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Volumn 3, Issue 6, 2006, Pages 996-1003

Chronic administration of an oral Rho Kinase inhibitor prevents the development of vasculogenic erectile dysfunction in a rat model

Author keywords

Atherosclerosis; Rats; Rho GTPbinding protein; Vasculogenic impotence

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; FASUDIL; N(G) NITROARGININE METHYL ESTER; RHO KINASE; RHO KINASE INHIBITOR; VON WILLEBRAND FACTOR;

EID: 33750447627     PISSN: 17436095     EISSN: 17436109     Source Type: Journal    
DOI: 10.1111/j.1743-6109.2006.00327.x     Document Type: Article
Times cited : (45)

References (23)
  • 1
    • 0020367772 scopus 로고
    • Arterial disease as a cause of impotence
    • Michal V. Arterial disease as a cause of impotence. Clin Endocrinol Metab 1982; 11: 725-48.
    • (1982) Clin Endocrinol Metab , vol.11 , pp. 725-748
    • Michal, V.1
  • 2
    • 16344374885 scopus 로고    scopus 로고
    • Arteriogenic erectile dysfunction alters protein expression within the cavernosal tissue in an animal model
    • De Young L, Bella A, Howard J, Brock G. Arteriogenic erectile dysfunction alters protein expression within the cavernosal tissue in an animal model. J Sex Med 2005; 2: 199-206.
    • (2005) J Sex Med , vol.2 , pp. 199-206
    • De Young, L.1    Bella, A.2    Howard, J.3    Brock, G.4
  • 3
    • 0029912525 scopus 로고    scopus 로고
    • Study of etiologic relationship of arterial atherosclerosis to corporal veno-occlusive dysfunction in the rabbit
    • Azadzoi KM, Siroky MB, Goldstein I. Study of etiologic relationship of arterial atherosclerosis to corporal veno-occlusive dysfunction in the rabbit. J Urol 1996; 155: 1795-800.
    • (1996) J Urol , vol.155 , pp. 1795-1800
    • Azadzoi, K.M.1    Siroky, M.B.2    Goldstein, I.3
  • 4
    • 0032860424 scopus 로고    scopus 로고
    • Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells
    • Kaibuchi K, Kuroda S, Amano M. Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells. Annu Rev Biochem 1999; 68: 459-86.
    • (1999) Annu Rev Biochem , vol.68 , pp. 459-486
    • Kaibuchi, K.1    Kuroda, S.2    Amano, M.3
  • 5
    • 0033578621 scopus 로고    scopus 로고
    • A rho exchange factor mediates thrombin and Galpha (12)-induced cytoskeletal responses
    • Majumdar M, Seasholtz TM, Buckmaster C, Toksoz D, Brown JH. A rho exchange factor mediates thrombin and Galpha (12)-induced cytoskeletal responses. J Biol Chem 1999; 274: 26815-21.
    • (1999) J Biol Chem , vol.274 , pp. 26815-26821
    • Majumdar, M.1    Seasholtz, T.M.2    Buckmaster, C.3    Toksoz, D.4    Brown, J.H.5
  • 7
    • 0037214686 scopus 로고    scopus 로고
    • Chronic inhibition of Rho kinase blunts the process of left ventricular hypertrophy leading to cardiac contractile dysfunction in hypertension-induced heart failure
    • Satoh S, Ueda Y, Koyanagi M, Kadokami T, Sugano M, Yoshikawa Y, Makino N. Chronic inhibition of Rho kinase blunts the process of left ventricular hypertrophy leading to cardiac contractile dysfunction in hypertension-induced heart failure. J Mol Cell Cardiol 2003; 35: 59-70.
    • (2003) J Mol Cell Cardiol , vol.35 , pp. 59-70
    • Satoh, S.1    Ueda, Y.2    Koyanagi, M.3    Kadokami, T.4    Sugano, M.5    Yoshikawa, Y.6    Makino, N.7
  • 8
    • 0035823041 scopus 로고    scopus 로고
    • Involvement of Rho-kinase in vascular remodeling caused by long-term inhibition of nitric oxide synthesis in rats
    • Ikegaki I, Hattori T, Yamaguchi T, Sasaki Y, Satoh SI, Asano T, Shimokawa H. Involvement of Rho-kinase in vascular remodeling caused by long-term inhibition of nitric oxide synthesis in rats. Eur J Pharmacol 2001; 427: 69-75.
    • (2001) Eur J Pharmacol , vol.427 , pp. 69-75
    • Ikegaki, I.1    Hattori, T.2    Yamaguchi, T.3    Sasaki, Y.4    Satoh, S.I.5    Asano, T.6    Shimokawa, H.7
  • 9
