MR angiogenesis imaging with Robo4- vs. αVβ 3-targeted nanoparticles in a B16/F10 mouse melanoma model

FASEB Journal

Volumn 24, Issue 11, 2010, Pages 4262-4270

  Boles, Kent S ^a   Schmieder, Anne H ^a   Koch, Alexander W ^b   Carano, Richard A D ^b   Wu, Yan ^b   Caruthers, Shelton D ^a   Tong, Raymond K ^b   Stawicki, Scott ^b   Hu, Grace ^a   Scott, Michael J ^a   Zhang, Huiying ^a   Reynolds, Benton A ^a   Wickline, Samuel A ^a   Lanza, Gregory M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GENENTECH INC   (United States)

Author keywords

Integrin; Magnetic resonance imaging; Neovasculature; Roundabout; Tumor

Indexed keywords

ALPHA5BETA 3 PEPTIDOMIMETIC AGENT; AVIDIN; BIOLOGICAL MARKER; GROWTH FACTOR; MAGNETIC NANOPARTICLE; PARAMAGNETIC PERFLUOROCARBON NANOPARTICLE; PEPTIDOMIMETIC AGENT; PROTEIN ROBO4; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CARCINOGENESIS; CONTRAST ENHANCEMENT; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MELANOMA; MOLECULAR IMAGING; MOLECULARLY TARGETED THERAPY; MOUSE; MOUSE STRAIN; NON INVASIVE PROCEDURE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL PROCESSING; TUMOR GROWTH; TUMOR VOLUME;

ANIMALS; BIOLOGICAL MARKERS; DISEASE MODELS, ANIMAL; INTEGRIN ALPHAVBETA3; MELANOMA; MICE; MICE, INBRED C57BL; MICROSCOPY, FLUORESCENCE; MOLECULAR IMAGING; NANOPARTICLES; NEOVASCULARIZATION, PATHOLOGIC; NERVE TISSUE PROTEINS; RECEPTORS, IMMUNOLOGIC; STAINING AND LABELING;

ANIMALIA; MUS;

EID: 78649855174     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.10-157933     Document Type: Article

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