A putative Alzheimer's disease risk allele in PCK1 influences brain atrophy in multiple sclerosis

PLoS ONE

Volumn 5, Issue 11, 2010, Pages

  Xia, Zongqi ^a,b   Chibnik, Lori B ^a,b   Glanz, Bonnie I ^a   Liguori, Maria ^c,e   Shulman, Joshua M ^a,b   Tran, Dong ^a,b   Khoury, Samia J ^a   Chitnis, Tanuja ^a   Holyoak, Todd ^d   Weiner, Howard L ^a   Guttmann, Charles R G ^c   de Jager, Philip L ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^e INSTITUTE OF NEUROLOGICAL SCIENCES   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CLUSTERIN; COMPLEMENT COMPONENT C3B RECEPTOR; HLA B44 ANTIGEN; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL BINDING CLATHRIN ASSEMBLY PROTEIN; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PHOSPHOENOLPYRUVATE CARBOXYKINASE 1; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; ZINC FINGER PROTEIN 224; HLA B ANTIGEN; HLA B*4403 ANTIGEN; HLA-B*4403 ANTIGEN; PCK1 PROTEIN, HUMAN; SIGNAL PEPTIDE;

ADULT; ALZHEIMER DISEASE; ARTICLE; BRAIN ATROPHY; COGNITION; CONTROLLED STUDY; FEMALE; FOLLOW UP; GENE LOCUS; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; SINGLE NUCLEOTIDE POLYMORPHISM; ALLELE; ATROPHY; BIOLOGICAL MODEL; BRAIN; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROSPECTIVE STUDY; RISK FACTOR;

ADULT; ALLELES; ALZHEIMER DISEASE; ATROPHY; BRAIN; COGNITION; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HLA-B ANTIGENS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MODELS, GENETIC; MODELS, NEUROLOGICAL; MULTIPLE SCLEROSIS; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); POLYMORPHISM, SINGLE NUCLEOTIDE; PROSPECTIVE STUDIES; RISK FACTORS;

EID: 78649836872     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0014169     Document Type: Article

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