The neuromediator glutamate, through specific substrate interactions, enhances mitochondrial ATP production and reactive oxygen species generation in nonsynaptic brain mitochondria

Journal of Biological Chemistry

Volumn 284, Issue 21, 2009, Pages 14448-14456

  Panov, Alexander ^a   Schonfeld, Peter ^b   Dikalov, Sergey ^c   Hemendinger, Richelle ^a   Bonkovsky, Herbert L ^a   Brooks, Benjamin Rix ^a  

^a CAROLINAS MEDICAL CENTER   (United States)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BOVINE SERUM ALBUMINS; BRAIN MITOCHONDRIA; ELECTRON TRANSPORT; NEURONAL ACTIVATION; OXIDATIVE PHOSPHORYLATION; PYRUVATE; REACTIVE OXYGEN SPECIES; SUBSTRATE INTERACTION; SYNAPTIC CLEFT; TRICARBOXYLIC ACID CYCLE;

BODY FLUIDS; ELECTRON TRANSITIONS; ELECTRON TRANSPORT PROPERTIES; MITOCHONDRIA; OXIDATION; OXYGEN; PHOSPHORYLATION;

SUBSTRATES;

ADENOSINE TRIPHOSPHATE; GLUTAMIC ACID; MALIC ACID; OXALOACETIC ACID; PYRUVIC ACID; REACTIVE OXYGEN METABOLITE; SUCCINATE DEHYDROGENASE (UBIQUINONE); SUCCINIC ACID; TRICARBOXYLIC ACID; BOVINE SERUM ALBUMIN; HYDROGEN PEROXIDE; SUCCINIC ACID DERIVATIVE;

ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; BRAIN SYNAPTOSOME; CELL ACTIVATION; CONTROLLED STUDY; ELECTRON TRANSPORT; ENERGY METABOLISM; ENERGY YIELD; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; HEART MITOCHONDRION; MALE; MITOCHONDRIAL RESPIRATION; NERVE CELL; NONHUMAN; OXIDATION; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; RAT; REVERSE ELECTRON TRANSPORT; ANIMAL; BIOLOGICAL MODEL; BIOSYNTHESIS; BRAIN; CELL RESPIRATION; DRUG EFFECT; METABOLISM; MITOCHONDRION; OXIDATION REDUCTION REACTION; SPRAGUE DAWLEY RAT; SYNAPSE;

BOVINAE;

ADENOSINE TRIPHOSPHATE; ANIMALS; BRAIN; CELL RESPIRATION; GLUTAMIC ACID; HYDROGEN PEROXIDE; MALE; MITOCHONDRIA; MITOCHONDRIA, HEART; MODELS, BIOLOGICAL; NEURONS; OXIDATION-REDUCTION; PYRUVIC ACID; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SERUM ALBUMIN, BOVINE; SUBSTRATE SPECIFICITY; SUCCINATES; SYNAPSES;

EID: 67649743314     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M900985200     Document Type: Article

References (54)

