Whey peptides improve wound healing following caesarean section in rats

British Journal of Nutrition

Volumn 104, Issue 11, 2010, Pages 1621-1627

  Wang, Junbo ^a   Zhao, Ming ^a   Liang, Rui ^a   Zhang, Zhaofeng ^a   Zhao, Haifeng ^a   Zhang, Jiali ^a   Li, Tian ^a   Li, Yong ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Abdominal skin; Caesarean section; Rat uterus; Whey peptides; Wound healing

Indexed keywords

ALBUMIN; HYDROXYPROLINE; PEPTIDE; UNCLASSIFIED DRUG; WHEY PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CESAREAN SECTION; CONTROLLED STUDY; DIET THERAPY; FEMALE; HISTOPATHOLOGY; INTRAUTERINE PRESSURE; NEUTROPHIL COUNT; NONHUMAN; PROTEIN BLOOD LEVEL; PUERPERIUM; RAT; SKIN INCISION; SKIN SCAR; SURGICAL WOUND; TENSILE STRENGTH; TISSUE LEVEL; WOUND HEALING;

ALBUMINS; ANIMALS; CESAREAN SECTION; CICATRIX; DERMATOLOGIC AGENTS; FEMALE; HYDROXYPROLINE; MILK PROTEINS; NEUTROPHILS; PEPTIDES; PREGNANCY; PRESSURE; RATS; RATS, SPRAGUE-DAWLEY; SKIN; TENSILE STRENGTH; UTERUS; WOUND HEALING;

RATTUS;

EID: 78649982375     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114510002692     Document Type: Article

References (33)

