In vitro effects of cholesterol β-d-glucoside, cholesterol and cycad phytosterol glucosides on respiration and reactive oxygen species generation in brain mitochondria

Journal of Membrane Biology

Volumn 237, Issue 2-3, 2010, Pages 71-77

  Panov, Alexander ^a   Kubalik, Nataliya ^a   Brooks, Benjamin R ^a   Shaw, Christopher A ^b  

^a CAROLINAS MEDICAL CENTER   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Bioenergetics; Fatty acid binding through membranes; Membrane biology immunochemistry; Membrane biophysics

Indexed keywords

CHOLESTEROL; GLUCOSIDE; MEMBRANE LIPID; NEUROTOXIN; PHYTOSTEROL; REACTIVE OXYGEN METABOLITE; SITOSTEROL; SITOSTEROL DERIVATIVE; STIGMASTEROL GLUCOSIDE; SUCCINATE DEHYDROGENASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN MITOCHONDRION; CONCENTRATION (PARAMETERS); CYCADOPHYTA; ENZYME SUBSTRATE; HEART MITOCHONDRION; HELICOBACTER PYLORI; IN VITRO STUDY; MALE; MITOCHONDRIAL RESPIRATION; NERVE CELL; NERVE CELL LESION; NEUROTOXICITY; NONHUMAN; OXIDATION; OXIDATIVE STRESS; RAT; SYNAPSE;

ANIMALS; BRAIN; CELL RESPIRATION; CHOLESTEROL; DIMETHYL SULFOXIDE; GLUCOSIDES; HYDROGEN PEROXIDE; MITOCHONDRIA; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SITOSTEROLS; STIGMASTEROL;

CYCADOPSIDA; HELICOBACTER PYLORI;

EID: 78649960521     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00232-010-9307-9     Document Type: Article

References (31)

