Immunosuppressive flavones and lignans from Bupleurum scorzonerifolium

Phytochemistry

Volumn 64, Issue 8, 2003, Pages 1375-1379

  Chang, Wen Liang ^a   Chiu, Li Wen ^a   Lai, Jenn Haung ^b   Lin, Hang Ching ^a  

^a NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^b TRI SERVICE GENERAL HOSPITAL   (Taiwan)

Author keywords

Bupleurum scorzonerifolium; Chaihunaphthone; Flavones; Immunosuppressive effect; Isochaihulactone; Lignans; Umbelliferae

Indexed keywords

BUPLEURUM ROOT; CD28 ANTIGEN; CHAIHUNAPHTHONE; EUGENIN; FLAVONE DERIVATIVE; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 2; ISOCHAIHULACTONE; KAEROPHYLLIN; LIGNAN; NEMEROSIN; OROXYLIN; SAIKOCHROMONE; UNCLASSIFIED DRUG; WOGONIN;

ARTICLE; BUPLEURUM SCORZONERIFOLIUM; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG CYTOTOXICITY; DRUG INHIBITION; DRUG ISOLATION; DRUG POTENCY; DRUG SCREENING; HUMAN; HUMAN CELL; MEDICINAL PLANT; PROTEIN SYNTHESIS INHIBITION; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS; T LYMPHOCYTE ACTIVATION;

APIACEAE; BUPLEURUM; BUPLEURUM SCORZONERIFOLIUM;

EID: 0345304862     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phytochem.2003.08.002     Document Type: Article

References (19)

1. Ali, A.A., Mahboul, M.A., Attia, A.A., Ali, A.T., 1990. Chromones and flavans from Pancratium maritimum. Phytochemistry 29, 625-627.
2. Badheka, L.P., Prabhu, B.R., Mulchandani, N.B., 1986. Dibenzybutyrolactone lignans from Piper cubeba. Phytochemistry 25, 487-489.
3. 13C NMR and molecular mechanics study. Magn. Reson. Chem. 29, 569-575.
4. Buschi, C.A., Pomilio, A.B., Gros, E.G., 1981. 5, 6, 7-Trisubstituted flavones from Gomphren amartiana. Phytochemistry 20, 1178-1179.
5. Chang, H.M., But, P.P.H., 1987. Pharmacology and Applications of Chinese Materia Medica. Vol. 2. World Scientific Publishing Co, Singapore.
6. Feliciano, A.S., Medarde, M., Lopez, J.L., Puebla, P., Corral, J.M., Barrero, A.F., 1989. Lignans from Juniperus thurifera. Phytochemistry 28, 2863-2866.
7. Gonzalez, A.G., Estevez-Reyes, R., Mato, C., Estevez-Braun, A.M., 1990. Isokaerophyllin, a butyrolactone from Bupleurum salicifolium. Phytochemistry 29, 675-678.
8. Harrison, L.J., Sia, G.L., Sim, K.Y., 1994. 5,7-Dihydroxy-8-methoxyflavone from Teraera indica. Planta Medica 60, 493-494.
9. Harrowven, D.C., 1993. A concise entry to the podophyllins. Tetrahedron 49, 9039-9048.
10. Ikeya, Y., Sugama, K., Okada, M., Mitsuhashi, H., 1991. Two xanthones from Polygala tenuifolia. Phytochemistry 30, 2061-2065.
11. Ito, H., Taniguchi, H., Kita, T., Natsuki, Y., Tachikawa, E., Fujita, T., 1977. Xanthones anda cinnamic acid derivatives from Polygala tenuifolia. Phytochemistry 16, 1614-1616.
12. Iwasaki, T., Kondo, K., Nishitani, T., Kuroda, T., Hirakoso, K., Ohtani, A., Takashima, K., 1995. Arylnaphthalene lignans as novel series of hypolipidemic agents raising high-density lipoprotein level. Chem. Pharm. Bull. 43, 1701-1705
13. Joshi, K.C., Singh, P., Singhi, C.L., 1983. Chemical constituents of Verbesina encelioides and Holmakioldia sanguinea. J. Indian Chem. Soc. 60, 905-906.
14. Klemm, L.H., Gopinath, K.W., Lee, D.H., Kelly, F.W., Trod, E., McGuire, T.M., 1966. The intramolecular Diels-Alder reaction as a route to synthetic lignan lactones. Tetrahedron 22, 1797-1808.
15. 18 fatty acid, a lignan and a new chromone. Chem. Pharm. Bull. 38, 3169-3171.
16. Lai, J.H., Ho, L.J., Kwan, C.Y., Chang, D.M., Lee, T.C., 1999. Plant alkaloid tetrandrine and its analog block CD28-costimulated activities of human peripheral blood T cells. Transplantation 68, 1383-1392.
17. Mikaya, G.A., Turabelidze, D.G., Kemertelide, E.P., Wulson, N.S., 1981. Kaerophyllin, a new lignan from Chaerophyllium maculatum. Planta Medica 43, 378-380.
18. Tomimori, T., Miyaichi, Y., Kizu, H., 1982. On the flavonoid constituents from the root of Scutellaria baicalensis. Yakugaku Zasshi 102, 388-391.
19. Tsui, W.Y., Brown, G.D., 1996. Chromone and chromanones from Baeckea frutescens. Phytochemistry 43, 871-876.