Recent insights into a new hydrodynamics of the cerebrospinal fluid

Brain Research Reviews

Volumn 65, Issue 2, 2011, Pages 99-112

  Bulat, Marin ^a   Klarica, Marijan ^a  

^a UNIVERSITY OF ZAGREB   (Croatia)

Author keywords

Capillary osmotic counterpressure; Cerebral capillaries; Cerebrospinal fluid (CSF) hydrodynamics; CSF interstial fluid mixing; Elimination distribution rate; Transcapillary fluid filtration reabsorption

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; AQUAPORIN; AQUAPORIN 1; AQUAPORIN 4; AQUAPORIN 9; DEUTERIUM OXIDE; HORSERADISH PEROXIDASE; INULIN; METHOTREXATE; PENICILLIN G; PHENOLSULFONPHTHALEIN; PROBENECID; SERUM ALBUMIN I 131; TRITIUM OXIDE;

ACTIVE TRANSPORT; AORTA OCCLUSION; ARTERY LIGATION; BLOOD BRAIN BARRIER; BLOOD LEVEL; BODY FLUID; BRAIN AQUEDUCT; BRAIN VENTRICLE; CAPILLARY PERMEABILITY; CAPILLARY WALL; CAT; CELL JUNCTION; CEREBROSPINAL FLUID; CEREBROSPINAL FLUID FLOW; CEREBROSPINAL FLUID PRESSURE; CHOROID PLEXUS; DOG; EXTRAVASCULAR SPACE; FLUID BALANCE; HALF LIFE TIME; HUMAN; HYDRAULIC CONDUCTIVITY; HYDRODYNAMICS; HYDROSTATIC PRESSURE; MACROMOLECULE; MEAN RESIDENCE TIME; MICROVASCULATURE; MONKEY; NONHUMAN; OSMOTIC PRESSURE; PLASMA OSMOLALITY; PRESSURE GRADIENT; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN TRANSPORT; PULSE PRESSURE; RABBIT; REGULATORY MECHANISM; REVIEW; SUBARACHNOID SPACE; WATER ABSORPTION;

ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; CEREBRAL VENTRICLES; CEREBROSPINAL FLUID; CEREBROSPINAL FLUID PRESSURE; CEREBROVASCULAR CIRCULATION; HUMANS; HYDRODYNAMICS; SUBARACHNOID SPACE;

EID: 78649903759     PISSN: 01650173     EISSN: 18726321     Source Type: Journal    
DOI: 10.1016/j.brainresrev.2010.08.002     Document Type: Review

References (88)

