Postoperative whole pelvic radiotherapy plus concurrent chemotherapy versus extended-field irradiation for early-stage cervical cancer patients with multiple pelvic lymph node metastases

Gynecologic Oncology

Volumn 120, Issue 1, 2011, Pages 94-100

  Mabuchi, Seiji ^a   Okazawa, Mika ^b   Isohashi, Fumiaki ^a   Ohta, Yukinobu ^b   Maruoka, Shintaroh ^a   Yoshioka, Yasuo ^a   Enomoto, Takayuki ^a   Morishige, Kenichirou ^a,c   Kamiura, Shoji ^b   Kimura, Tadashi ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA MEDICAL CENTER FOR CANCER AND CARDIOVASCULAR DISEASES   (Japan)

^c GIFU UNIVERSITY   (Japan)

Author keywords

Cervical cancer; Concurrent chemoradiotherapy; Extended field radiotherapy; Lymph nodes metastases; Radical hysterectomy

Indexed keywords

NEDAPLATIN;

ADULT; ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CLINICAL EFFECTIVENESS; COMPARATIVE STUDY; EARLY CANCER; EXTENDED FIELD IRRADIATION; EXTERNAL BEAM RADIOTHERAPY; FEMALE; HUMAN; INTESTINE OBSTRUCTION; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MULTIPLE CYCLE TREATMENT; NEUTROPENIA; OVERALL SURVIVAL; PELVIS LYMPH NODE; PELVIS LYMPHADENECTOMY; POSTOPERATIVE CARE; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; RADIATION DERMATITIS; RADICAL HYSTERECTOMY; RETROSPECTIVE STUDY; THROMBOCYTOPENIA; TREATMENT OUTCOME; UTERINE CERVIX CARCINOMA; WHOLE PELVIS RADIOTHERAPY;

ANTINEOPLASTIC AGENTS; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; HYSTERECTOMY; LYMPH NODE EXCISION; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; ORGANOPLATINUM COMPOUNDS; POSTOPERATIVE CARE; RADIOTHERAPY DOSAGE; RETROSPECTIVE STUDIES; UTERINE CERVICAL NEOPLASMS;

EID: 78649903822     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2010.09.016     Document Type: Article

References (38)