1. EM Bastiaanse KM Höld A van Der Laarse 1997 The effect of membrane cholesterol content on ion transport processes in plasma Cardiovasc Res 33 272 283 1:CAS:528:DyaK2sXhvVSmsLo%3D 10.1016/S0008-6363(96)00193-9 9074689 (Pubitemid 27072629)
2. MF Beal 2000 Energetics in the pathogenesis of neurodegenerative diseases Trends Neurosci 23 298 304 1:CAS:528:DC%2BD3cXktlCnu7g%3D 10.1016/S0166- 2236(00)01584-8 10856939 (Pubitemid 30387044)
3. AR Borenstein JA Mortimer E Schofield Y Wu DP Salmon A Gamst J Olichey LJ Thal L Silbert J Kaye UL Craig GD Schellenberg DR Glasko 2007 Cycad exposure and risk of dementia, MCI, and PDC in the Chamorro population of Guam Neurology 68 1764 1771 1:STN:280:DC%2BD2szgsVynsQ%3D%3D 10.1212/01.wnl.0000262027.31623.b2 17515538 (Pubitemid 46791389)
4. G Crémel D Filliol V Jancsik A Rendon 1990 Cholesterol distribution in rat liver and brain mitochondria as determined by stopped-flow kinetics with filipin Arch Biochem Biophys 278 142 147 10.1016/0003-9861(90) 90242-Q 2321954 (Pubitemid 20121885)
5. G Deliconstantinos L Kopeikina V Villiotou 1989 Evoked effects of cholesterol binding on integral proteins and lipid fluidity of dog brain synaptosomal plasma membranes Biochem Cell Biol 67 16 24 1:CAS:528: DyaL1MXhvVyisro%3D 10.1139/o89-003 2540777
6. EF Goodall KE Morrison 2006 Amyotrophic lateral sclerosis (motor neuron disease): proposed mechanisms and pathways to treatment Expert Rev Mol Med 8 1 22 10.1017/S1462399406010854 16723044
7. JT Greenamyre TB Sherer R Betarbet AV Panov 2001 Complex I and Parkinson's disease IUBMB Life 52 135 141 1:CAS:528:DC%2BD38Xlt1Wlsg%3D%3D 10.1080/15216540152845939 11798025
8. FL Hoch 1992 Cardiolipins and biomembrane function Biochim Biophys Acta 1113 71 133 1:CAS:528:DyaK38XhvV2lu7Y%3D 1550861
9. I Khabazian JS Bains DE Williams, et al. 2002 Isolation of various forms of sterol beta-d-glucoside from the seed of Cycas circinalis: neurotoxicity and implications for ALS-parkinsonism dementia complex J Neurochem 82 516 528 1:CAS:528:DC%2BD38Xmt1ejs7c%3D 10.1046/j.1471-4159.2002.00976.x 12153476 (Pubitemid 34831491)
10. L Kopeikina-Tsiboukidou G Deliconstantinos 1983 Functional changes of rat brain mitochondrial enzymes induced by monomeric cholesterol Int J Biochem 15 1403 1407 1:CAS:528:DyaL2cXjtFSisA%3D%3D 10.1016/0020-711X(83)90071-X 6317478 (Pubitemid 14200255)
11. S Kunimoto T Kobayashi S Kobayashi K Murakami-Murofushi 2000 Expression of cholesteryl glucoside by heat shock in human fibroblasts Cell Stress Chaperones 5 3 7 1:CAS:528:DC%2BD3cXhs12htbo%3D 10.1379/1466-1268(2000) 005<0003:EOCGBH>2.0.CO;2 10701833
12. S Kunimoto W Murofushi H Kai, et al. 2002 Steryl glucoside is a lipid mediator in stress-responsive signal transduction Cell Struct Funct 27 157 162 1:CAS:528:DC%2BD38Xns1aht78%3D 10.1247/csf.27.157 12207046
13. PTT Ly S Pelech CA Shaw 2008 Cholestryl glucoside stimulates activation of protein kinase B/Akt in motor neuron-derived NSC34 cell line Neurol Lipids 7 4
14. TD Madden C Vigo KR Bruckdorfer D Chapman 1980 The incorporation of cholesterol into inner mitochondrial membranes and its effect on lipid phase transition Biochim Biophys Acta 599 528 537 1:CAS:528:DyaL3cXlt1Omu74%3D 10.1016/0005-2736(80)90197-2 7407107
15. DC Mitchell BJ Litman 1998 Molecular order and dynamics in bilayers consisting of highly polyunsaturated phospholipids Biophys J 74 879 891 1:CAS:528:DyaK1cXhs1Kkurw%3D 10.1016/S0006-3495(98)74011-1 9533699
16. AV Panov RC Scaduto 1995 Influence of calcium on NADH and succinate oxidation by rat heart submitochondrial particles Arch Biochem Biophys 316 815 820 1:CAS:528:DyaK2MXjs1Kqu7s%3D 10.1006/abbi.1995.1109 7864638
