메뉴 건너뛰기




Volumn 7, Issue 12, 2010, Pages 1433-1446

Vaxfectin: A versatile adjuvant for plasmid DNA- and protein-based vaccines

Author keywords

adjuvant; cationic lipid; plasmid DNA; vaccine

Indexed keywords

APEX; IMMUNOLOGICAL ADJUVANT; INFLUENZA VACCINE; INTERLEUKIN 6; LIPOSOME; ONCEPT; PEPTIDE VACCINE; PLASMID DNA; UNCLASSIFIED DRUG; VAXFECTIN;

EID: 78649924914     PISSN: 17425247     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425247.2010.538047     Document Type: Review
Times cited : (52)

References (41)
  • 1
    • 0026579897 scopus 로고
    • Genetic immunization is a simple method for eliciting an immune response
    • Tang D-C, DeVit M, Rouse BT. Genetic immunization is a simple method for eliciting an immune response. Nature 1992;356:152-54
    • (1992) Nature , vol.356 , pp. 152-154
    • Tang, D.-C.1    DeVit, M.2    Rouse, B.T.3
  • 2
    • 0027411456 scopus 로고
    • Heterologus protection against influenza by injeciton of DNA encoding a viral protein
    • Ulmer JB, Donnelly JJ, Packer SE, et al. Heterologus protection against influenza by injeciton of DNA encoding a viral protein. Science 1993;259:1745-49
    • (1993) Science , vol.259 , pp. 1745-1749
    • Ulmer, J.B.1    Donnelly, J.J.2    Packer, S.E.3
  • 3
    • 0035961553 scopus 로고    scopus 로고
    • Vaxfectin enhances the humoral immune response to plasmid DNA-encoded antigens
    • Hartikka J, Bozoukova V, Ferrari M, et al. Vaxfectin enhances the humoral immune response to plasmid DNA-encoded antigens. Vaccine 2001;19:1911-23
    • (2001) Vaccine , vol.19 , pp. 1911-1923
    • Hartikka, J.1    Bozoukova, V.2    Ferrari, M.3
  • 4
    • 70350060159 scopus 로고    scopus 로고
    • Vaxfectin a cationic lipid-based adjuvant for protein-based influenza vaccines
    • Hartikka J, Bozoukova V, Yang CK, et al. Vaxfectin, a cationic lipid-based adjuvant for protein-based influenza vaccines. Vaccine 2009;27:6399-403
    • (2009) Vaccine , vol.27 , pp. 6399-6403
    • Hartikka, J.1    Bozoukova, V.2    Yang, C.K.3
  • 6
    • 0036555126 scopus 로고    scopus 로고
    • Liposomal delivery of CTL epitopes to dendritic cells
    • Chikh sG, Schutze-Redelmeier MP. Liposomal delivery of CTL epitopes to dendritic cells. Biosci Rep 2002;22:339-53
    • (2002) Biosci. Rep. , vol.22 , pp. 339-353
    • Chikh, G.1    Schutze-Redelmeier, M.P.2
  • 7
    • 0035859294 scopus 로고    scopus 로고
    • Vaxfectin enhances antigen specific antibody titers and maintains Th1 type immune responses to plasmid DNA immunization
    • Reyes L, Hartikka J, Bozoukova V, et al. Vaxfectin enhances antigen specific antibody titers and maintains Th1 type immune responses to plasmid DNA immunization. Vaccine 2001;19:3778-86
    • (2001) Vaccine , vol.19 , pp. 3778-3786
    • Reyes, L.1    Hartikka, J.2    Bozoukova, V.3
  • 8
    • 32544448799 scopus 로고    scopus 로고
    • Vaxfectin enhances immunogenicity and protective efficacy of P. yoelii circumsporozoite DNA vaccines
    • Sedegah M, Rogers WO, Belmonte A, et al. Vaxfectin enhances immunogenicity and protective efficacy of P. yoelii circumsporozoite DNA vaccines. Vaccine 2006;24:1921-7
    • (2006) Vaccine , vol.24 , pp. 1921-1927
    • Sedegah, M.1    Rogers, W.O.2    Belmonte, A.3
  • 9
    • 77949654293 scopus 로고    scopus 로고
    • Vaxfectin enhances both antibody and in vitro T cell responses to each component of a 5-gene plasmodium falciparum plasmid DNA vaccine mixture administered at low doses
