A poly-herbal formulation accelerates normal and impaired diabetic wound healing

Wound Repair and Regeneration

Volumn 16, Issue 6, 2008, Pages 784-790

  Gupta, Asheesh ^a   Upadhyay, Nitin K ^a   Sawhney, R C ^a   Kumar, Ratan ^a  

^a DEFENCE INSTITUTE OF PHYSIOLOGY AND ALLIED SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALOE VERA EXTRACT; COLLAGEN; CURCUMA LONGA EXTRACT; DNA; HEXOSAMINE; HIPPOPHAE RHAMNOIDES EXTRACT; HYDROXYPROLINE; MATRIX METALLOPROTEINASE; POVIDONE IODINE; PROTEIN; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; CELL PROLIFERATION; CHORIOALLANTOIS; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DRUG EFFICACY; DRUG FORMULATION; GRANULATION TISSUE; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; OINTMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SKIN INJURY; STREPTOZOCIN DIABETES; TOPICAL TREATMENT; UPREGULATION; WOUND CONTRACTION; WOUND HEALING; WOUND HEALING IMPAIRMENT; ZYMOGRAPHY;

ALOE; ANIMALS; CURCUMA; DIABETES COMPLICATIONS; HIPPOPHAE; MALE; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; SKIN ULCER; TIME FACTORS; WOUND HEALING;

EID: 54949132506     PISSN: 10671927     EISSN: 1524475X     Source Type: Journal    
DOI: 10.1111/j.1524-475X.2008.00431.x     Document Type: Article

References (28)

1. Singer AJ, Clark RAF. Cutaneous wound healing. N Engl J Med 1999 341 : 738 46.
2. Komesu MC, Tanga MS, Buttrons KR, Nakao C. Effects of acute diabetes on rat cutaneous wound healing. Pathophysiol 2004 11 : 63 7.
3. Gupta A, Kumar R, Pal K, Banerjee PK, Sawhney RC. A preclinical study of the effects of Seabuckthorn (Hippophae rhamnoides L.) leaf extract on cutaneous wound healing in albino rats. Int J Low Ext Wounds 2005 4 : 88 92.
4. Reynolds T, Dweck AC. Aloe vera leaf gel: a review update. J Ethnopharmacology 1999 68 : 3 37.
5. Chitra P, Sajithlal GB, Chandrakasan G. Influence of Aloe vera on collagen characteristics in healing dermal wounds in rats. Mol Cellular Biochem 1998 181 : 71 6.
6. Ammon HP, Wahl MA. Pharmacology of Curcuma longa. Planta Med 1991 57 : 1 7.
7. Sidhu GS, Singh AK, Thaloor D, Banaudha KK, Paitnaik GK, Srimal RC, Maheshwari RK. Enhancement of wound healing by curcumin in animals. Wound Rep Regen 1998 6 : 167 77.
8. Panchatcharam M, Miriyala S, Gayathri VS, Suguna L. Curcumin improves wound healing by modulating collagen and decreasing reactive oxygen species. Mol Cellular Biochem 2006 290 : 87 96.
9. Singleton VL, Rossi JA. Calorimetry of total phenolics with phosphomolybdic phosphotungstic acid reagents. Am J Enol Vitic 1965 16 : 144 58.
10. Gupta A, Raghubir R. Energy metabolism in the granulation tissue of diabetic rats during cutaneous wound healing. Mol Cellular Biochem 2005 270 : 71 7.
11. Gupta A, Kumar R, Upadhyay NK, Pal K, Kumar R, Sawhney RC. Effects of Rhodiola imbricata on dermal wound healing. Planta Med 2007 73 : 774 7.
12. Woessner JF Jr. The determination of hydroxyproline in tissue and protein sample containing small proportions of this imino acid. Arch Biochem Biophys 1961 93 : 440 7.
13. Elson LA, Morgan WTJ. A colorimetric method for the determination of glucosamine and chondrosamine. Biochem J 1933 27 : 1824 8.
14. Burton K. A study of the condition and mechanism of the diphenylamine reaction for the calorimetric estimation of deoxyribonucleic acid. Biochem J 1956 62 : 315 21.
15. Lowry OH, Rosenburgh NJ, Farr AL, Randell BJ. Protein measurement with folin phenol reagent. J Biol Chem 1951 193 : 265 75.
16. Kumar MS, Sripriya R, Raghavan HV, Sehgal PK. Wound healing potential of Cassia fistula on infected albino rat model. J Surg Res 2006 131 : 283 9.
17. Harlow E, Lane D. Antibodies: a laboratory mannual. Cold Spring Harbor, NY : Cold Spring Harbor Labortory Press, 1988.
18. Lobb RR, Alderman EM, Fett JW. Induction of angiogenesis by bovine brain derived class I heparin binding growth factor. Biochemistry 1985 24 : 4970 3.
19. Niemisto A, Dunmire V, Yli-Harja O, Zhang W, Shmulevich I. Robust quantification of in-vitro angiogenesis through image analysis. IEEE Trans Med Imaging 2005 24 : 549 53.
20. Tripathi YB, Birendra KS, Pandey RS, Kumar M. BHUx: a patent polyherbal formulation to prevent atherosclerosis. eCAM 2005 2 : 217 21.
21. Kumar R, Shyam R, Diveker HM, Pahwa ML, Srivastava KK. Mechanism of increased tolerance to hypothermia after composite Indian herbal preparation II administration. J Alt Compl Med 2000 6 : 509 17.
22. Martin A, Komada MR, Sane DC. Abnormal angiogenesis in diabetes mellitus. Med Res Rev 2003 23 : 117 45.
23. Ferrara N. Molecular and biological properties of vascular endothelial growth factor. J Mol Med 1999 77 : 527 43.
24. Blakytny R, Jude E. The molecular biology of chronic wounds and delayed healing in diabetes. Diabetic Med 2006 2 : 594 608.
25. Moulin V, Auger FA, Garel D, German L. Role of wound healing myofibroblasts on re-epithelialization of human skin. Burns 2000 26 : 3 12.
26. Inkinen K, Turakainen R, Wolff H, Ravanti L, Kahari VM, Ahonen J. Expression and activity of matrix metalloproteinase-2 and -9 in experimental granulation tissue. APMIS 2000 5 : 318 28.
27. Marin A. The use of antioxidants in healing. Dermatol Surg 1996 22 : 156 60.
28. De-Groot H, Rauen U. Tissue injury by reactive oxygen species and the protective effects of flavonoides. Fundam Clin Pharmacol 1998 12 : 249 55.