17. A Panov L Andreeva JT Greenamyre 2004 Quantitative evaluation of the effects of mitochondrial permeability transition pore modifiers on accumulation of calcium phosphate: two modes of action of mPTP modifiers Arch Biochem Biophys 424 44 52 1:CAS:528:DC%2BD2cXhvFSls7o%3D 10.1016/j.abb.2004.01.013 15019835 (Pubitemid 38326853)
18. A Panov S Dikalov N Shalbuyeva R Hemendinger JT Greenamyre J Rosenfeld 2007 Species and tissue specific relationships between mitochondrial permeability transition and generation of ROS in brain and liver mitochondria of rats and mice Am J Physiol Cell Physiol 292 C708 C718 1:CAS:528: DC%2BD2sXjt1Gmtbg%3D 10.1152/ajpcell.00202.2006 17050617
19. A Panov P Schonfeld S Dikalov R Hemendinger HL Bonkovsky BR Brooks 2009 The neuromediator glutamate, through specific substrate interactions, enhances mitochondrial ATP production and reactive oxygen species generation in nonsynaptic brain mitochondria J Biol Chem 284 14448 14456 1:CAS:528: DC%2BD1MXlvV2isr0%3D 10.1074/jbc.M900985200 19304986
20. MS Petrik JMB Wilson SC Grant, et al. 2007 Magnetic resonance microscopy and immunohistochemistry of the CNS of the mutant SOD murine model of ALS reveals widespread neural deficits Neurol Med 9 216 229 1:CAS:528: DC%2BD2sXhtV2gt7jO 10.1007/s12017-007-8002-1 (Pubitemid 350129697)
21. FM Ruggiero F Cafagna V Petruzzella, et al. 1992 Lipid composition in synaptic and nonsynaptic mitochondria from rat brains and effect of aging J Neurochem 59 487 491 1:CAS:528:DyaK38Xlt1yksrk%3D 10.1111/j.1471-4159.1992. tb09396.x 1629722
22. H Schneider M Hochli CR Hackenbrock 1982 Relationship between the density distribution of intramembrane particles and electron transfer in the mitochondrial inner membrane as revealed by cholesterol incorporation J Cell Biol 94 387 393 1:CAS:528:DyaL38Xlt1ant7Y%3D 10.1083/jcb.94.2.387 7107704 (Pubitemid 12026788)
23. JD Schulz EL Hawkes CA Shaw 2006 Cycad toxins, Helicobacter pylori and parkinsonism: cholesterol glucosides as the common denominator Med Hypotheses 66 1222 1226 1:CAS:528:DC%2BD28XivFSisbo%3D 10.1016/j.mehy.2004.12.033 16488551
24. A Seelig PR Allegrini J Seelig 1988 Partitioning of local anesthetics into membranes: surface charge effects monitored by the phospholipid head-group Biochim Biophys Acta 939 267 276 1:CAS:528:DyaL1cXhvFyhtL0%3D 10.1016/0005-2736(88)90070-3 3355817 (Pubitemid 18089453)
25. NR Sims 1990 Rapid isolation of metabolically active mitochondria from rat brain and subregions using Percoll density gradient centrifugation J Neurochem 55 698 707 1:CAS:528:DyaK3cXltFWrt7c%3D 10.1111/j.1471-4159.1990. tb04189.x 2164576
26. LL Smith BH Johnson 1989 Biological activities of oxysterols Free Radic Biol Med 7 285 332 1:CAS:528:DyaK3MXksVChu7Y%3D 10.1016/0891-5849(89)90136-6 2673947 (Pubitemid 19234179)
27. RC Tabata JM Wilson P Ly, et al. 2008 Chronic exposure to dietary sterol glucosides is neurotoxic to motor neurons and induces an ALS-PDC phenotype Neuromol Med 10 24 39 1:CAS:528:DC%2BD1cXjt1eitLs%3D 10.1007/s12017-007-8020-z
28. T Tannaes HJ Grav G Bukholm 2000 Lipid profiles of Helicobacter pylori colony variants APMIS 108 349 356 1:CAS:528:DC%2BD3cXlvVakt70%3D 10.1034/j.1600-0463.2000.d01-67.x 10937772
29. GT Vatassery HT Quach WE Smith F Ungar 1997 Oxidation of cholesterol in synaptosomes and mitochondria isolated from rat brains Lipids 32 879 886 1:CAS:528:DyaK2sXls1Sksbo%3D 10.1007/s11745-997-0113-1 9270981 (Pubitemid 27360396)
30. MG Whiting 1963 Toxicity of cycads Econ Bot 17 271 302 1:CAS:528:DyaF2cXntFansA%3D%3D
31. JM Wilson I Khabazian MC Wong, et al. 2002 Behavioral and neurological correlates of ALS-parkinsonism dementia complex in adult mice fed washed cycad flour Neuromol Med 1 207 221 1:CAS:528:DC%2BD38XltVyhtL8%3D 10.1385/NMM:1:3:207 (Pubitemid 37012517)