1. Alperin N., Hushek S.G., Lee S.H., Sivaramakrishnan A., Lichtor T. MRI study of cerebral blood flow and CSF flow dynamics in an upright posture: the effect of posture on the intracranial compliance and pressure. Acta Neurochir. 2005, Suppl. 95:177-181.
2. Baumgarten C.M., Feher J.J. Osmosis and regulation of cell volume. Cell Physiology Sourcebook 2001, 319-355. Academic Press, San Diego. N. Sperelakis (Ed.).
3. Bering E.A. Water exchange of central nervous system and cerebrospinal fluid. J. Neurosurg. 1952, 9:275-287.
4. Bering E.A., Sato O. Hydrocephalus: changes in formation and absorption of cerebrospinal fluid within the cerebral ventricles. J. Neurosurg. 1963, 20:1050-1063.
5. Bolwing T.G., Lassen N.A. The diffusion permeability to water of the rat blood-brain barrier. Acta Physiol. Scand. 1975, 93:415-422.
6. Bradbury M.W.B., Westorp R.J. Lymphatics and drainage of cerebrospinal fluid. Hydrocephalus 1984, 69-81. Raven Press, New York. K. Shapiro, A. Marmarou, H. Portnoy (Eds.).
7. Brodbelt A., Stoodley M. CSF pathways: a review. Br. J. Neurosurg. 2007, 21:510-520.
8. Brown P.D., Davies S.L., Speake T., Millar I.D. Molecular mechanisms of cerebrospinal fluid production. Neuroscience 2004, 129:957-970.
9. Bulat M. Monoamine metabolites in the cerebrospinal fluid: indicators of the biochemical status of monoaminoergic neurons in the central nervous system. Ciba Foundation Symposium 1974, 22:243-256. Elsevier, Amsterdam. G.E.W. Wolstenholme, D.W. Fitzsimons (Eds.).
10. Bulat M. On the cerebral origin of 5-hydroxyindoleacetic acid in the lumbar cerebrospinal fluid. Brain Res. 1977, 122:388-391.
11. Bulat M. Dynamics and statics of the cerebrospinal fluid: the classical and a new hypothesis. Intracranial Pressure VIII 1993, 726-730. Springer-Verlag, Berlin. C.J.J. Avezaat, J.H.M. van Eijndhoven, A.I.R. Mass, J.T.J. Tans (Eds.).
12. Bulat M., Živković B. Origin of 5-hydroxyindoleacetic acid in the spinal fluid. Science 1971, 173:738-740.
13. Bulat M., Živković B. Exchange of 5-hydoxyindoleacetic acid between the spinal cord and lumbar cerebrospinal fluid. J. Physiol. (London) 1978, 275:191-197.
14. Bulat M., Živković B. Neurochemical study of the cerebrospinal fluid. Research Methods in Neurochemistry 1978, Vol. 4:57-89. Plenum Press, New York.
15. Bulat M., Klarica M. Osmotic control of intracranial pressure. Period. Biol. 2001, 103:293-296.
16. Bulat M., Klarica M. Fluid filtration and reabsorption across microvascular walls: control by oncotic or osmotic pressure?. Period Biol. 2005, 107:147-152.
17. Bulat M., Lacković Z., Jakupčević M., Damjanov I. 5-Hydroxyindoleacetic acid in the lumbar fluid-a specific indicator of spinal cord injury. Science 1974, 185:527-528.
18. Bulat M., Lupret V., Orešković D., Klarica M. Transventricular and transpial absorption of cerebrospinal fluid into cerebral microvessels. Coll. Antropol. 2008, 32(Suppl 1):43-50.
19. Butler A. Correlated physiologic and structural studies of CSF absorption. Hydrocephalus 1984, 41-57. Raven Press, New York. K. Shapiro, A. Marmarou, H. Portnoy (Eds.).
20. Crone C. The permeability of capillaries in various organs as determined by use of the indicator diffusion method. Acta Physiol. Scand. 1963, 58:292-305.
21. Cserr H.F. Convection of brain interstitial fluid. Hydrocephalus 1984, 59-68. Raven Press, New York. K. Shapiro, A. Marmarou, H. Portnoy (Eds.).
22. Cserr H.F. Role of secretion and bulk flow of brain interstitial fluid in brain volume regulation. Annals N.Y. Acad. Sci. 1988, 529:9-20.
