Isochaihulactone protects PC12 cell against H2O2 induced oxidative stress and exerts the potent anti-aging effects in D-galactose aging mouse model

Acta Pharmacologica Sinica

Volumn 31, Issue 12, 2010, Pages 1532-1540

  Yu, Sung Liang ^a   Lin, Shih Bin ^b   Yu, Yung Luen ^c   Chien, Min Hui ^b   Su, Kuo Jung ^b   Lin, Ching Ju ^b   Way, Tzong Der ^d   Yiang, Giou Teng ^e   Lin, Chai Ching ^b   Chan, De Chuan ^f   Harn, Horng Jyh ^d   Chen, Yi Lin Sophia ^b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL ILAN UNIVERSITY   (Taiwan)

^c CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

^e TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^f TRI SERVICE GENERAL HOSPITAL   (Taiwan)

Author keywords

aging; anti aging; cyclooxygenase 2; D galactose; isochaihulactone; lignan; neuroprotection; PC12 cells

Indexed keywords

ALPHA TOCOPHEROL; COMPLEMENTARY DNA; CYCLOOXYGENASE 2; GALACTOSE; GLUTATHIONE PEROXIDASE; HERBACEOUS AGENT; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ISOCHAIHULACTONE; K8; LACTATE DEHYDROGENASE; LIGNAN; MALONALDEHYDE; NERVE GROWTH FACTOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; REACTIVE OXYGEN METABOLITE; RNA; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; BUPLEURUM SCORZONERIFOLIUM; CELL DEATH; CELL VIABILITY; CHEMICAL STRUCTURE; CHINESE MEDICINE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME ASSAY; FLUORESCENCE MICROSCOPY; HERB; HIPPOCAMPUS; LIPID PEROXIDATION; MALE; MEDICINAL PLANT; MOUSE; NERVE CELL; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING;

4-BUTYROLACTONE; ADENOSINE DIPHOSPHATE RIBOSE; AGING, PREMATURE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; BENZODIOXOLES; BUPLEURUM; CELL LINE, TUMOR; CELL SURVIVAL; CYCLOOXYGENASE 2; GALACTOSE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; MICE; MICE, INBRED C57BL; NF-KAPPA B; OXIDATIVE STRESS; PC12 CELLS; RATS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

EID: 78649927271     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2010.152     Document Type: Article

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