    • 0034955766 scopus 로고    scopus 로고
    • Y-27632, an inhibitor of Rho-kinase, antagonizes noradrenergic contractions in the rabbit and human penile corpus cavernosum
    • Rees RW, Ralph DJ, Royle M, Moncada S, Cellek S. Y-27632, an inhibitor of Rho-kinase, antagonizes noradrenergic contractions in the rabbit and human penile corpus cavernosum. Br J Pharmacol 2001; 133: 455-8.
    • (2001) Br J Pharmacol , vol.133 , pp. 455-458
    • Rees, R.W.1    Ralph, D.J.2    Royle, M.3    Moncada, S.4    Cellek, S.5
  • 12
    • 30744439574 scopus 로고    scopus 로고
    • Initial validation of a novel rat model of vasculogenic erectile dysfunction with generalized atherosclerosis
    • Park K, Son H, Kim SW, Paick JS. Initial validation of a novel rat model of vasculogenic erectile dysfunction with generalized atherosclerosis. Int J Impot Res 2005; 17: 424-30.
    • (2005) Int J Impot Res , vol.17 , pp. 424-430
    • Park, K.1    Son, H.2    Kim, S.W.3    Paick, J.S.4
  • 14
    • 14344255882 scopus 로고    scopus 로고
    • Rho-kinase inhibition improves erectile function in aging male Brown-Norway rats
    • Rajasekaran M, White S, Baquir A, Wilkes N. Rho-kinase inhibition improves erectile function in aging male Brown-Norway rats. J Androl 2005; 26: 182-8.
    • (2005) J Androl , vol.26 , pp. 182-188
    • Rajasekaran, M.1    White, S.2    Baquir, A.3    Wilkes, N.4
  • 16
    • 1942501869 scopus 로고    scopus 로고
    • Effect of chronic ischemia on constitutive and inducible nitric oxide synthase expression in erectile tissue
    • Azadzoi KM, Master TA, Siroky MB. Effect of chronic ischemia on constitutive and inducible nitric oxide synthase expression in erectile tissue. J Androl 2004; 25: 382-8.
    • (2004) J Androl , vol.25 , pp. 382-388
    • Azadzoi, K.M.1    Master, T.A.2    Siroky, M.B.3
  • 17
    • 0032508533 scopus 로고    scopus 로고
    • Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase
    • Laufs U, Liao JK. Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase. J Biol Chem 1998; 273: 24266-71.
    • (1998) J Biol Chem , vol.273 , pp. 24266-24271
    • Laufs, U.1    Liao, J.K.2
  • 20
    • 0742271502 scopus 로고    scopus 로고
    • Phosphorylated endothelial nitric oxide synthase mediates vascular endothelial growth factor-induced penile erection
    • Musicki B, Palese MA, Crone JK, Burnett AL. Phosphorylated endothelial nitric oxide synthase mediates vascular endothelial growth factor-induced penile erection. Biol Reprod 2004; 70: 282-9.
    • (2004) Biol Reprod , vol.70 , pp. 282-289
    • Musicki, B.1    Palese, M.A.2    Crone, J.K.3    Burnett, A.L.4
  • 21
    • 23844523172 scopus 로고    scopus 로고
    • Inactivation of phosphorylated endothelial nitric oxide synthase (Ser-1177) by O-GlcNAc in diabetes-associated erectile dysfunction
    • Musicki B, Kramer MF, Becker RE, Burnett AL. Inactivation of phosphorylated endothelial nitric oxide synthase (Ser-1177) by O-GlcNAc in diabetes-associated erectile dysfunction. Proc Natl Acad Sci USA 2005; 102: 11870-5.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 11870-11875
    • Musicki, B.1    Kramer, M.F.2    Becker, R.E.3    Burnett, A.L.4
  • 22
    • 0036892061 scopus 로고    scopus 로고
    • Rho GTPase/Rho kinase negatively regulates endothelial nitric oxide synthase phosphorylation through the inhibition of protein kinase B/Akt in human endothelial cells
    • Ming XF, Viswambharan H, Barandier C, Ruffieux J, Kaibuchi K, Rusconi S, Yang Z. Rho GTPase/Rho kinase negatively regulates endothelial nitric oxide synthase phosphorylation through the inhibition of protein kinase B/Akt in human endothelial cells. Mol Cell Biol 2002; 22: 8467-77.
    • (2002) Mol Cell Biol , vol.22 , pp. 8467-8477
    • Ming, X.F.1    Viswambharan, H.2    Barandier, C.3    Ruffieux, J.4    Kaibuchi, K.5    Rusconi, S.6    Yang, Z.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.