23. Davson H. Formation and drainage of the cerebrospinal fluid. Hydrocephalus 1984, 3-40. Raven Press, New York. K. Shapiro, A. Marmarou, H. Portnoy (Eds.).
24. Di Rocco C. Hydrocephalus and cerebrospinal fluid pulses. Hydrocephalus 1984, 231-249. Raven Press, New York. K. Shapiro, A. Marmarou, H. Portnoy (Eds.).
25. Donato T., Shapira Y., Artru A., Powers K. Effect of mannitol on cerebrospinal fluid dynamics and brain tissue edema. Anesth. Analg. 1994, 78:58-66.
26. Edsbagge M., Tisel M., Jacobsson L., Wikkelso C. Spinal CSF absorption in healthy individuals. Am. J. Physiol. 2004, 287:R1450-R1455.
27. Enzmann D.R., Pelc N.J. Normal flow patterns of intracranial and spinal cerebrospinal fluid defined with phase-contrast cine MR imaging. Radiology 1991, 178:467-474.
28. Feinberg D.A., Mark A.S. Human brain motion and cerebrospinal fluid circulation demonstrated with MR velocity imaging. Radiology 1987, 163:793-799.
29. Fenstermacher J.D., Rapoport S.I. Blood-brain barrier. Handbook of Physiology, Microcirculation 1984, Vol. IV:969-1000. American Physiological Society, Bethesda MD.
30. Fenstermacher J.D., Kaye T. Drug "diffusion" within brain. Ann. N.Y. Acad. Sci. 1988, 531:29-39.
31. Foltz E.L. Hydrocephalus and CSF pulsatility: clinical and laboratories studies. Hydrocephalus 1984, 337-362. Raven Press, New York. K. Shapiro, A. Marmarou, H. Portnoy (Eds.).
32. Fraser P.A., Dallas A.D. Measurement of filtration coefficient in single cerebral microvessel of the frog. J. Physiol. (London) 1990, 423:343-361.
33. Greitz D. Radiological assessment of hydrocephalus: new theories and implications for therapy. Neurosurg Rev. 2004, 27:145-165.
34. Greitz D. Paradigm shift in hydrocephalus research in legacy of Dandy's pioneering work: rationale for third ventriculostomy in communicating hydrocephalus. Childs Nerv. Syst. 2007, 23:487-489.
35. Greitz D., Franck A., Nordell B. On the pulsatile nature of intracranial and spinal CSF-circulation demonstrated by MR imaging. Acta Radiol. 1993, 34:321-328.
36. Gunnarson E., Zelenina M., Aperia A. Regulation of brain aquaporins. Neuroscience 2004, 129:947-955.
37. Guyton A.C., Hall J.E. Textbook of Medical Physiology 1996, 301. W.B. Saunders, Philadelphia.
38. Hadaczek P., Yamashita Y., Mirek H., Tomas L., Bohn M.C., Noble C., Park J.W., Bankiewitz K. The "perivascular pump" driven by arterial pulsation is a powerful mechanism for the distribution of therapeutic molecules within the brain. Molec. Ther. 2006, 14:69-78.
39. Heisey S.R., Held D., Pappenheimer J.R. Bulk flow and diffusion in the cerebrospinal fluid system of the goat. Am. J. Physiol. 1962, 203:775-781.
40. Hindmarsh T. Computer cisternography for evaluation of CSF flow dynamics. Acta Radiol. Suppl. 1977, 355:269-279.
41. Holtzer G.J., de Lange S.A. Shunt-independent arrest of hydrocephalus. J. Neurosurg. 1973, 39:698-701.
42. Holtz J. Peripheral circulation: fundamental concepts, comparative aspects of control in specific vascular sections, and lymph flow. Comprehensive Human Physiology 1996, 1865-1915. Springer, Berlin. R. Greger, U. Windhorst (Eds.).
43. Huxley V.H., Curry F.E. Differential actions of albumin and plasma on capillary solute permeability. Am. J. Physiol. 1991, 260:H1645-H1654.
44. Johanson C.E., Duncan J.A., Klinge P.M., Brinker T., Stopa E.G., Silveberg G.D. Multiplicity of cerebrospinal fluid functions: new challenges in health and disease. Cerebrospinal Fluid Res. 2008, 5:10. 10.1186/1743-8544-5-10.
45. Katzman R., Pappius H.M. Brain Electrolytes and Fluid Metabolism 1973, Williams & Wilkins, Baltimore.