1. F. Landoni, A. Maneo, A. Colombo, F. Placa, R. Milani, and P. Perego Randomized study of radical surgery versus radiotherapy for stage Ib-IIa cervical cancer Lancet 350 1997 535 540
2. G.W. Morley, and J.C. Seski Radical pelvic surgery versus radiation therapy for stage I carcinoma of the cervix (exclusive of microinvasion) Am J Obstet Gynecol 126 1976 785 798
3. C.A. Perez, H.M. Camel, M.S. Kao, and M.A. Hederman Randomized study of preoperative radiation and surgery or irradiation alone in the treatment of stage IB and IIA carcinoma of the uterine cervix: final report Gynecol Oncol 27 1987 129 140
4. T. Kasamatsu, T. Onda, M. Sawada, T. Kato, S. Ikeda, and Y. Sasajima Radical hysterectomy for FIGO stage I-IIB adenocarcinoma of the uterine cervix Br J Cancer 100 2009 1400 1405
5. R.A. Samlal, J. van der Velden, M.S. Schilthuis, D. González González, F.J. Ten Kate, and A.A. Hart Identification of high-risk groups among node-positive patients with stage IB and IIA cervical carcinoma Gynecol Oncol 64 1997 463 467
6. G. Delgado, B. Bundy, R. Zaino, B.U. Sevin, W.T. Creasman, and F. Major Prospective surgical-pathological study of disease-free interval in patients with stage IB squamous cell carcinoma of the cervix: a Gynecologic Oncology Group study Gynecol Oncol 38 1990 352 357
7. A.F. Fuller Jr., N. Elliott, C. Kosloff, W.J. Hoskins, and J.L. Lewis Jr. Determinants of increased risk for recurrence in patients undergoing radical hysterectomy for stage IB and IIA carcinoma of the cervix Gynecol Oncol 33 1989 34 39
8. B.J. Monk, D.S. Cha, J.L. Walker, R.A. Burger, N.S. Ramsinghani, and A. Manetta Extent of disease as an indication for pelvic radiation following radical hysterectomy and bilateral pelvic lymph node dissection in the treatment of stage IB and IIA cervical carcinoma Gynecol Oncol 54 1994 4 9
9. N. Sakuragi, C. Satoh, N. Takeda, H. Hareyama, M. Takeda, and R. Yamamoto Incidence and distribution pattern of pelvic and paraaortic lymph node metastasis in patients with stages IB, IIA, and IIB cervical carcinoma treated with radical hysterectomy Cancer 85 1999 1547 1554
10. J.H. Kim, H.J. Kim, S. Hong, H.G. Wu, and S.W. Ha Post-hysterectomy radiotherapy in FIGO stage IB-IIB uterine cervical carcinoma Gynecol Oncol 96 2005 407 414
11. M. Rotman, T.F. Pajak, K. Choi, M. Clery, V. Marcial, and P.W. Grigsby Prophylactic extended-field irradiation of para-aortic lymph nodes in stages IIB and bulky IB and IIA cervical carcinomas. Ten-year treatment results of RTOG 79-20 JAMA 274 1995 387 393
12. M. Morris, P.J. Eifel, J. Lu, P.W. Grigsby, C. Levenback, and R.E. Stevens Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer N Engl J Med 340 1999 1137 1143
13. W.A. Peters III, P.Y. Liu, R.J. Barrett 2nd, R.J. Stock, B.J. Monk, and J.S. Berek Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix J Clin Oncol 18 2000 1606 1613
14. National Comprehensive Cancer Network clinical practice guidelines in oncology, Cervical Cancer-v.1.2011. http://www.nccn.org/professionals/physician- gls/PDF/cervical.pdf (Accessed 10/11/2010).
15. National Cancer Institute clinical announcement. Concurrent chemoradiation for cervical cancer. February, 1999 (http://www.cancer.gov/ newscenter/cervicalcancer ) (Accessed 5/31/2010).
16. S. Mabuchi, K. Morishige, F. Isohashi, Y. Yoshioka, T. Takeda, and T. Yamamoto Postoperative concurrent nedaplatin-based chemoradiotherapy improves survival in early-stage cervical cancer patients with adverse risk factors Gynecol Oncol 115 2009 482 487
17. T. Inoue, and K. Morita Long-term observation of patients treated by postoperative extended-field irradiation for nodal metastases from cervical carcinoma stages IB, IIA, and IIB Gynecol Oncol 58 1995 4 10
18. S. Mabuchi, H. Ugaki, F. Isohashi, Y. Yoshioka, K. Temma, and N. Yada-Hashimoto Concurrent weekly nedaplatin, external beam radiotherapy and high-dose-rate brachytherapy in patients with FIGO stage IIIb cervical cancer: a comparison with a cohort treated by radiotherapy alone Gynecol Obstet Invest 69 2010 224 232
19. Y. Kobayashi, T. Ohara, Y. Wada, Y. Okuda, H. Kondo, and Y. Okuma Concurrent chemoradiotherapy with nedaplatin after radical hysterectomy in patients with stage IB and II cervical cancer J Obstet Gynaecol Res 35 2009 490 494
20. J.D. Cox, J. Stetz, and T.F. Pajak Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC) Int J Radiat Oncol Biol Phys 31 1995 1341 1346