1. Greenamyre, J. T., Sherer, T. B., Betarbet, R., and Panov, A. V. (2001) IUBMB Life 52, 135-141
2. Martin, L. J., Liu, Z., Chen, K., Price, A. C., Pan, Y., Swaby, J. A., and Golden, W. C. (2007) J. Comp. Neurol. 500, 20-46
3. Kwong, J. Q., Beal, M. F., and Manfredi, G. (2006) J. Neurochem. 97, 1659-1675
4. Shaw, P. J. (2005) J. Neurol. Neurosurg. Psychiatry 76, 1046-1057
5. Erecinska, M., and Nelson, D. (1994) J. Neurochem. 63, 1033-1041
6. Halliwell, B. (2006) J. Neurochem. 97, 1634-1658
7. Bohr, V. A., Ottersen, O. P., and Tonjum, T. (2007) Neuroscience 145, 1183-1186
8. Kudin, A. P., Malinska, D., and Kunz, W. S. (2008) Biochim. Biophys. Acta 1777, 689-695
9. Schagger, H., and Pfeiffer, K. (2001) J. Biol. Chem. 276, 37861-37867
10. Panov, A., Dikalov, S., Shalbuyeva, N., Hemendinger, R., Greenamyre, J. T., and Rosenfeld, J. (2007) Am. J. Physiol. 292, C708-C718
11. Attwell, D., and Laughlin, S. B. (2001) J. Cereb. Blood Flow Metab. 21, 1133-1145
12. Pellerin, L., and Magistretti, P. J. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 10625-10629
13. Hertz, L., Peng, L., and Dienel, G. A. (2007) J. Cereb. Blood Flow Metab. 27, 219-249
14. Berkich, D. A., Ola, M. S., Cole, J., Sweatt, A. J., Hutson, S. M., and LaNoue, K. F. (2007) J. Neurosci. Res. 85, 3367-3677
15. McKenna, M. C., Waagepetersen, H. S., Schousboe, A., and Sonnewald, U. (2006) Biochem. Pharmacol. 71, 399-407
16. LaNoue, K. F., and Schoolwerth, A. C. (1979) Annu. Rev. Biochem. 48, 871-922
17. Hertz, L. (2004) Neurochem. Int. 45, 285-296
18. Yudkoff, M., Nelson, D., Daikhin, Y., and Erecinska, M. (1994) J. Biol. Chem. 269, 27414-27420
19. Kauppinen, R. A., and Nicholls, D. G. (1986) Eur. J. Biochem. 158, 159-165.
20. Rothstein, J. D., Martin, L., Levey, A. I., Dykes-Hoberg, M., Jin, L., Wu, D., Nash, N., and Kuncl, R. W. (1994) Neuron 13, 713-725
21. Danbolt, N. C. (2001) Prog. Neurobiol. 65, 1-105
22. Mim, C., Balani, P., Rauen, T., and Grewer, C. (2005) J. Gen. Physiol. 126, 571-589
23. Torres-Salazar, D., and Fahlke, C. (2007) J. Biol. Chem. 282, 34719-34726
24. Furness, D. N., Dehnes, Y., Akhtar, A. Q., Rossi, D. J., Hamann, M., Grutle, N. J., Gundersen, V., Holmseth, S., Lehre, K. P., Ullensvang, K., Wojewodzic, M., Zhou, Y., Attwell, D., and Danbolt, N. C. (2008) Neuroscience 157, 80-94
25. Dehnes, Y., Chaudhry, F. A., Ullensvang, K., Lehre, K. P., Storm-Mathisen, J., and Danbolt, N. C. (1998) J. Neurosci. 18, 3606-3619
26. Kanai, Y., Smith, C. P., and Hediger, M. A. (1993) FASEB J. 7, 1450-1459
27. Otis, T. S., Kavanaugh, M. P., and Jahr, C. E. (1997) Science 277, 1515-1518
28. Brasnjo, G., and Otis, T. S. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 6273-6278
29. Auger, C., and Attwell, D. (2000) Neuron 28, 547-558
30. Massie, A., Cnops, L., Smolders, I., McCullumsmith, R., Kooijman, R., Kwak, S., Arckens, L., and Michotte, Y. (2008) J. Comp. Neurol. 511, 155-172
31. Li, Z., Okamoto, K., Hayashi, Y., and Sheng, M. (2004) Cell 119, 873-887
32. Nicholls, D. G. (1993) Eur. J. Biochem. 212, 613-631
33. Abeles, M. (1991) Corticonics: Neural Circuits of the Cerebral Cortex, Cambridge University Press, Cambridge, UK
34. Tillakaratne, N. J., Medina-Kauwe, L., and Gibson, K. M. (1995) Comp. Biochem. Physiol. A 112, 247-263
35. Panov, A., Dikalov, S., and Rosenfeld, J. (2006) Free Radic. Biol. Med. 41, S167
36. Panov, A., Kubalik, N., Hemendinger, R., and Brooks, B. R. (2008) Amyotr. Lat. Scler. 9, S2-S3
37. Sims, N. R. (1990) J. Neurochem. 55, 698-707
38. Panov, A., Dikalov, S., Shalbueva, N., Taylor, G., Sherer, T., and Greenamyer, J. T. (2005) J. Biol. Chem. 280, 42026-42035
39. Tretter, L., Mayer-Takacs, D., and Adam-Vizi, V. (2007) Neurochem. Int. 50, 139-147
40. Bergles, D. E., Diamond, J. S., and Jahr, C. E. (1999) Curr. Opin. Neurobiol. 9, 293-298
41. McKenna, M. C., Stevenson, J. H., Huang, X., and Hopkins, I. B. (2000) Neurochem. Int. 37, 229-241
42. Ruscak, M., Orlicky, J., Zubor, V., and Hager, H. (1982) J. Neurochem. 39, 210-216
43. Cho, S. W., Lee, J., and Choi, S. Y. (1995) Eur. J. Biochem. 233, 340-346
44. Lai, J. C., Walsh, J. M., Dennis, S. C., and Clark, J. B. (1977) J. Neurochem. 28, 625-631
45. Cooper, A. J. L., and Plum, F. (1987) Physiol. Rev. 67, 440-519
46. McCormack, J. G., and Denton, R. M. (1979) Biochem. J. 180, 533-544
47. Panov, A., and Scarpa, A. (1996) Biochemistry 35, 427-432
48. Balazs, R. (1965) J. Neurochem. 12, 63-76
49. Balazs, R. (1965) Biochem. J. 95, 497-508
50. Ackrell, B. A., Kearney, E. B., and Edmondson, D. (1975) J. Biol. Chem. 250, 7114-7119
51. Vinogradov, A. D., Winter, D., and King, T. E. (1972) Biochem. Biophys. Res. Commun. 49, 441-444
52. Ackrell, B. A. C., Kearney, E. B., and Mayr, M. (1974) J. Biol. Chem. 249, 2021-2027
53. Zoccarato, D., Cavallini, L., Bortolami, S., and Alexandre, A. (2007) Biochem. J. 406, 125-129
54. Muller, F. L., Liu, Y., Abdul-Ghani, M. A., Lustgarten, M. S., Bhattacharya, A., Jang, Y. C., and Van Remmen, H. (2008) Biochem. J. 409, 491-499