46. Keep R.F., Ennis S.R., Betz A.L. Blood-brain barrier ion transport. Introduction to the Blood-Brain Barrier 1998, 207-213. Cambridge University Press, Cambridge. W.M. Pardridge (Ed.).
47. Kimelberg H.K., Kung D., Watson R.E., Reiss F.L., Biddlecome S.M., Bourke R.S. Direct administration of methotrexate into the central nervous system of primates. Part 1: distribution and degradation of methotrexate in nervous and systemic tissue after intraventricular injection. J. Neurosurg. 1978, 48:883-894.
48. Klarica M., Orešković D., Božić B., Vukić M., Butković V., Bulat M. New experimental model of acute aqueductal blockage in cats: effects on cerebrospinal fluid pressure and the size of brain ventricles. Neuroscience 2009, 158:1397-1405.
49. Koh L., Zakharov A., Johnston M. Integration of the subarachnoid space and lymphatics: is it time to embrace a new concept of cerebrospinal fluid absorption?. Cerebrospinal Fluid Res. 2005, 2:6. 10.1186/1743-8454-2-6.
50. Landis E.M., Pappenheimer J.R. Exchange of substances through the capillary walls. Handbook of Physiology. Circulation Vol. II 1963, 961-1034. American Physiological Society, Washington DC. W.F. Hamilton, P. Dow (Eds.).
51. Martins A.N., Wiley J.K., Myers P. Dynamics of the cerebrospinal fluid and spinal dura mater. J. Neurol. Neurosurg. Psychiatry 1972, 35:468-473.
52. McComb J.G., Davson H., Hyman S., Weiss M.H. Cerebrospinal fluid drainage as influenced by ventricular pressure in the rabbit. J. Neurosurg. 1982, 56:790-797.
53. McComb J.G., Hyman S., Weiss M.H. Lymphatic drainage of cerebrospinal fluid in the cat. Hydrocephalus 1984, 83-98. Raven Press, New York. K. Shapiro, A. Marmarou, H. Portnoy (Eds.).
54. Michel C.C. Exchange of fluid and solutes across microvascular walls. The kidney 2000, 61-84. Lippincott Williams & Wilkins, Philadelphia. 3rd ed. D.W. Seldin, G. Giebisch (Eds.).
55. Milhorat T.H. Choroid plexus and cerebrospinal fluid production. Science 1969, 166:1514-1516.
56. Milhorat T.H., Hammock M.K., Chien T., Davis D.A. Normal rate of cerebrospinal fluid formation five years after bilateral choroid plexectomy, Case report. J. Neurosurg. 1976, 44:735-739.
57. Nebeshima S., Reese T.S., Landis D.M.D., Brightman M.W. Junctions in the meninges and marginal glia. J. Comp. Neurol. 1975, 164:127-169.
58. Orešković, D., Klarica, M., 2010. The formation of cerebrospinal fluid: nearly a hundred years of interpretations and misinterpretations. doi: 10.1016/j.brainresrev.2010.04.006.
59. Orešković D., Klarica M., Vukić M. Does the secretion and circulation of the cerebrospinal fluid really exist?. Med Hypotheses 2001, 56:622-624.
60. Orešković D., Klarica M., Vukić M. The formation and circulation of cerebrospinal fluid inside the cat brain ventricles: a fact or an illusion?. Neurosci. Lett. 2002, 327:103-106.
61. Pollay M. Formation of cerebrospinal fluid. J. Neurosurg. 1974, 42:665-673.
62. Raichle M.E. Neurogenic control of blood-brain barrier permeability. Acta Neuropathol. (Berl.) 1983, Suppl. VIII:75-79.
63. Renkin E.M., Crone C. Microcirculation and capillary exchange. Comprehensive Human Physiology 1996, 1965-1979. Springer, Berlin. R. Greger, U. Windhorst (Eds.).
64. Rennels M.L., Gregory T.F., Blaumanis O.R., Fujimoto K., Grady P.A. Evidence for a "paravascular" fluid circulation in the mammalian central nervous system, provided by rapid distribution of tracer protein throughout the brain from subarachnoid space. Brain Res. 1985, 326:47-63.
65. Riggs D.S. The Mathematical Approach to Physiological Problems 1972, M.I.T Press, Cambridge.