21. S. Mabuchi, F. Isohashi, Y. Yoshioka, K. Temma, T. Takeda, T. Yamamoto, T. Enomoto, K. Morishige, T. Inoue, and T. Kimura Prognostic factors for survival in patients with recurrent cervical cancer previously treated with radiotherapy Int J Gynecol Cancer 20 2010 834 840
22. R.K. Brookland, S. Rubin, and B.F. Danoff Extended field irradiation in the treatment of patients with cervical carcinoma involving biopsy proven para-aortic nodes Int J Radiat Oncol Biol Phys 10 1984 1875 1879
23. N. Sakuragi Up-to-date management of lymph node metastasis and the role of tailored lymphadenectomy in cervical cancer Int J Clin Oncol 12 2007 165 175
24. G. Michel, P. Morice, D. Castaigne, M. Leblanc, A. Rey, and P. Duvillard Lymphatic spread in stage Ib and II cervical carcinoma: anatomy and surgical implications Obstet Gynecol 91 1998 360 363
25. M.L. Berman, H. Keys, W. Creasman, P. DiSaia, B. Bundy, and J. Blessing Survival and patterns of recurrence in cervical cancer metastatic to periaortic lymph nodes (a Gynecologic Oncology Group study) Gynecol Oncol 19 1984 8 16
26. B.J. Monk, J. Wang, S. Im, R.J. Stock, W.A. Peters III, and P.Y. Liu Rethinking the use of radiation and chemotherapy after radical hysterectomy: a clinical-pathologic analysis of a Gynecologic Oncology Group/Southwest Oncology Group/Radiation Therapy Oncology Group trial Gynecol Oncol 96 2005 721 728
27. F. Kanzawa, Y. Matsushima, H. Nakano, K. Nakagawa, H. Takahashi, and Y. Sasaki Antitumor activity of a new platinum compound (glycolate-o, o′) diammineplatinum (II) (254-S), against non-small cell lung carcinoma grown in a human tumor clonogenic assay system Anticancer Res 8 1988 323 327
28. B.J. Monk, D.S. Alberts, R.A. Burger, P.T. Fanta, A.V. Hallum III, and K.D. Hatch In vitro phase II comparison of the cytotoxicity of a novel platinum analog, nedaplatin (254-S), with that of cisplatin and carboplatin against fresh, human cervical cancers Gynecol Oncol 71 1998 308 312
29. Y. Sasaki, T. Shinkai, K. Eguchi, T. Tamura, Y. Ohe, and T. Ohmori Prediction of the antitumor activity of new platinum analogs based on their ex vivo pharmacodynamics as determined by bioassay Cancer Chemother Pharmacol 27 1991 263 270
30. T. Uehara, H. Watanabe, F. Itoh, S. Inoue, H. Koshida, and M. Nakamura Nephrotoxicity of a novel antineoplastic platinum complex, nedaplatin: a comparative study with cisplatin in rats Arch Toxicol 79 2005 451 460
31. Y. Kawai, S. Taniuchi, S. Okahara, M. Nakamura, and M. Gemba Relationship between cisplatin or nedaplatin-induced nephrotoxicity and renal accumulation Biol Pharm Bull 28 2005 1385 1388
32. J. Kodama, M. Takemoto, N. Seki, K. Nakamura, A. Hongo, and S. Kanazawa Phase I study of weekly nedaplatin and concurrent pelvic radiotherapy as adjuvant therapy after radical surgery for cervical cancer Int J Gynecol Cancer 18 2008 1037 1041
33. Hasselle MD, Rose BS, Kochanski JD, Nath SK, Bafana R, Yashar CM, Hasan Y, Roeske JC, Mundt AJ, Mell LK. Clinical outcomes of intensity-modulated pelvic radiation therapy for carcinoma of the cervix. Int J Radiat Oncol Biol Phys. in press. doi:10.1016/j.ijrobp.2010.04.041.
34. M.A. Varia, B.N. Bundy, G. Deppe, R. Mannel, H.E. Averette, and P.G. Rose Cervical carcinoma metastatic to para-aortic nodes: extended field radiation therapy with concomitant 5-fluorouracil and cisplatin chemotherapy: a Gynecologic Oncology Group study Int J Radiat Oncol Biol Phys 42 1998 1015 1023
35. P.W. Grigsby, C.A. Perez, K.S. Chao, T. Herzog, D.G. Mutch, and J. Rader Radiation therapy for carcinoma of the cervix with biopsy-proven positive para-aortic lymph nodes Int J Radiat Oncol Biol Phys 49 2001 733 738
36. E. Podczaski, J.A. Stryker, P. Kaminski, B. Ndubisi, J. Larson, and K. DeGeest Extended-field radiation therapy for carcinoma of the cervix Cancer 66 1990 251 258
37. T. Kodaira, N. Fuwa, T. Nakanishi, H. Tachibana, T. Nakamura, and N. Tomita Prospective study of alternating chemoradiotherapy consisting of extended-field dynamic conformational radiotherapy and systemic chemotherapy using 5-FU and nedaplatin for patients in high-risk group with cervical carcinoma Int J Radiat Oncol Biol Phys 73 2009 251 258
38. S. Beriwal, G.N. Gan, D.E. Heron, R.N. Selvaraj, H. Kim, and R. Lalonde Early clinical outcome with concurrent chemotherapy and extended-field, intensity-modulated radiotherapy for cervical cancer Int J Radiat Oncol Biol Phys 68 2007 166 171