; FOOD ALLERGY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNIZATION; IMMUNOGLOBULIN BLOOD LEVEL; MOUSE; NITRATION; NONHUMAN; PROTEIN STABILITY; RISK REDUCTION; SENSITIZATION; TANDEM MASS SPECTROMETRY; AIR POLLUTION; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; DISEASE MODEL; IMMUNOLOGY; INFLAMMATION; METHODOLOGY; MOLECULAR GENETICS; SMOG;

ANIMALIA; MURINAE; MUS;

AIR POLLUTION; ALLERGENS; AMINO ACID SEQUENCE; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DISEASE MODELS, ANIMAL; EPITOPES; FEMALE; FOOD HYPERSENSITIVITY; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; INFLAMMATION; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; NITROGEN; OVALBUMIN; SMOG; TANDEM MASS SPECTROMETRY; TYROSINE;

EID: 78649997938     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0014210     Document Type: Article

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