    • Sedegah M, Rogers WO, Belmonte M, et al. Vaxfectin enhances both antibody and in vitro T cell responses to each component of a 5-gene Plasmodium falciparum plasmid DNA vaccine mixture administered at low doses. Vaccine 2010;28:3055-65
    • (2010) Vaccine , Issue.28 , pp. 3055-3065
    • Sedegah, M.1    Rogers, W.O.2    Belmonte, M.3
  • 10
    • 2442421044 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 2 DNA vaccine provides partial protection from acute baboon infection
    • Locher CP, Witt SA, Ashlock BM, et al. Human immunodeficiency virus type 2 DNA vaccine provides partial protection from acute baboon infection. Vaccine 2004;22:2261-72
    • (2004) Vaccine , vol.22 , pp. 2261-2272
    • Locher, C.P.1    Witt, S.A.2    Ashlock, B.M.3
  • 11
    • 49149086922 scopus 로고    scopus 로고
    • Use of vaxfectin adjuvant with DNA vaccine encoding the measles virus hemagglutinin and fusion proteins protects juvenile and infant rhesus macaques against measles virus
    • Pan CH, Jimenez GS, Nair N, et al. Use of Vaxfectin adjuvant with DNA vaccine encoding the measles virus hemagglutinin and fusion proteins protects juvenile and infant rhesus macaques against measles virus. Clin Vaccine Immunol 2008;15:1214-21
    • (2008) Clin. Vaccine Immunol. , vol.15 , pp. 1214-1221
    • Pan, C.H.1    Jimenez, G.S.2    Nair, N.3
  • 12
    • 35348960407 scopus 로고    scopus 로고
    • Vaxfectin-formulated influenza DNA vaccines encoding NP and M2 viral proteins protect mice against lethal viral challenge
    • Jimenez GS, Planchon R, Wei Q, et al. Vaxfectin-formulated influenza DNA vaccines encoding NP and M2 viral proteins protect mice against lethal viral challenge. Hum Vaccin 2007;3:157-64
    • (2007) Hum. Vaccin. , vol.3 , pp. 157-164
    • Jimenez, G.S.1    Planchon, R.2    Wei, Q.3
  • 13
    • 46349102241 scopus 로고    scopus 로고
    • Plasmid DNA-based vaccines protect mice and ferrets against lethal challenge with A/Vietnam/1203/04 H5N1 influenza virus
    • Lalor PA, Webby RJ, Morrow J, et al. Plasmid DNA-based vaccines protect mice and ferrets against lethal challenge with A/Vietnam/1203/04 (H5N1) influenza virus. J Infect Dis 2008;197:1643-52
    • (2008) J. Infect. Dis. , vol.197 , pp. 1643-1652
    • Lalor, P.A.1    Webby, R.J.2    Morrow, J.3
  • 14
    • 75149178610 scopus 로고    scopus 로고
    • Rapid development of a vaxfectin-adjuvanted DNA vaccine encoding pandemic swine-origin influenza A virus A H1N1 hemagglutinin
    • Ye M, Wei Q, Kristin R, et al. Rapid development of a Vaxfectin-adjuvanted DNA vaccine encoding pandemic swine-origin influenza A virus A (H1N1) hemagglutinin. Gene Ther Regul 2009;4:44-55
    • (2009) Gene. Ther. Regul. , vol.4 , pp. 44-55
    • Ye, M.1    Wei, Q.2    Kristin, R.3
  • 15
    • 34548492300 scopus 로고    scopus 로고
    • Vaccination with polymerase chain reaction-generated linear expression cassettes protects mice against lethal influenza a challenge
    • Vilalta A, Jimenez G, Rusalov D, et al. Vaccination with polymerase chain reaction-generated linear expression cassettes protects mice against lethal influenza A challenge. Hum Gene Ther 2007;18:763-71
    • (2007) Hum. Gene. Ther. , vol.18 , pp. 763-771
    • Vilalta, A.1    Jimenez, G.2    Rusalov, D.3
  • 17
    • 33744792063 scopus 로고    scopus 로고
    • Toxicological safety evaluation of DNA plasmid vaccines against HIV-1, Ebola, Severe Acute Respiratory Syndrome, or West Nile virus is similar despite differing plasmid backbones or gene-inserts
