Homeostatic role of the active transport in elimination of [3H]benzylpenicillin out of the cerebrospinal fluid system

Life Sciences

Volumn 67, Issue 19, 2000, Pages 2375-2385

  Casal, J Antonio ^a   Corzo, M Dolores ^b   Pérez, Luis F ^a   Alvarez, J Antonio ^b   Aldegunde, Manuel ^c   Tutor, J Carlos ^a  

^a Pediatric Nutrition Research Group Health Research Institute of Santiago de Compostela   (Spain)

^b Centro de Investigacion Biomedica EuroEspes   (Spain)

^c UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Acidic metabolites; Active transport; Benzylpenicillin; Cerebrospinal fluid

Indexed keywords

PENICILLIN G; PROBENECID; TRITIUM;

ACTIVE TRANSPORT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CAPILLARY WALL; CISTERNA MAGNA; CONTROLLED STUDY; DOG; DRUG ABSORPTION; DRUG CEREBROSPINAL FLUID LEVEL; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DURA MATER; HOMEOSTASIS; NONHUMAN;

ANIMAL; BIOLOGICAL TRANSPORT, ACTIVE; CEREBROSPINAL FLUID; DOGS; MODELS, ANIMAL; PENICILLIN G; PENICILLINS; PROBENECID; SUPPORT, NON-U.S. GOV'T;

EID: 0034730373     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(00)00823-7     Document Type: Article

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