66. Shabo A.L., Maxwell D.S. The morphology of the arachnoid villi: a light and electron microscopic study in the monkey. J. Neurosurg. 1968, 29:451-463.
67. Shapiro H.M., Stomberg D.D., Lee D.R., Wiederhielm C.A. Dynamic pressures in the pial arterial microcirculation. Am. J. Physiol. 1971, 221:279-283.
68. Shapiro W.R., Young D.F., Mehta B.M. Methotrexate: distribution in the cerebrospinal fluid after intravenous, ventricular and lumbar injections. N. Engl. J. Med. 1975, 293:161-166.
69. Smith Q.R., Stoll J. Blood-brain barrier amino acid transport. Introduction to the Blood-Brain Barrier 1998, 188-197. Cambridge University Press, Cambridge. W.M. Pardridge (Ed.).
70. Staub N.C., Dawson C.A. Pulmonary and bronchial circulation. Comprehensive human physiology 1996, 2071-2078. Springer, Berlin. R. Greger, U. Windhorst (Eds.).
71. Stephensen H., Tisell M., Wikkelso C. There is no pressure gradient in communicating or noncommunicating hydrocephalus. Neurosurgery 2002, 50:763-773.
72. 3H-benzylpenicillin in the cerebrospinal fluid. Neurosci. Lett. 1994, 169:159-162.
73. Van Deurs B. Choroid plexus absorption of horseradish peroxidase from the cerebral ventricles. J. Ultrastruct. Res. 1976, 55:400-416.
74. Van Deurs B. Vesicular transport of horseradish peroxidase from brain to blood in segments of the cerebral microvasculature in adult mice. Brain Res. 1977, 124:1-8.
75. Van Deurs B., Moller M., Amtorp O. Uptake of horseradish peroxidase from CSF into choroid plexus of the rat, with special reference to transepithelial transport. Cell Tiss. Res. 1978, 187:215-234.
76. Van Os C.H., Kamsteeg E.-J., Marr N., Deen P.M.T. Physiological relevance of aquaporins: luxury or necessity?. Pflügers Arch. - Eur. J. Physiol. 2000, 440:513-520.
77. 3H-inulin by CSF pulsations and body activity into various compartments of the CSF. Iugoslav. Physiol. Pharmacol. Acta 1988, 24:489-491.
78. 3H-benzylpenicillin out of the cerebrospinal fluid system. Life Sci. 2000, 67:2375-2385.
79. 3H-inulin between the cerebrospinal fluid compartments. Brain Res. 2009, 1248:127-135.
80. Wagner H.J., Pilgrim Ch., Brandl J. Penetration and removal of horseradish peroxidase injected into the cerebrospinal fluid: role of cerebral perivascular spaces, endothelium and microglia. Acta Neuropath. (Berl.) 1974, 27:299-315.
81. Watson P.D. Effects of blood-free and protein-free perfusion on CFC in the isolated cat hindlimb. Am. J. Physiol. 1983, 245:H911-H919.
82. Wiig H., Reed R.K. Rat brain interstial fluid pressure measured with micropipettes. Am. J. Physiol. 1983, 244:H239-H246.
83. Wolf M.B., Watson P.D. Measurement of osmotic reflection coefficient for small molecules in cat hindlimbs. Am. J. Physiol. 1989, 213:308-314.
84. Yudilevich D.L., Alvarez O.A. Water, sodium and thiourea transcapillary diffusion in the dog heart. Am. J. Physiol. 1967, 213:308-314.
85. Yudilevich D.L., De Rose N. Blood-brain transport glucose and other molecules measured by rapid indicator dilution. Am. J. Physiol. 1971, 220:841-846.
86. Zmajević M., Klarica M., Varda R., Kudelić N., Bulat M. Elimination of phenolsulfonphthalein from the cerebrospinal fluid via capillaries in central nervous system in cats by active transport. Neurosci. Lett. 2002, 321:123-125.
87. Zornow M.H., Todd M.M., Moore S.S. The acute cerebral effects of changes in plasma osmolality and oncotic pressure. Anesthesiology 1987, 67:936-941.
88. Zülch K.J. Neuropathological observation on the cerebrospinal fluid pathway. Ciba Foundation Symposium on the Cerebrospinal Fluid 1958, 230-242. Little Brown and Co., Boston. G.E.W. Wolstenholme, C.M. O'Connor (Eds.).