    • DOI 10.1093/toxsci/kfj170
    • Sheets RL, Stein J, Manetz TS, et al. Toxicological safety evaluation of DNA plasmid vaccines against HIV-1, Ebola, Severe Acute Respiratory Syndrome, or West Nile virus is similar despite differing plasmid backbones or gene-inserts. Toxicol Sci 2006;91:620-30 (Pubitemid 43827314)
    • (2006) Toxicological Sciences , vol.91 , Issue.2 , pp. 620-630
    • Sheets, R.L.1    Stein, J.2    Manetz, T.S.3    Andrews, C.4    Bailer, R.5    Rathmann, J.6    Gomez, P.L.7
  • 18
    • 26644468124 scopus 로고    scopus 로고
    • II cationic lipid-formulated plasmid DNA-based Bacillus anthracis vaccine: Evaluation of plasmid DNA persistence and integration potential
    • Vilalta A, Mahajan RK, Hartikka J, et al. II. Cationic lipid-formulated plasmid DNA-based Bacillus anthracis vaccine: evaluation of plasmid DNA persistence and integration potential. Hum Gene Ther 2005;16:1151-6
    • (2005) Hum. Gene. Ther. , vol.16 , pp. 1151-1156
    • Vilalta, A.1    Mahajan, R.K.2    Hartikka, J.3
  • 19
    • 26644466086 scopus 로고    scopus 로고
    • I. Poloxamer-formulated plasmid DNA-based human cytomegalovirus vaccine: Evaluation of plasmid DNA biodistribution/persistence and integration
    • Vilalta A, Mahajan RK, Hartikka J, et al. I. Poloxamer-formulated plasmid DNA-based human cytomegalovirus vaccine: evaluation of plasmid DNA biodistribution/persistence and integration. Hum Gene Ther 2005;16:1143-50
    • (2005) Hum. Gene. Ther. , vol.16 , pp. 1143-1150
    • Vilalta, A.1    Mahajan, R.K.2    Hartikka, J.3
  • 20
    • 0033586277 scopus 로고    scopus 로고
    • Plasmid DNA malaria vaccine: The potential for genomic integration after intramuscular injection
    • Martin T, Parker SE, Hedstrom R, et al. Plasmid DNA malaria vaccine: the potential for genomic integration after intramuscular injection. Hum Gene Ther 1999;10:759-68
    • (1999) Hum. Gene. Ther. , vol.10 , pp. 759-768
    • Martin, T.1    Parker, S.E.2    Hedstrom, R.3
  • 22
    • 77649188963 scopus 로고    scopus 로고
    • Phase 1 clinical trials of the safety and immunogenicity of adjuvanted plasmid DNA vaccines encoding influenza a virus H5 hemagglutinin
    • Smith LR, Wloch MK, Ye M, et al. Phase 1 clinical trials of the safety and immunogenicity of adjuvanted plasmid DNA vaccines encoding influenza A virus H5 hemagglutinin. Vaccine 2010;28:2565-72
    • (2010) Vaccine , Issue.28 , pp. 2565-2572
    • Smith, L.R.1    Wloch, M.K.2    Ye, M.3
  • 24
    • 35348880906 scopus 로고    scopus 로고
    • Preparing for a possible pandemic: Influenza A/H5N1 vaccine development
    • Keitel WA, Atmar RL. Preparing for a possible pandemic: influenza A/H5N1 vaccine development. Curr Opin Pharmacol 2007;7:484-90
    • (2007) Curr. Opin. Pharmacol. , vol.7 , pp. 484-490
    • Keitel, W.A.1    Atmar, R.L.2
  • 25
    • 0035339389 scopus 로고    scopus 로고
    • Three different vaccines based on the 140-amino acid MUC1 peptide with seven tandemly repeated tumor-specific epitopes elicit distinct immune effector mechanisms in wild-type versus MUC1-transgenic mice with different potential for tumor rejection
    • Soares MM, Mehta V, Finn OJ. Three different vaccines based on the 140-amino acid MUC1 peptide with seven tandemly repeated tumor-specific epitopes elicit distinct immune effector mechanisms in wild-type versus MUC1-transgenic mice with different potential for tumor rejection. J Immunol 2001;166:6555-63
    • (2001) J. Immunol. , vol.166 , pp. 6555-6563