1. Hamilton BE, Martin JA & Ventura SJ (2006) Births: Preliminary data for 2005. Natl Vital Stat Rep 55, 1-18.
2. Ofir K, Sheiner E, Levy A, et al. (2003) Uterine rupture: Risk factors and pregnancy outcome. Am J Obstet Gynecol 189, 1042-1046.
3. Locatelli A, Ghidini A, Ciriello E, et al. (2006) Induction of labor: Comparison of a cohort with uterine scar from previous cesarean section vs. a cohort with intact uterus. J Matern Fetal Neonatal Med 19, 471-475.
4. Caughey AB, Shipp TD, Repke JT, et al. (1999) Rate of uterine rupture during a trial of labor in women with one or two prior cesarean deliveries. Am J Obstet Gynecol 181, 872-876.
5. Thompson C & Fuhrman MP (2005) Nutrients and wound healing: Still searching for the magic bullet. Nutr Clin Pract 20, 331-347.
6. Oner OZ, Ogunc AV, Cingi A, et al. (2006) Whey feeding suppresses the measurement of oxidative stress in experimental burn injury. Surg Today 36, 376-381.
7. Ogunc AV, Manukyan M, Cingi A, et al. (2008) Dietary whey supplementation in experimental models of wound healing. Int J Vitam Nutr Res 78, 70-73.
8. Meisel H (2007) Food-derived bioactive proteins and peptides as potential components of nutraceuticals. Curr Pharm Des 13, 873-874.
9. Meisel H (2005) Biochemical properties of peptides encrypted in bovine milk proteins. Curr Med Chem 12, 1905-1919.
10. Peng X, Xiong YL & Kong B (2009) Antioxidant activity of peptide fractions from whey protein hydrolysates as measured by electron spin resonance. Food Chem 113, 196-201.
11. Bowers D, McKenzie D, Dutta D, et al. (2001) Growth hormone treatment after cesarean delivery in rats increases the strength of the uterine scar. Am J Obstet Gynecol 185, 614-617.
12. Reeves PG, Nielsen FH & Fahey GJ (1993) AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 123, 1939-1951.
13. Gul A, Kotan C, Ugras S, et al. (2001) Transverse uterine incision non-closure versus closure: An experimental study in dogs. Eur J Obstet Gynecol Reprod Biol 88, 95-99.
14. Eroglu E, Eroglu F, Agalar F, et al. (2001) The effect of lidocaine/ prilocaine cream on an experimental wound healing model. Eur J Emerg Med 8, 199-201.
15. Qiu Z, Kwon AH & Kamiyama Y (2007) Effects of plasma fibronectin on the healing of full-thickness skin wounds in streptozotocin-induced diabetic rats. J Surg Res 138, 64-70.
16. Wilgus TA, Vodovotz Y, Vittadini E, et al. (2003) Reduction of scar formation in full-thickness wounds with topical celecoxib treatment. Wound Repair Regen 11, 25-34.
17. Baum CL & Arpey CJ (2005) Normal cutaneous wound healing: Clinical correlation with cellular and molecular events. Dermatol Surg 31, 674-686.
18. Perez GR, Vargas SR & Ortiz HY (2005) Wound healing properties of Hylocereus undatus on diabetic rats. Phytother Res 19, 665-668.
19. Pettersson KW, Grunewald C & Thomassen P (2007) Uterine rupture and perinatal outcome. Acta Obstet Gyn Scan 86, 1337-1341.
20. Buhimschi CS, Buhimschi IA, Yu CL, et al. (2006) The effect of dystocia and previous cesarean uterine scar on the tensile properties of the lower uterine segment. Am J Obstet Gynecol 194, 873-883.
21. Pollio F, Staibano S, Mascolo M, et al. (2006) Uterine dehiscence in term pregnant patients with one previous cesarean delivery: Growth factor immunoexpression and collagen content in the scarred lower uterine segment. Am J Obstet Gynecol 194, 527-534.
22. Tsai JS, Chen TJ, Pan BS, et al. (2008) Antihypertensive effect of bioactive peptides produced by protease-facilitated lactic acid fermentation of milk. Food Chem 106, 552-558.
23. Feeser VR, Menke NB, Ward KR, et al. (2009) Androstenediol reverses steroid-inhibited wound healing. Wound Repair Regen 17, 758-761.
24. Reinhard G, Noll A, Schlebusch H, et al. (1998) Shifts in the TH1/TH2 balance during human pregnancy correlate with apoptotic changes. Biochem Biophys Res Commun 245, 933-938.
25. Kayser H & Meisel H (1996) Stimulation of human peripheral blood lymphocytes by bioactive peptides derived from bovine milk proteins. FEBS Lett 383, 18-20.
26. Eming SA, Hammerschmidt M, Krieg T, et al. (2009) Interrelation of immunity and tissue repair or regeneration. Semin Cell Dev Biol 20, 517-527.
27. Dissemond J, Goos M & Wagner SN (2002) The role of oxidative stress in the pathogenesis and therapy of chronic wounds. Hautarzt 53, 718-723.
28. Dovi JV, He LK & DiPietro LA (2003) Accelerated wound closure in neutrophil-depleted mice. J Leukoc Biol 73, 448-455.
29. Shukla A, Rasik AM & Patnaik GK (1997) Depletion of reduced glutathione, ascorbic acid, vitamin E and antioxidant defence enzymes in a healing cutaneous wound. Free Radic Res 26, 93-101.
30. Adamson B, Schwarz D, Klugston P, et al. (1996) Delayed repair: The role of glutathione in a rat incisional wound model. J Surg Res 62, 159-164.
31. Pathak N & Khandelwal S (2008) Impact of cadmium in T lymphocyte subsets and cytokine expression: Differential regulation by oxidative stress and apoptosis. Biometals 21, 179-187.
32. Shetty S, Udupa S & Udupa L (2008) Evaluation of antioxidant and wound healing effects of alcoholic and aqueous extract of Ocimum sanctum Linn in rats. Evid Based Complement Alternat Med 5, 95-101.
33. Gupta A, Upadhyay NK, Sawhney RC, et al. (2008) A poly-herbal formulation accelerates normal and impaired diabetic wound healing. Wound Repair Regen 16, 784-790.