Depletion of reduced glutathione, ascorbic acid, vitamin E and antioxidant defence enzymes in a healing cutaneous wound

Free Radical Research

Volumn 26, Issue 2, 1997, Pages 93-101

  Shukla, Arti ^a   Rasik, Anamika Mohan ^a   Patnaik, Gyanendra Kumar ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Antioxidants; Free radicals; Wound; Wound healing

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; CATALASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; MALONALDEHYDE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; LIPID PEROXIDATION; MALE; NONHUMAN; RAT; SKIN INJURY; WOUND HEALING;

ANIMALIA;

EID: 0030841973     PISSN: 10715762     EISSN: None     Source Type: Journal    
DOI: 10.3109/10715769709097788     Document Type: Article

References (25)

1. R. Ross and E. P. Bendit (1961). Wound healing and collagen formation. I. sequential changes in components of guinea pig skin wounds observed in electron microscope. Journal of Biophysical and Biochemical Cytology, 11, 665-677.
2. G. R. Grotendorst, D. Pencev, G. R. Martin and J. Sodek (1984). Soft and hard tissue repair (eds. T. K. Hunt, R. B. Heppenstall, E. Pines and D. Rovee) Praeger, New York, pp. 20-44.
3. G. G. Nemeth, M. E. Bolander and G. R. Martin (1987). Growth factors and their role in wound and fracture healing. Prognostic Clinical and Biological Research, 226, 1-3.
4. T. K. Hunt and Z. Hussain (1992). Wound healing: Biochemical and clinical aspects (ed. K. Cohen, R. F. Diegelmann and W. J. Lindblad) Saunders, Philadelphia, PA, pp. 274-281.
5. Y. Niwa, T. Kanoh, T. Sakane, H. Soh, S. Kawai and Y. Miyachi (1987). The ratio of lipid peroxides to Superoxide dismutase activity in skin lesions of patients with severe skin disease: An accurate prognostic indicator. Life Sciences, 40, 921-927.
6. S. Werner, M. Breeden, G. Hubner, D. G. Greenhalgh and M. T. Longaker (1994). Induction of keratinocyte growth factor expression is reduced and delayed during wound healing in the genetically diabetic mouse. Journal of Investigative Dermatology, 103, 469-473.
7. V. H. Cohn and J. Lyle (1966). A fluorometric assay for glutathione. Analytical Biochemistry, 14, 434-440.
8. J. H. Rae (1984). Chemical determination of ascorbic acid and diketogluconic acid. Methods of Biochemical Analysis (ed. Q. Gliek) vol. 1, pp. 115-139.
9. I. D. Desai (1984). Vitamin E analysis method for animal tissues, Methods of Enzymology (ed. E. Packer), vol 105, pp. 138-147.
10. P. Kakkar, B. Das and P. N. Viswanathan (1984). A modified spectro-photometric assay of Superoxide dismutase. Indian Journal of Biochemistry and Biophysics, 21, 130-132.
11. H. Aebi (1984). Catalase. In Methods of Enzymatic-Analysis (ed. H. U. Bergmeyer) Academic press, New York and London. vol. 2, pp. 673-684.
12. E. Beutler (1969). Effect of flavin compounds on glutathione reductase activity, in vivo and in vitro studies, Journal of Clinical Investigation, 48, 1957-1966.
13. L. Flohe and W. A. Gunzler (1984). Assay of glutathione peroxidase. Methods in Enzymology (ed. J. L. Packer) vol. 105, pp. 114-121.
14. W. H. Habig, M. J. Pabst and W. B. Jakoby (1974). Glutathione transferase. The first enzymatic step in mercapturic acid formation. Journal of Biological Chemistry, 249, 7130-7139.
15. O. H. Lowry, N. J. Rosebrough, A. L. Farr and R. J. Randall (1951). Protein measurement with the Folin-Phenol reagent. Journal of Biological Chemistry, 193, 265-275.
16. H. Ohkawa, N. Ohishi and K. Yogi (1979). Assay for lipid peroxides in animal tissue by thiobarbituric acid reaction. Analytical Biochemistry, 95, 351-358.
17. S. A. Silaeva, N. V. Guliaeva, B. I. Khatsernova, M. V. Onufriev and Ala. Nikolaev (1990). Effects of 4-methyluracil and carnosine on healing of skin wounds in rats. Blull-Eksp-Biology and Medicin, 109, 180-182.
18. G. S. Weinstein, M. D. Maves and M. L. McCormack (1989). Deferoxamine decreases necrosis in dorsally based pig skin flaps. Otolaryngol-Head-Neck-Surgery, 101, 559-561.
19. G. A. C. Murrell, M. J. O. Francis and L. Bromley (1990). Modulation of fibroblast proliferation by oxygen free radicals. Biochemical Journal, 265, 659-665.
20. H. Hemila, P. Roberts and M. Wikstrom (1984). Activated polymorphonuclear leucocytes consume vitamin C. Federation of European Biochemical Societies, 178, 25-30.
21. E. L. Thomas, D. B. Learn, M. Margaret and W. Weatherred (1988). Superoxide dependent oxidation of extracellular reducing agents by isolated neutrophils. Journal of Biological Chemistry, 263, 2178-2186.
22. G. A. Pascoe, M. W. Fariss, K. Olafsdottir and D. J. Reed (1987). The role of vitamin E in protection against cell injury. Maintenance of intracellular glutathione precursors and biosynthesis. European Journal of Biochemistry, 166, 241-247.
23. M. Chojkier, K. Houglum, J. S. Herruzo and D. A. Brenner (1989). Stimulation of collagen gene expression by ascorbic acid in cultured human fibroblasts. A role for lipid peroxidation? Journal of Biological Chemistry, 264, 16957-16962.
24. Y. Kiyohara, K. Nishiguchi, F. Komada, S. Iwakawa, M. Hirai and K. Okumura (1993). Cytoprotective effects of epidermal growth factor (EGF) ointment containing Nafamostat, a protease inhibitor, on tissue damage at burn sites in rats. Biological and Pharmacological Bulletin, 16, 1146-1149.
25. Y. Niwa, T. Kasama, S. Kawai, J. Komura, T. Sakane, T. Kanoh and Y. Miyachi (1988). The effect of aging on cutaneous lipid peroxide levels and Superoxide dismutase activity in guinea pigs and patients with burns. Life Sciences, 42, 351-356.