    • Soares, M.M.1    Mehta, V.2    Finn, O.J.3
  • 26
    • 0029664297 scopus 로고    scopus 로고
    • Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization
    • USA
    • Raz E, Tighe H, Sato Y, et al. Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization. Proc Natl Acad Sci USA 1996;93:5141-5
    • (1996) Proc. Natl. Acad. Sci. , vol.93 , pp. 5141-5145
    • Raz, E.1    Tighe, H.2    Sato, Y.3
  • 27
    • 70649091130 scopus 로고    scopus 로고
    • Analysis of biomarkers after intramuscular injection of Vaxfectin-formulated hCMV gB plasmid DNA
    • Vilalta A, Shlapobersky M, Wei Q, et al. Analysis of biomarkers after intramuscular injection of Vaxfectin-formulated hCMV gB plasmid DNA. Vaccine 2009;27:7409-17
    • (2009) Vaccine , vol.27 , pp. 7409-7417
    • Vilalta, A.1    Shlapobersky, M.2    Wei, Q.3
  • 28
    • 0033812475 scopus 로고    scopus 로고
    • Building better vaccines: How apoptotic cell death can induce inflammation and activate innate and adaptive immunity
    • Restifo NP. Building better vaccines: how apoptotic cell death can induce inflammation and activate innate and adaptive immunity. Curr Opin Immunol 2000;12:597-603
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 597-603
    • Restifo, N.P.1
  • 29
    • 70350060040 scopus 로고    scopus 로고
    • Vaxfectin-adjuvanted seasonal influenza protein vaccine: Correlation of systemic and local immunological markers with formulation parameters
    • Shlapobersky M, Wei Q, Sullivan S, Vilalta A. Vaxfectin-adjuvanted seasonal influenza protein vaccine: correlation of systemic and local immunological markers with formulation parameters. Vaccine 2009;27:6404-10
    • (2009) Vaccine , vol.27 , pp. 6404-6410
    • Shlapobersky, M.1    Wei, Q.2    Sullivan, S.3    Vilalta, A.4
  • 30
    • 61849170035 scopus 로고    scopus 로고
    • TLRs and innate immunity
    • Beutler BA. TLRs and innate immunity. Blood 2009;113:1399-407
    • (2009) Blood , vol.113 , pp. 1399-1407
    • Beutler, B.A.1
  • 31
    • 33845905223 scopus 로고    scopus 로고
    • Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling
    • Gavin AL, Hoebe K, Duong B, et al. Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling. Science 2006;314:1936-8
    • (2006) Science , vol.314 , pp. 1936-1938
    • Gavin, A.L.1    Hoebe, K.2    Duong, B.3
  • 32
    • 0029885750 scopus 로고    scopus 로고
    • IL-12 is an effective adjuvant to recombinant vaccinia virus-based tumor vaccines: Enhancement by simultaneous B7-1 expression
    • Rao JB, Chamberlain RS, Bronte V, et al. IL-12 is an effective adjuvant to recombinant vaccinia virus-based tumor vaccines: enhancement by simultaneous B7-1 expression. J Immunol 1996;156:3357-65
    • (1996) J Immunol , vol.156 , pp. 3357-3365
    • Rao, J.B.1    Chamberlain, R.S.2    Bronte, V.3
  • 33
    • 0033046593 scopus 로고    scopus 로고
    • The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens
    • Waldmann TA, Tagaya Y. The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens. Annu Rev Immunol 1999;17:19-49
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 19-49
    • Waldmann, T.A.1    Tagaya, Y.2
  • 34
    • 0037037568 scopus 로고    scopus 로고
    • Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T cells
    • Judge AD, Zhang X, Fujii H, et al. Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T cells. J Exp Med 2002;196:935-46
    • (2002) J. Exp. Med. , vol.196 , pp. 935-946
    • Judge, A.D.1    Zhang, X.2    Fujii, H.3
  • 35
    • 0036084818 scopus 로고    scopus 로고
    • Improved tuberculosis DNA vaccines by formulation in cationic lipids
    • DSouza S, Rosseels V, Denis O, et al. Improved tuberculosis DNA vaccines by formulation in cationic lipids. Infect Immun 2002;70:3681-8
    • (2002) Infect. Immun. , vol.70 , pp. 3681-3688
    • D'Souza, S.1    Rosseels, V.2    Denis, O.3
  • 36
    • 0038043336 scopus 로고    scopus 로고
    • Enhancing effect of vaxfectin on the ability of a Japanese encephalitis DNA vaccine to induce neutralizing antibody in mice
    • Nukuzuma C, Ajiro N, Wheeler CJ, Konishi E. Enhancing effect of vaxfectin on the ability of a Japanese encephalitis DNA vaccine to induce neutralizing antibody in mice. Viral Immunol 2003;16:183-9
    • (2003) Viral. Immunol. , vol.16 , pp. 183-189
    • Nukuzuma, C.1    Ajiro, N.2    Wheeler, C.J.3    Konishi, E.4
  • 37
    • 33645550655 scopus 로고    scopus 로고
    • Sustained protective rabies neutralizing antibody titers after administration of cationic lipid-formulated pDNA vaccine
    • Margalith M, Vilalta A. Sustained protective rabies neutralizing antibody titers after administration of cationic lipid-formulated pDNA vaccine. Genet Vaccines Ther 2006;4:2-7
    • (2006) Genet. Vaccines. Ther. , vol.4 , pp. 2-7
    • Margalith, M.1    Vilalta, A.2
  • 38
    • 33645064822 scopus 로고    scopus 로고
    • Priming but not boosting with plasmid DNA encoding mycolyl-transferase Ag85A from mycobacterium tuberculosis increases the survival time of mycobacterium bovis BCG vaccinated mice against low dose intravenous challenge with M tuberculosis H37Rv
    • Romano M, DSouza S, Adnet PY, et al. Priming but not boosting with plasmid DNA encoding mycolyl-transferase Ag85A from Mycobacterium tuberculosis increases the survival time of Mycobacterium bovis BCG vaccinated mice against low dose intravenous challenge with M. tuberculosis H37Rv. Vaccine 2006;24:3353-64
    • (2006) Vaccine , vol.24 , pp. 3353-3364
    • Romano, M.1    D'Souza, S.2    Adnet, P.Y.3
  • 39
    • 18744390472 scopus 로고    scopus 로고
    • Salivary gland delivery of pDNA-cationic lipoplexes elicits systemic immune responses
    • Sankar V, Baccaglini L, Sawdey M, et al. Salivary gland delivery of pDNA-cationic lipoplexes elicits systemic immune responses. Oral Dis 2002;8:275-81
    • (2002) Oral. Dis. , vol.8 , pp. 275-281
    • Sankar, V.1    Baccaglini, L.2    Sawdey, M.3
  • 40
    • 4544375374 scopus 로고    scopus 로고
    • A cationic lipid-formulated plasmid DNA vaccine confers sustained antibody-mediated protection against aerosolized anthrax spores
    • USA.
    • Hermanson G, Whitlow V, Parker S, et al. A cationic lipid-formulated plasmid DNA vaccine confers sustained antibody-mediated protection against aerosolized anthrax spores. Proc Natl Acad Sci USA 2004;101:13601-6
    • (2004) Proc. Natl. Acad. Sci. , vol.101 , pp. 13601-13606
    • Hermanson, G.1    Whitlow, V.2    Parker, S.3
  • 41
    • 33646838050 scopus 로고    scopus 로고
    • Comparison of the immunological memory after DNA vaccination and protein vaccination against anthrax in sheep
    • Hahn UK, Aichler M, Boehm R, Beyer W. Comparison of the immunological memory after DNA vaccination and protein vaccination against anthrax in sheep. Vaccine 2006;24:4595-7
    • (2006) Vaccine , vol.24 , pp. 4595-4597
    • Hahn, U.K.1    Aichler, M.2    Boehm, R.3    Beyer, W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.